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RESEARCH HIGHLIGHT 31 October 2025 Modelling shows how the infant Universe might have stayed warm and dense during its primoridal expansion.
Rapalogix Health launches Re-Q, a skincare line featuring an mTORC1-selective inhibitor that connects geroscience with dermatology. For more than a decade, rapamycin has been the poster molecule for longevity research – the compound that extended lifespan in mice yet stumbled at the clinic under the weight of its immunosuppressive baggage. The challenge has been to tame mTOR, that central metabolic conductor, without muting essential immune or insulin-signalling functions. Now, a new entrant is attempting to do just that, albeit through a different route – the skin. Rapalogix Health, a spinout from Cambrian Bio, has unveiled Re-Q Health, a longevity-inspired skincare…
Nutriearth has inaugurated its first commercial manufacturing site for producing natural and sustainable vitamin D3 from an edible insect in Carvin, France. The company’s patented, biomimetic technology aims to set new standards for effectiveness, sustainability, and safety in the field. Backed by more than 60 global patents, Nutriearth’s breakthrough lies in its unique processing method of the nutritious Tenebrio molitor (mealworm), which has been consumed in various cultures for thousands of years.When comparing mealworm-sourced vitamin D3 to the conventional lanolin-derived option, an independent Life Cycle Assessment found it is 76.8% lower in greenhouse gas emissions with an eightfold lower overall…
Credit: Institute for Bioengineering of Catalonia A pioneering technology has been developed that enables human kidney organoids to be produced in a scalable manner by allowing the organoids to be combined with ex vivo pig kidneys and then transplanted back into the same animal to evaluate their viability. The work is published in Nature Biomedical Engineering, in the paper, “Systematic production of human kidney organoids for transplantation in porcine kidneys during ex vivo machine perfusion.” The findings are a significant milestone in regenerative and personalized medicine, paving the way for the use of kidney organoids derived from human stem cells…
A new study suggests walking for 10 minutes or more at a time may be better than shorter spurts.Those who regularly walked for 10 to 15 minutes had a significantly lower risk of heart disease.Be intentional with walking for at least 10 minutes at a time most days, and aim for 15 when you can. It’s no secret that regular physical activity is linked with a lower risk of heart disease. Whether you enjoy resistance training or cardio exercise, they all have benefits for the heart. But when it comes to just how much exercise is necessary to reap heart…
Kamran Abbasi, editor in chiefThe BMJkabbasi{at}bmj.comMention China to a medical journal editor, and their mind will leap to studies on irrelevant research questions drawn from the UK Biobank. It might also jump to numerous analyses of Global Burden of Disease study data. It will inevitably dwell on risks of research misconduct and ethical breaches. The overriding sentiment, however, might be: how do we get through an avalanche of substandard submissions seeking an international journal with an impact factor?On a recent trip to China I championed the advice of Doug Altman, The BMJ’s former chief statistician who not only led the…
This week’s dinner plan features recipes that are ready in 4 steps (or less!)—plus they follow the principles of the Mediterranean diet.Adhering to the Mediterranean diet—prioritizing grains, veggies, beans, lean proteins and healthy fats—can boost heart health, brain health and more.From our salmon Caesar salad to a comforting chickpea soup, you’ll enjoy balanced meals that support wellness all week. What I like about the Mediterranean diet is that it’s not restrictive and it’s easy to follow. And it can help with just about any health condition—it can help lower your cholesterol, reduce inflammation and even reduce your risk of developing…
Cheng Lyu, PhD., Postdoctoral Fellow at Stanford University, California, USA, wins the Eppendorf & Science Prize for Neurobiology for his work on rewiring the olfactory neural circuit in fruit flies. “Cheng Lyu’s winning essay describes the molecular mechanisms how olfactory receptor neurons choose one synaptic partner out of all potential candidates” said Peter Stern, Senior Editor at SCIENCE and Prize Jury Chair. “These results provide a profound understanding of the principles of neural circuit assembly.” “We found that the fly olfactory neural circuit builds its three-dimensional structure by breaking the developmental task into a series of one-dimensional steps”, says Lyu.…
Nature, Published online: 31 October 2025; doi:10.1038/d41586-025-03566-8In a world first, a bespoke gene-editing therapy benefitted one child. Now reseachers plan to launch a clinical trial of the approach.
Credit: Dr_Microbe/Getty Images Researchers at St. Jude Children’s Research Hospital have discovered a way to turn a multi-drug bacterium’s defenses against itself, a finding that opens new pathways to help combat increases in antibiotic-resistant infections. The research, published in Nature Biotechnology, details the use of a structurally modified form of the drug florfenicol hijacks the resistance mechanism in Mycobacterium abscessus, to amplify the drug’s effect “in perpetuity.” “One of the most prominent groups at risk of M. abscessus infections is critically ill patients, like we have at St. Jude,” said senior author Richard Lee, PhD, a member of the department…