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Cooling the brains of mice with traumatic brain injury by activating hibernation neurons helped them recover faster.Image credit:© iStock.com, hannuramaCooling down a damaged brain can protect neurons by suppressing inflammation.1 But lowering the body temperature externally comes with a host of complications and can lead to impaired clotting and cardiac arrhythmias.Now, researchers led by Takeshi Sakurai at the University of Tsukuba have found a way to leverage hypothermia without causing adverse effects. In a study published in The Journal of Neuroscience, Sakurai and his team showed that cooling the brain from within by activating a specific population of hibernation neurons…

John B Doyle, assistant professor of medicine1 2, Jocelyn Silvester, associate professor of pediatrics3, Jonas F Ludvigsson, professor of clinical epidemiology4 5, Benjamin Lebwohl, professor of medicine and epidemiology1 21Celiac Disease Center, Columbia University Medical Center, New York, NY, USA2Department of Medicine, Division of Digestive and Liver Diseases, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA3Department of Medicine, Division of Gastroenterology, Hepatology and Nutrition, Boston Children’s Hospital, Boston, MA, USA4Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden5Department of Pediatrics, Örebro University Hospital, Örebro, SwedenCorrespondence to: B Lebwohl bl114{at}cumc.columbia.eduABSTRACTCeliac disease is an immune mediated disorder…

A new study of young rats fed a ketogenic diet — high in fat and very low in carbohydrates — supports that it may protect from long-lasting prenatal stress from time spent in the womb. In the trial, researchers stressed pregnant rats in the final week before birth. They weaned the offspring at 21 days after birth and assigned them either a control diet or a ketogenic diet.They tested the young rats at 42 days for various stress-induced deficits, including poor sociability or lack of interest in their surroundings (anhedonia).The animals that had received the ketogenic diet showed some notable…

Pan, Y. et al. The enduring world forest carbon sink. Nature 631, 563–569 (2024).Article  ADS  CAS  PubMed  Google Scholar  Cox, P. M. et al. Sensitivity of tropical carbon to climate change constrained by carbon dioxide variability. Nature 494, 341–344 (2013).Article  ADS  CAS  PubMed  Google Scholar  Koch, A., Hubau, W. & Lewis, S. L. Earth System Models are not capturing present‐day tropical forest carbon dynamics. Earths Future 9, e2020EF001874 (2021).Article  ADS  CAS  Google Scholar  Bauman, D. et al. Tropical tree mortality has increased with rising atmospheric water stress. Nature 608, 528–533 (2022).Article  CAS  PubMed  Google Scholar  Brienen, R. J. W. et…

Making soup from scratch is a great way to use up your late summer bounty and newly in-season veggies, like butternut squash and sweet potato. Skip the store-bought versions and try some of our favorite takes on classic, comforting recipes that taste even better homemade. From our highly-rated Sweet Potato & Black Bean Chili to our classic-but-elevated Sichuan Ramen Cup of Noodles with Cabbage & Tofu, these hearty bowls are the adaptable, better-for-you version of anything you’ll find on the shelf. Love these recipes? Join MyRecipes to save them all with one click. It’s so easy—and free!  Tomato Soup Sonia…

These healthy and delicious vegetable sides are popular for a reason. Our melt-in-your-mouth recipes are the perfect dish that will impress everyone at your table, whether you’re hosting a crowd or dining solo. From our sweet and savory Melting Beets with Feta & Pistachios to classic Garlic-Parmesan Melting Potatoes, you can save all of these to a collection in MyRecipes with a single click. Love these recipes? Join MyRecipes to save them all with one click. It’s so easy—and free!  Melting Beets with Goat Cheese Photography / Jacob Fox, Styling / Sammy Mila Roasting the beets with broth makes them…

Credit: Skodonnell/Getty Images Artificial intelligence’s (AI) predictive capabilities will help the vaccine industry optimize manufacturing, reduce production costs, and increase patient access to lifesaving jabs. That, at least, is the forecast of Addepally Uma, PhD, from the University College of Engineering, Science & Technology, Hyderabad, India, who is co-author of a new study looking at vaccine production optimization challenges. “Vaccines are made using complex biological systems that require multiple unit operations to get pure antigen, which increases costs., she says. “For example, when making the recombinant protein component in vaccines, upstream media can account for 40–50% of the cost. Likewise, downstream…

Luke TaylorRio de JaneiroTwo major academic publishers have begun automatically rejecting most papers submitted using public health datasets, sparking a debate over how to combat “paper mills” that are likely using artificial intelligence to churn out research before selling it on.Both PLOS and Frontiers announced last month that any proposals that use certain public datasets will be rejected out of hand after an investigation showed that hundreds of similar papers reporting spurious findings had been published in leading journals.Any submission to PLOS and Frontiers’ open access journals that use datasets such as the National Health and Nutrition Examination Survey (NHANES),…

Some people notice an increase in feelings of hunger after they start to take vitamin or mineral supplements. Although supplementation may affect hunger in certain situations, increased appetite is typically due to another cause.Supplements and AppetiteThere is very little research suggesting that vitamin and mineral supplements increase hunger. One survey of 330 people in Saudi Arabia who used dietary supplements found that a majority of them — 59.8 percent — reported increased appetite as a positive effect of supplementation, however.It’s important to note that this research relied on self-reported results; it didn’t attempt to objectively confirm that using supplements was…

Specific sets of neurons within particular brain regions get activated in response to binge drinking, offering potential targets to develop treatments for compulsive alcohol consumption.Image credit:© iStock.com, South_agencyWhether it is a Friday-night drink with friends, a quiet glass of wine to unwind after a long day, or as a wedding toast, alcohol has woven itself into celebration, comfort, and routine. This seemingly innocent habit can give way to binge drinking, which can lead to addiction. Gilles Martin studies the neuronal circuits underlying binge alcohol drinking using mice models and techniques such as electrophysiology, optogenetics, and transcriptomics.Gilles Martin“The drugs that we…