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New Roots Films follows Longevity Hackers with sequel aiming to bring longevity biotech, clinics and prevention into sharper mainstream focus. A new documentary film, Longevity Revolution, is in development from New Roots Films, the team behind Longevity Hackers – and it is positioning itself as the “next chapter” in how longevity science is communicated to a broader audience. The project is billed as a deeper exploration of the longevity industry, moving beyond the early, often biohacker-led narrative toward a more mature portrait of research, technology and translation. Directed by Emmy-nominated filmmaker Michal Siewierski and co-produced by entrepreneur and author Ruben…

Credit: satura86/Getty Images A model using a complex form of artificial intelligence (AI) can accurately predict how effective cochlear implants are at improving spoken language in young deaf children. The deep transfer learning (DTL) model, which was developed by researchers at the Chinese University of Hong Kong and Ann & Robert H. Lurie Children’s Hospital of Chicago and published in JAMA Otolaryngology–Head & Neck Surgery, predicted language outcomes in young deaf children with an accuracy of 92.4%. More than 180,000 deaf adults and children in the U.S. have cochlear implants, but this is only a small proportion of those who…

Credit: Kateryna Kon/Science Photo Library/Getty Images As tissues age, they quietly accumulate many mutations that can drive cancer. In the hematopoietic system, such mutations often appear in otherwise healthy individuals as clonal hematopoiesis (CH), a process in which certain blood stem cell (HSC) clones gain a growth advantage over non-mutated clones, allowing them to expand steadily over time. A condition known as CHIP (clonal hematopoiesis of indeterminate potential) is associated with an increased risk of blood cancers as well as other chronic illnesses, including heart disease. However, not all those with CHIP develop disease, and some mutant stem cell clones…

Spiral down the sequence of clues to crack the genomic code.

Credit: HeitiPaves/Getty Images Researchers at The University of Texas MD Anderson Cancer Center have found a link between genes that regulate the biological clock and a biomarker of innate immunity that is activated during infections. In a study published in Science Advances, they showed that alterations in the circadian rhythm of C. elegans—which carry similar circadian clock genes to humans—can determine how susceptible their offspring is to bacterial infections.  “These findings reveal a circadian mechanism that can create significant differences in infection outcomes even when genetics and environment are similar,” said Alejandro Aballay, PhD, professor of genetics and dean of…

Air sacs in the lungs called alveoli are crucial for gas exchange and provide an important barrier against inhaled viruses and bacteria that cause respiratory diseases like flu and tuberculosis (TB). However, there remains a gap in developing immunocompetent and experimentally accessible alveolar systems to study human respiratory diseases.  In a new study published in Science Advances titled, “Autologous human iPSC–derived alveolus-on-chip reveals early pathological events of Mycobacterium tuberculosis infection,” researchers from the Francis Crick Institute and AlveoliX have developed what they describe as the first human lung-on-a-chip model using stem cells taken from a single human donor. The chip can simulate breathing motions and lung disease…

Longevity.Technology expands editorial output with launch of new podcast, Longevity.Technology UNLOCKED, premiering on 5 January 2026.  The twice-weekly series will feature in-depth discussions with leading scientists, innovators, and investors shaping the future of healthspan and longevity, and a weekly news summary analysing the latest research, funding developments, and product news from the longevity ecosystem. The podcast will be hosted by Phil Newman, founder and CEO of Longevity.Technology, and Dr Nina Patrick, a pharmaceutical science PhD, longevity researcher, and thought leader behind the Nina’s Notes newsletter, podcast and YouTube channel. Dr Nina Patrick, co-host of Longevity.Technology UNLOCKED “There’s a lot of information circulating in the…

In 2003, Jean-Michel Claverie made a discovery in bacterial genomics that would change his career trajectory and begin a new era in microbiology. “One day, we found a very strange beast that nobody could characterize,” Claverie, now a semi-retired bioinformatician at the Aix-Marseille University, said, “It was not responding to the regular tests for bacteria.” Growing in an amoebal host, this ‘beast’ had been isolated from a water-cooling tower in England following a pneumonia outbreak a decade earlier. It looked and acted like a parasitic bacterium, yet it could not be extracted using any established protocols, nor amplified using universal…

This postdoc investigates the role of neurochemical signaling in the aging brain, aiming to uncover new ways to treat neurodegenerative conditions.Image credit:YA, ©iStock.com, Rasi BhadramaniQ | Write a brief introduction to yourself including the lab you work in and your research background. My name is Yousef Aljohani. I am a postdoctoral researcher specializing in aging neuropharmacology, with a PhD from Georgetown University on NMDA-mediated norepinephrine regulation in the aging brain. Recently, in the Andersen Lab at the Buck Institute, I have focused on neurodegenerative disease mechanisms and cell-based therapeutic strategies, integrating pharmacology with synthetic receptor engineering.Q | How did you…

New waist-focused criteria suggest more than 75% of adult Americans may meet obesity guidelines than previously thought. Obesity has always been defined by a simple equation: height divided by weight, better known as body mass index (BMI). It is fast, cheap and familiar. However, according to a new study published in JAMA Network Open, it may also be missing the bigger picture. Researchers found that when obesity is defined using not just BMI, but also waist-based measurements, more than 75% of US adults could meet the criteria – nearly double the current estimate of around 40%. The finding reframes obesity…