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Researchers used base editing to correct a point mutation in the lamin A (LMNA) gene in mice.Image credit:©iStock, Albina LavrentyevaPoint mutations in the lamin A (LMNA) gene cause several human diseases, ranging from congenital muscular dystrophy to premature aging, collectively known as laminopathies, which affect skeletal muscles and the heart. While existing therapies can mitigate the symptoms of these conditions, there is no cure.Base-editing methods have recently emerged as tools for correcting point mutations without creating double-stranded breaks in DNA unlike other gene editing methods, leading many to consider base editing a safer therapeutic strategy. However, base editing of LMNA-associated…

Jack W. Baker had to unexpectedly combat an accusation of plagiarism. It taught him something about keeping science transparent.Credit: Yuri Hobart/StanfordMore than ten years ago, my student and I were accused of misconduct. The issue was our just-published paper in a journal. Our accuser pointed to his own recent publication, which had a nearly identical scope to ours. He claimed we were aware of his previous work and had intentionally not cited it because of a lack of “scientific ethics”. He also alleged that we had abused our privilege, characterizing us as a well-known research group that deliberately ignored work…

Last week’s headlines included the International Probiotics Association (IPA) opening a new Shanghai office, concerns over imported melatonin products in Australia, the return of NMN supplements to Amazon US, and the winners of the 2025 Healthspan Innovators. The International Probiotics Association (IPA) has officially opened its China office located in Shanghai. This is the first office that IPA has set up in Asia-Pacific.George Paraskevakos, IPA’s executive director, said that the new office responds to growing membership of Chinese companies, as well as to set up a touch point in Asia-Pacific (APAC)—which is the region with the biggest probiotic market.“APAC is…

Chronic inflammation can wreak havoc on our health, including stiff joints, digestive trouble and an increased risk of heart disease.. Since poor diet quality can be a culprit of inflammation, certain foods may help—starting with breakfast. And preparation doesn’t have to take long. These simple anti-inflammatory breakfasts come together in 15 minutes or less, and each recipe contains some of the best anti-inflammatory foods out there, like leafy greens, avocados and more. Recipes like our Green Smoothie and our Chickpea & Kale Toast are healthy, satisfying ways to start the day. Love any of these recipes? Join MyRecipes to save,…

As the effects of the ceasefire begin to settle over Gaza, the World Food Programme (WFP) reveals it is moving swiftly to turn the pause in fighting into a lifeline. For the first time in months, humanitarian corridors are opening — and with them, the chance to reach millions of Palestinians cut off from basic sustenance after two years of devastating conflict.According to the WFP, the territory’s food systems lie in ruins. Markets are bare, supply chains have been shattered, and hundreds of thousands of families remain displaced.Now, WFP is launching a large humanitarian scale-up in an attempt to restore…

If you’re eating more high-protein meals these days, you’ll want to try these cozy, satisfying soups, bursting with flavor and your favorite nutrient. All of these soups have at least 15 grams of protein per serving, which will help keep you full and satisfied for longer. While you might think soup can take a lot of time to prepare, these filling, high-protein soups require just 20 minutes of active prep time, so you can have a delicious dinner that’s easy to make. Try our classic Sick Day Chicken Noodle Soup or our hearty Slow-Cooker Loaded Broccoli & Chicken Soup for…

The 2025 Sveriges Riksbank Prize for Economic Sciences in Memory of Alfred Nobel has been awarded to three researchers who have shown how technological and scientific innovation, coupled to market competition, drive economic growth.One half of the prize goes to economic-historian Joel Mokyr of Northwestern University in Evanston, Illinois, and the other half is split between the economic theorists Philippe Aghion of the Collège de France and the London School of Economics and Peter Howitt of Brown University in Providence, Rhode Island.“I can’t find the words to express what I feel,” Aghion said. He says he will use the money…

The leading expert on bone injuries in court cases on baby deaths has referred himself to the General Medical Council after a High Court judge accused him of having “a closed mind” and making “a number of repeated mistakes.”12In a High Court family division case last year, Mr Justice Keehan said that David Mangham was “currently the only forensic consultant histopathologist accepting instructions in cases of suspicious death and/or inflicted injuries in this country.” The judge added, “The consequences of this state of affairs, however, is that he has a huge workload.”Doubts over his evidence in criminal cases have since…

“In this photograph, I am taking local reporters out into Ohuira Bay on Mexico’s west coast, where my community’s sacred sites lie. We fish shrimp and crab here, and collect snail shells to make crafts — a tradition that has been part of our Indigenous culture for generations. I’m a member of the Lázaro Cárdenas Yoreme-Mayo community and work as a fisher, but collaborate with scientists to collect marine-life samples for testing. Recently, we’ve been collecting turtles for a nearby research centre to test for signs of contamination. Heavy metals such as cadmium, mercury and selenium have been detected, and…

Rhythmic stimuli presented to the ears, instead of the fingertips, help the brain synchronize to a musical beat. Image credit:©iStock, RangeechaHumans have an inherent ability to coordinate their movement to music—it’s no surprise that song and dance are so deeply embedded across cultures. But how does the type of stimulus, for example, whether it’s sound or touch, affect people’s ability to stay in rhythm?Recently, neuroscientists discovered that sound is better than touch when it comes to helping people keep the beat.1 Their findings, published in the Journal of Neuroscience, revealed that the different senses may not play equal roles in people’s…