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Three scientists shared the 2025 Nobel Prize in Physiology or Medicine for their contributions to the field of immunology. Earlier today, it was announced that Mary E. Brunkow, PhD, Fred Ramsdell, PhD, and Shimon Sakaguchi, MD, PhD, received this year’s award for fundamental discoveries relating to peripheral immune tolerance. The laureates identified and elucidated the activity of CD4+CD25+FOXP3+ regulatory T cells (Treg cells), which launched the field of Treg cell-mediated peripheral immune tolerance and forms the basis of efforts to develop new treatments for autoimmune disorders, cancer, and other applications. The first key discovery was made by Sakaguchi in 1995,…

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Maneesh Jain is the chief executive and co-founder of biotechnology firm Mirvie.Credit: Mitch TobiasThe meaning behind our monikerMirvie is a biotechnology company in San Francisco, California, that is developing blood tests that can predict pregnancy complications. It hopes its RNA-based technology will offer a non-invasive way to identify those at risk of conditions such as preeclampsia and premature birth. It was co-founded by physicists and serial entrepreneurs Maneesh Jain, the firm’s chief executive, and Stephen Quake, the company’s scientific advisory board chair. Quake combines his role with a bioengineering research position at Stanford University in California. Mirvie came about, says…

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This postdoc studies the maternal brain to reveal how pregnancy and immune changes shape cognition and behavior.Image credit:©iStock, BannosukeQ | Write a brief introduction to yourself including the lab you work in and your research background. My name is Jessica Bradshaw. I am an immunologist in Rebecca Cunningham’s lab at the University of North Texas. We study how sex hormones and oxidative stress influence the brain across the lifespan. Our goal is to better understand how these factors shape memory, behavior, and risk for neurodegenerative disease in both men and women.Q | How did you first get interested in science…

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This week’s headlines included coverage the U.S. FDA declaring NMN lawful in dietary supplements, Danone’s unveiling of its new OneBiome lab, Iovate’s restructuring efforts, Haleon’s Bone Up campaign in China and Seed Health’s new Co-Biotics line.The U.S. Food and Drug Administration (FDA) has responded to a Citizen Petition from the Natural Products Association (NPA) and the Alliance for Natural Health USA (ANH) on the status of NMN, declaring the vitamin B3 form to be lawful for use in dietary supplements.In a letter signed by Donald Prater, DVM, principal deputy director for human foods, the FDA stated that it had revised…

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October brings a bounty of foods that are foundational to the Mediterranean diet.Pears, butternut squash, pomegranates and Brussels sprouts are all at their peak.Fall is also an ideal time to stock up on staples, like pecans, lentils and canned pumpkin. By October, cooler temperatures are here to stay. And so is a new harvest of root vegetables, winter squash, apples and pears. Adding these seasonal fruits and vegetables to your plate isn’t just delicious. It can also align perfectly with the Mediterranean diet, which has been shown to reduce the risk of heart disease, type 2 diabetes, metabolic syndrome, cancer…

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Prediabetic adults eating one mango daily showed better glucose control, improved insulin sensitivity, and reduced body fat than those eating a low-sugar granola bar. The mango had a higher sugar content of 32 g versus the 11 g in the bar.  The study by clinical nutrition researcher Raedeh Basiri, assistant professor at George Mason University, US, suggests that foods like mango are less important for prediabetic adults than the overall nutritional context. Tropical fruits contain between 10 and 50 g of sugar.Published in Foods and conducted over six months, the study is dubbed “the first” long-term clinical trial to show metabolic…

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Picture this: You toss a banana, a few frozen berries and a splash of juice into a blender. Minutes later, you’ve got a refreshing smoothie that feels like a healthy start. For a while you’re satisfied—until you’re digging through your bag for a granola bar because you’re suddenly starving. Sound familiar? The problem isn’t your intentions—it’s the recipe. “Fruit-based smoothies are mostly carbohydrates which digest more quickly and can leave you less full than protein and fat,” explains Bridget Cassady, Ph.D, RDN, LD, a registered dietitian. In other words, you’ve basically made yourself a blended fruit salad. The biggest mistake?…

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