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Credit: Sinhyu/iStock/Getty Images Plus Scientists at Tel Aviv University in collaboration with scientists at Harvard Medical School have developed a new gene therapy that restores hearing and balance in animals with mutations in a gene not previously targeted for this kind of treatment. The gene therapy, described in EMBO Molecular Medicine, targets the CLIC5 gene which maintains the structure and stability of sensory hair cells in the inner ear and employs an optimized AAV vector for delivery—self-complementary AAV (scAAV). “The inner ear consists of two highly coordinated systems: the auditory system, which detects, processes, and transmits sound signals to the…
Designed to simulate up to 40 years of skin aging under various lifestyle, dietary and environmental conditions, the tool offers a new visualization layer for stakeholders across wellness, nutrition and dietary supplement sectors.“This visualization turns abstract health advice into undeniable reality, motivating action today for a longer, healthier tomorrow,” Anastasia Georgievskaya, CEO and co-founder of Haut.AI shared in a statement, explaining that the tool allows consumers to “see their future selves—healthy or unhealthy—side by side.” The SkinGPT Aging Model builds on Haut.AI’s existing platform for virtual try-ons and personalized skin analysis using the company’s proprietary skin analysis engine and introduces…
An AlphaFold3 model of a protein (blue) interacting with RNA (purple).Credit: Google DeepMindScientists today released a ‘sneak preview’ of a new open-source artificial intelligence (AI) model that predicts 3D structures of proteins, and say it is close to matching the performance of Google DeepMind’s revolutionary protein-folding AI AlphaFold3.The system, called OpenFold3, was developed by the OpenFold Consortium1, a non-profit collaboration of academic and private research groups, headquartered in Davis, California. OpenFold3 uses proteins’ amino acid sequences to map their 3D structures and model how they interact with other molecules, such as drugs or DNA.The tool still doesn’t have the same…
A new study in Sweden has found that food taxes can bring environmental and human health benefits without raising the average grocery bill. Researchers at Chalmers University of Technology say food taxes could potentially prevent 700 premature deaths among people under 70 each year in the nation. “This high figure surprised us, and yet it is a conservative estimate. There is also a lot of suffering associated with unhealthy diets that is not apparent in this figure, such as living with obesity or type 2 diabetes,” says lead researcher Jörgen Larsson at Chalmers University of Technology.The researchers have proposed removing VAT…
Female mosquitoes decide whether mating will take place or not through a lock-and-key mechanism. However, other mosquito species can lockpick this process.Image credit:Jacopo Razzauti/The Rockefeller UniversitySome animals, from puffins and swans to prairie voles, are known to mate for life. For female mosquitoes, mating typically occurs once in their lifetime—lasting under 30 seconds—before the couple go their separate ways. This brief encounter is crucial for both reproductive success and mosquito control efforts, as offspring from parents of different species are sterile.However, the intimate details that drive mosquito mating and the mechanisms that control cross-species mating remain poorly understood. This motivated…
It’s a hearty one-pan meal perfect for weeknights and serving guests. Plant-based protein and fiber from the chickpeas and brown rice will keep you satisfied. You can cut down on preparation time by using pre-chopped onions or frozen chopped spinach. Our Chickpea Casserole is a plant-forward dish that will exceed your expectations. The aromatics are the foundation of this dish—antioxidant-rich garlic and onions are heated in heart-healthy extra-virgin olive oil—your kitchen will smell amazing. The fiber punch from the chickpeas and rice will keep you full, while the brightness of the lemon and dill will tickle your taste buds. Salty feta…
A new study links eating nuts regularly to lower risk of heart disease deaths.Tree nuts like almonds, cashews and walnuts showed the strongest benefits.Replacing red or processed meat with nuts may further support heart health. Nuts have long been linked to heart health, and new research continues to explore how they might help protect against heart disease. Researchers wanted to know how regular nut consumption affects heart health over time. Their new study offers a clearer look than earlier research thanks to a larger, more diverse group of participants and a longer follow-up period. Heart disease remains the leading cause…
Company is first to demonstrate restoration of vision in clinical trial of BCI tech in patients with geographic atrophy. A clinical trial published in The New England Journal of Medicine has demonstrated that Science Corporation’s brain-computer interface (BCI) retinal implant can restore functional central vision to patients with an advanced form of age-related macular degeneration (AMD), one of the leading causes of blindness worldwide. The publication is the first peer-reviewed confirmation that patients with geographic atrophy regained so-called “form vision” – the ability to perceive shapes, letters and words – through a wireless retinal prosthesis. It is estimated that more…
When the United Nations negotiations on plastic pollution in Geneva, Switzerland, collapsed in August, observers declared the outcome an abject failure and the process broken. Earlier this month, reports that the chair of the talks, ambassador Luis Vayas Valdivieso, would step down deepened uncertainty.Trust and science: the essential elements missing from plastics treaty talksMany media outlets saw a failure of multilateralism, but what I saw was fatigue. Just as the ‘failed’ 2009 Copenhagen climate summit paved the way for the 2015 Paris agreement, this plastics-treaty breakdown could be an inflection point — if we learn the right lessons and rethink…
Go High IntensityStatic lifts like curls and deadlifts are important for building raw muscle and strength, but high-intensity sessions with intervals and burnouts can help. Research shows that high-intensity interval training promotes lean mass, maximal strength, and lower-limb muscle power.High-intensity workouts apply to the cardio and strength training sides of your program.For cardio, training sessions that involve all-out sprints, running stairs, and pushing hard in short bursts with short breaks between each burst will push the limits of your cardio while burning calories rapidly. The elevated heart rate and anaerobic type of training that come with high-intensity workouts help create…