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When Kendall Toole left Peloton last summer, fans were stunned. She’d become one of the platform’s most beloved instructors, known for her energy and emotional honesty. But behind the scenes, Kendall was navigating something more complex than anyone realized: she’d outgrown the role she was playing.
If you’ve been putting off a root canal, you may want to schedule that appointment. That’s because new evidence suggests it could have protective health effects that go way beyond your mouth.A study found that successful root canal treatment was linked to improvements in blood sugar, cholesterol, and inflammation — all key factors in heart disease and diabetes risk.[1]“Our research shows that treating an infected tooth does far more than relieve pain. It can improve your overall health,” says lead author Sadia Niazi, PhD, a clinical lecturer in endodontology (the study of what’s inside of teeth) at King’s College London.Why Oral…
Credit: Roger Harris / Getty Images / Science Photo Library A new antibiotic called sorfequiline, a type of next generation diarylquinoline, has achieved good results for treating drug sensitive tuberculosis (TB) in combination with the antibiotics pretomanid and linezolid in a Phase II study. The trial results, which were presented at the by TB Alliance at the Union World Conference on Lung Health in Denmark this week, showed that the sorfequiline (also known as TBAJ-876) combination treatment performed better than a standard drug-sensitive TB combination treatment of isoniazid, rifampin, pyrazinamide, and ethambutol. Notably, the researchers also found sorfequiline had higher…
Beauty support from the insight out, this best-selling daily collagen powder supplies the body with the amino acids it needs to effectively produce healthy hair, firm skin, and strong nails.* Supported by hyaluronic acid, vitamin C & E, biotin, and L-glutamine, this formula checks all the boxes.* For a daily treat, gift them the decadent chocolate flavor, which is sweetened with organic monk fruit extract and organic cocoa powder.
Skeletalis initially targets osteoporosis with bone-targeted drug delivery designed to minimize systemic exposure. Precision medicine startup Skeletalis has secured an $8 million funding round to advance new treatments for musculoskeletal diseases. The funding is intended to advance the development of its small molecule osteoporosis drug candidate towards clinical trials. Solving musculoskeletal conditions is key to extending healthy longevity and sustaining functional independence in an aging population. Boston-based Skeletalis is initially focused on osteoporosis, a disease characterized by plummeting bone density. Alongside the progressive muscle loss known as sarcopenia, these conditions are key drivers of frailty and dependency, with osteoporotic fractures,…
Too much added sugar is linked with weight gain and risk of chronic diseases.Added sugar from beverages can add up quickly, with many popular drinks delivering more than 13 grams of added sugar. Swapping out your sugary drinks for healthier, lower-sugar options can help you keep your added sugar in check. Making smart food choices often means cutting down on added sugars, and for good reason. The Dietary Guidelines for Americans recommends limiting added sugars to less than 10% of your daily calories, which comes to about 50 grams, or 12 teaspoons, per day on a 2,000-calorie diet. While this might…
More than 400 military personnel who suffered side effects from the antimalarial drug mefloquine (Lariam) have finally reached a settlement with the UK’s Ministry of Defence (MoD) after a nine year battle by the 434 victims seeking compensation.The novel antimalarial drug was first tested in US troops serving in Vietnam in the 1970s. It was then approved for prophylactic use in malarial areas where there was known resistance to the antimalarial medicine chloroquine.1However, the neuropsychiatric side effects of the drug, both in civilians and military personnel, soon began to emerge. These included confusion, anxiety, nightmares, depression, hallucinations, and suicidal ideation.…
Researchers in China compared wild-type Lp20 (Lp20-WT)—a strain of the bacterium that possesses natural, functional copies of certain genes which provide high BSH activity—to a BSH1 knockout mutant, which exhibits significantly reduced or no measurable bile salt hydrolase (BSH) activity.They found the beneficial effects on high-fat diet-fed mice were only present in the wild type, providing “direct evidence of BSH’s anti-obesity effects through gene deletion,” they wrote in the journal Nutrients. “Specifically, BSH lowers cholesterol by modulating hepatic bile-acid metabolism-related gene expression and altering the gut microbiota composition,” they explained, noting that their results need further large-scale human validation. Global…
Get breakfast on the table fast with these make ahead mini quiches, muffin-tin omelets and egg bites. These handheld bites keep well in the fridge or freezer and are easily reheated for a delicious and filling breakfast. Recipes like our Mini Crustless Quiches with Kale, Mushrooms & Feta and our Sausage, Spinach & Mushroom Egg Bites are a tasty, customizable morning meal that everyone will love. Love these recipes? Join MyRecipes to save them all with one click. It’s so easy—and free! Mini Crustless Quiches with Kale, Mushrooms & Feta Photographer: Morgan Hunt Glaze, Food Stylist: Margaret Monroe Dickey, Prop…
You have full access to this article via your institution. Preparations begin for the G20 summit in Johannesburg, South Africa.Credit: Per-Anders Pettersson/GettyNext week, Johannesburg in South Africa will host a historic meeting of the G20, an annual forum of the leaders of the world’s major economies. This will be the first meeting of the G20 leaders to be held in Africa. It will also be the first that a member country — the United States — has declined to attend.Reducing inequality benefits everyone — so why isn’t it happening?The United States did attend preparatory meetings leading up to the G20,…