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Jane Goodall, a British primatologist known for her work with chimpanzees, died on Wednesday 1 October, aged 91. She was in California on a speaking tour and died of natural causes, according to the Jane Goodall Institute.Goodall is best known for her work with chimpanzees in Gombe National Park in Tanzania. She was the first to discover that chimpanzees made and used tools1. She went on to become an advocate for conservation, human rights and animal welfare, including stopping the use of animals in medical research. She established the Jane Goodall Institute, a non-profit wildlife and conservation organization in Washington…

Derm-Biome’s compound prevented epidermal thickening, reduced cellular senescence and preserved collagen levels under UV stress. Skin-focused biopharma Derm-Biome Pharmaceuticals is advancing an experimental topical compound that may offer a new approach to slowing or preventing skin aging caused by ultraviolet light. The candidate, known as DB-006, was one of three molecules recently tested by the company in a preclinical photoaging study, where it showed unexpectedly strong activity against hallmark features of sun-related skin decline. DB-006 emerged as part of Derm-Biome’s primary mission to develop treatments for inflammatory skin diseases and skin cancers. Initially identified through the Vancouver-based company’s program focused…

What’s better than a comforting bowl of creamy pasta? Not only are these healthy dishes satisfying and delicious, they’ve all been saved hundreds of times by users on MyRecipes to make again and again. From high-protein options like our Lemon Chicken Orzo to 20-minute favorites like our Spaghetti & Spinach with Sun-Dried Tomato Cream Sauce, these dishes are the perfect answer to your weeknight needs. Love any of these recipes? Join MyRecipes to save, search and organize your EatingWell recipes all in one place. It’s free! High-Protein Lemon Chicken Orzo Photographer: Morgan Hunt Glaze, Food Stylist: Julian Hensarling, Prop Stylist:…

Israel has carried out at least 17 attacks on or in the vicinity of healthcare facilities in Gaza City since 16 September), the UN has said.Three healthcare facilities—Al Quds Hospital, Al Rantisi Children’s Hospital, and the Medical Relief Health Centre—have all been directly hit, while further strikes were recorded in the vicinity of two more, Al Shifa Medical Complex and Al Ahli Hospital.The Jordanian field hospital in Tal Al Hawa was also forced to evacuate to Al Mawasi in Khan Younis after Israeli strikes damaged the facility. And the Palestinian Red Crescent Society reported that Israeli ground forces had besieged…

Pathogenic Salmonella bacteria background. 3d illustration. [iLexx/ iStock / Getty Images Plus] Researchers at the University of Liverpool have discovered how pathogenic bacteria construct protein-based compartments known as ethanolamine utilization (Eut) microcompartments, which are essential for breaking down ethanolamine (EA), a nutrient abundant in the gut. The research, published in Science Advances, details how the Eut microcompartments enable bacteria to digest ethanolamine to give them a competitive advantage over commensal microbes, fostering bacterial growth and virulence. “It was known that bacteria build these compartments to safely and efficiently digest ethanolamine, but our research reveals the precise molecular steps involved,” said…

Sabrina Carpenter shared her mom’s 7-ingredient cheesy dip recipe in a new cooking video.She also revealed her “go-go juice” cocktail with tequila or vodka, pineapple juice, ginger ale and lime.The dip is quick, no-bake and perfect with chips or veggies—easy to prep ahead for guests. Sabrina Carpenter is a woman of many talents, from being a Grammy Award-winning singer-songwriter to stints as a Broadway actor and film star. Carpenter admits that her talents are more limited in the kitchen, but she’s still game to whip up some family recipes and go-to beverages in a new video. Let’s just say we…

Universities must do more to prepare engineering students to manufacture cell and gene therapies, according to new analysis, which suggests few degree-level training courses cover the specialist skills required. The problem, says author Andy Tay, PhD, from the National University of Singapore, is that most programs still focus on large molecule drug production. “[Cell, tissue, and gene therapy products] (CTGTP) manufacturing differs from traditional biopharmaceutical production. In traditional manufacturing, the cells are used as hosts to produce the therapeutic antibodies etc., whereas in the CTGTP sector, we use the cells as the medicine. “Hence, the steps used to isolate and…

DNA-synthesis firms routinely use -biosecurity-screening software to ensure that they don’t inadvertently create dangerous sequences. But a paper published in Science on 2 October describes a potential vulnerability in this workflow1.It details how protein-design strategies aided by artificial intelligence (AI) could circumvent the screening software that many DNA-synthesis firms use to ensure that they avoid unintentionally producing sequences encoding harmful proteins or pathogens.The researchers used an approach from the cybersecurity world: ‘red teaming’, in which one team attempts to break through another’s defences (with their knowledge). They found that some screening tools were unprepared to catch AI-generated protein sequences that…

Fructose intolerance is a condition in which the body has difficulty digesting fructose, a natural sugar found in fruits, some vegetables, and added sweeteners such as high-fructose corn syrup . There are two main types of this condition: hereditary fructose intolerance, which is a rare genetic disorder, and fructose malabsorption, which is a more common digestive condition. While hereditary fructose intolerance is a lifelong disorder that requires strict dietary management, fructose malabsorption is a nongenetic condition that is often managed through dietary changes. Neither condition is curable, but both are treatable. Here’s everything you need to know about fructose intolerance…

Linking single cell functional insights with sequencing data provides unprecedented insight into the translational potential of cell therapies.Image credit:istock, ru3apr The growing understanding that most diseases are related to cellular dysfunction and dysregulation has researchers probing single cells to uncover the molecular mechanisms that contribute to disease and inform the development of novel therapeutics.Single-cell sequencing allows scientists to differentially categorize cells based on their gene expression. However, gaining insights into cell function by direct measurement, rather than inference, can be challenging. To enable this, scientists from Bruker Cellular Analysis developed a cutting-edge platform named Beacon Discovery™, a microfluidic chip-based technology that…