Author: admin
From startups to giants in pharma and tools, the use of spatial biology is growing in importance in drug discovery. LatchBio, a four-year-old San Francisco builder of software and data infrastructure for biopharmas, on September 5 announced its release of a 25-million-cell atlas for spatial transcriptomics covering 45 tissue types, 63 diseases, and 11 spatial technologies—the largest open-source human spatial atlas to date, according to the company. Among pharmas, GlaxoSmithKline (GSK) applies Relation Therapeutics’ Lab-in-the-Loop platform, which integrates spatial and single-cell transcriptomics with tissue profiling, sequencing, and target validation—then combines those with multi-modal patient data, perturbational omics and translational cellular…
Senior Beauty & Lifestyle DirectorAlexandra Engler is the senior beauty and lifestyle director at mindbodygreen and host of the beauty podcast Clean Beauty School. Previously, she’s held beauty roles at Harper’s Bazaar, Marie Claire, SELF, and Cosmopolitan; her byline has appeared in Esquire, Sports Illustrated, and Allure.com.
Bethanie Carney Almroth, professor of ecotoxicologyDepartment of Biological and Environmental Sciences, University of Gothenburg, SwedenWe need to put humans and the environment before corporate profits, writes Bethanie Carney AlmrothPlastics have become a concern at the forefront of public environmental awareness campaigns and in political discussions. Nations of the world convened in Geneva, Switzerland, in August 2025 to negotiate a globally binding United Nations treaty intended to end plastic pollution across the full life cycle—from production to disposal.1 It had been three years since heads of state agreed on a mandate to create this historic treaty, but although the sixth round…
Characterizing how neuronal genomics change over time in healthy brains may help researchers better understand how aging affects cognitive function.Image credit:© iStock, BlackJack3DBiological aging undeniably affects human cognitive function.1 However, how this happens—the underlying factors, interactions, and processes—remains unclear. Michael Lodato, a geneticist from the University of Massachusetts (UMass), thinks somatic mutations—mutations that occur over an individual’s lifetime—play a key role in this phenomenon. In a study recently published in Nature, he and his research team conducted a detailed investigation of the genetic and genomic dynamics of the human brain across the lifespan, from infancy to centenarian.2 They found that…
Staphylococcus aureus is listed as a high-priority pathogen by the World Health Organization.Credit: Dennis Kunkel Microscopy/Science Photo LibraryAntimicrobial resistance (AMR) is projected to cause 39 million deaths worldwide over the next 25 years. But global efforts to find treatments for drug-resistant infections are not going to plan, according to two reports from the World Health Organization (WHO) released on 2 October1,2. The reports show that the global antibiotic drug-development pipeline is facing a dual crisis: a scarcity of drugs in development and a lack of innovation in methods to fight drug-resistant bacteria.“Antimicrobial resistance is escalating, but the pipeline of new…
Credit: Elva Etienne/Getty Images Research led by Beckman Research Institute of City of Hope shows that altered expression of the SMOC1 gene promotes a physiological change leading to higher blood sugar and decreased insulin expression and secretion in the body, as seen in type 2 diabetes. Writing in Nature Communications, the team explained that higher expression of SMOC1 led to insulin-producing beta cells in the pancreas transforming into glucagon-producing alpha cells. This is a phenomenon seen in people with type 2 diabetes leading to higher blood sugar levels, as glucagon acts to boost blood sugar and lower levels of insulin,…
Manjit Sareen reflects on the first Asia-Pacific Longevity Medicine International Summit and the launch of a global directory for clinics. There was a palpable sense of optimism in Hong Kong as experts from around the world gathered for the region’s first Longevity Medicine International Summit – a moment that signalled how far the field has come, and how much potential still lies ahead. The first-ever Asia-Pacific Longevity Medicine International Summit (APAC-LMIS) in Hong Kong marked an important milestone for the region – bringing together clinicians, researchers, innovators and industry leaders to advance the science and practice of longevity medicine. For…
Every beauty professional has their nonnegotiable steps. In our series, Like A Pro, we tap experts for the top three techniques they absolutely swear by. Here, you’ll hear from a variety of industry insiders on the fail-safe tricks they always keep in their back pockets. We’re all about simplifying your beauty regimen wherever you can, and sometimes the best routines are as easy as 1, 2, 3.
High cholesterol can increase your risk for heart disease.Experts say the number one afternoon habit to help lower your cholesterol is reaching for a fiber-rich snack.Fiber helps lower HDL cholesterol, fights inflammation and supports a healthy weight. Taking care of your heart is one of the best things you can do for your health. Heart disease is a leading cause of death among Americans and certain lifestyle factors—like high cholesterol—can increase your risk. Though high cholesterol can sometimes be genetic, what you eat makes a difference. If you’re looking for a simple way to lower your cholesterol, experts say the…
Creatine has long been popular in niche workout communities, but it’s getting more mainstream attention these days, and for good reason. “The benefits of creatine go well beyond just muscle and strength,” says Michael Ormsbee, PhD, director of the Florida State University Institute of Sports Sciences and Medicine in Tallahassee, Florida.“Creatine is a naturally occurring compound made from three amino acids — arginine, glycine, and methionine,” Dr. Ormsbee says. Your muscles store a form of creatine and use it to make adenosine triphosphate (ATP), your body’s main energy source during high-intensity, short-duration activities like sprinting or lifting, he explains.For high-intensity…