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Current regulations may not be sufficient to mitigate the effects of widespread and long lasting PFAS. Katharine Lang looks at the issueRecent news has highlighted concern about the presence in drinking water of perfluoroalkyl and polyfluoroalkyl substances (PFAS), a group of more than 10 000 synthetic chemicals that have been used in consumer products since the 1950s.The non-stick, water repelling, and grease repelling properties of PFAS mean they are widely used. Skin creams and cosmetics, floor and car polish, dishwasher rinse aid, fabric treatments, food packaging, non-stick cookware, and outdoor clothing and shoes are just some of the household items that…
Credit: nopparit / iStock / Getty Images Identifying the mechanisms of action driving a drug’s anti-cancer efficacy is critical for identifying optimal biomarkers, indications, and combinations for clinical success. Yet, systematically identifying these mechanisms remains challenging, as drugs often engage in multiple targets with varying affinities across different cellular contexts. In a new study published in npj Precision Oncology titled, “DeepTarget predicts anti-cancer mechanisms of action of small molecules by integrating drug and genetic screens,” researchers from Sanford Burnham Prebys Medical Discovery Institute and the National Institutes of Health (NIH) have developed DeepTarget, a computational tool that integrates large-scale drug and genetic knockdown viability screens with omics…
Costco’s holiday wine lineup features budget-friendly sommelier-approved picks for every festive occasion.Top choices include Santa Margherita Pinot Grigio, Trefethen Dry Riesling and Marques de Riscal Reserva.Daou’s 3-Liter Cabernet Sauvignon is perfect for large gatherings and family celebrations this season. ’Tis the season for a glass of wine with your favorite comfort foods, and Costco has some incredible bottles for you to choose from. Whether you’re hosting a holiday dinner this season or looking for a tasty host gift, these wines are loved by sommeliers. Safe to say, they’re bound to be impressive. From crisp white wines to bubbly rosé, here…
Both prebiotics and probiotics support a happier, healthier gut. If you’re wondering which is better, prebiotics help promote longer-term gut health. You can get prebiotics from oats, garlic, onions, leeks, asparagus and bran cereal. Gut health has officially gone mainstream. Between January 2018 and October 2019 alone, more than 830 articles on the topic were published in the U.S. and Canada. Yet, while many headlines hype the latest gut-health trends, few actually break down the science behind them. That’s where we come in. With gut health in the spotlight, it seems like every supplement brand has a prebiotic or probiotic product it…
If you’ve ever blamed your hormones for brain fog or slower thinking, you’re far from alone. Many women report feeling less focused or sharp during certain phases of their menstrual cycle. But new research published in Sports Medicine challenges that long-held assumption.
Photodynamic therapy was initially used to treat skin cancer. While that’s still its primary use, it’s also used to treat other types of cancers and conditions.FDA-Approved UsesPDT has been approved to treat the following conditions.Actinic Keratoses (Precancerous Skin Lesions) PDT is approved for treating actinic keratoses, particularly on the face, scalp, and arms, says Aaron Farberg, MD, a double board-certified dermatologist who specializes in skin cancer, inflammatory diseases, and cosmetic dermatology at Bare Dermatology in Dallas.Superficial Basal Cell Carcinoma (BCC) and Bowen’s Disease PTD is approved to treat superficial basal cell carcinoma and Bowen’s disease, also known as squamous cell carcinoma…
In the ever-expanding world of “better-for-you” beverages, Poppi has emerged as a vibrant, social-media-famous contender, painting itself as a modern, gut-friendly alternative to traditional soda. With its candy-colored cans, promises of prebiotic benefits from apple cider vinegar, and a range of nostalgic flavors, it’s captured the attention of health-conscious consumers and soda lovers alike. But as with any new wellness trend, the questions come fast and thick. Consumers today are label-savvy; they want to know exactly what they’re putting into their bodies. One of the most persistent questions floating around the internet, from Reddit threads to parenting blogs, is: Does…
Credit: Eco Clement/UPI/AlamyCosmologist George Smoot contributed to our understanding of the Universe on the largest scales and at the earliest observable times by measuring temperature variations in the cosmic microwave background. His key experiment in 1992 reported detecting these ‘ripples’ in the microwave sky. Smoot’s discovery, for which he won a share of the Nobel Prize in Physics in 2006, revealed the long-anticipated traces of the formation of structures including stars and galaxies (G. F. Smoot et al. Astrophys. J. 396, L1–L5; 1992). This work led to many similar experiments, which used ever-more-precise measurements to cement our modern description of…
It’s very normal to have trouble sleeping when you’re not in your own cozy, perfectly personalized bed. If you’re traveling for the holidays, being intentional with alcohol, staying active, minding your blood sugar, taking a sleep supplement, and sticking to your usual routine as much as possible will help you get the sleep you need to wake up refreshed and ready to ring in the last few days of the year.
The High Court has quashed a GP’s suspension from the UK medical register after finding that the tribunal that sanctioned her had applied the wrong test for dishonesty and reversed the burden of proof.1Sarah Alam was suspended for three months in April this year after a medical practitioners tribunal ruled that she had dishonestly made retrospective notes in practice records stating that 14 patients with chronic conditions had been invited orally for an annual review.Alam, who was the senior partner at the Ulam Medical Centre in Blackburn, Lancashire, made the notes over the Easter weekend in 2018 to comply with…