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Since their first descriptions in the 17th century, cells have fascinated scientists, despite being invisible to the naked eye. When virologist Joe McKellar began studying influenza viruses and cellular restriction factors during his doctoral studies at the French National Center for Scientific Research, he found himself drawn to the microscope. These human liver cancer cells, when grown on Poly-L-Lysine coated glass, become flattened and send out wild, spiky actin protrusions. Joe McKellar, Institute of Molecular Genetics of Montpellier, French National Center for Scientific ResearchPeering through its eyepieces, he quickly became captivated by the world of imaging. “It got me interested…

I watched the 2024 Wicked movie shortly after it began streaming. The timing was perfect—I was days into my first run-in with Coronavirus and was the sickest I had been in years. My body was weak, and I, quite honestly, was depressed and desperate to relieve COVID symptoms. A nearly three-hour movie filled with whimsy was exactly what I needed to bring some life back to my soul. Strong characters, like Glinda and Elphaba, and thoughtfully built worlds tend to evoke that in people. And honestly, Le Creuset Dutch ovens do just the same for many (me included). It makes…

engineer using digital tablet working late night shift at petroleum oil refinery in industrial estate. Shift work could put people at risk of developing kidney stones, according to researchers who say that these types of occupations should be targeted for lifestyle interventions. The risk of kidney stones was particularly great for those who worked nights, report by Man He, from Sun Yat-sen University, Guangzhou, China, and colleagues in the Mayo Clinic Proceedings. It was also greater for younger people and lower with longer durations of shift work, possibly because adjusting and adapting to shift work results in healthier lifestyles that…

The Healthy Ageing Think & Do Tank, led by EIT Food, unites 45 experts from 15 countries to help the food system adapt to support an increasingly older European population. These researchers, food innovators, health professionals, and policy experts will drive innovation and develop solutions that support healthier aging through food. The independent group develops practical, science-based solutions to promote well-being, prevent diet-related diseases, and empower people to maintain autonomy as they age. “The European population is aging rapidly, and this brings both challenges and unique opportunities,” says Begoña Pérez-Villarreal, director of EIT Food South. “By combining culture, science, and community,…

Moist, tender pumpkin bread is perfect for fall and uses the entire can of pumpkin puree.This bread is loaded with antioxidants and fiber from the pumpkin and whole-wheat flour.You can replace the pumpkin puree with sweet potato puree, and it will be just as delicious. We all need that one great recipe for certain classics, and this really is the only Pumpkin Bread recipe you’ll need. Antioxidant-rich pumpkin puree is infused with warm cinnamon, pumpkin pie spices and vanilla. We use half whole-wheat flour, which bumps up the fiber content without turning the loaf too dense. And you’re going to…

However, sometimes, when one person takes a timeout, the other person feels abandoned. To de-escalate relationship conflict, try to truly become a team player with your partner. Get clear on the fact that you’re in this together, neither of you is perfect, and you’re both going to get reactive sometimes. 

The benefits of doing science can feel abstract, but a new tool can trace how research projects had broad societal impacts on policies, medicines or products.Credit: Daniel Leal/AFP via GettyScientific research offers many benefits to society, but how do you trace the impact of specific projects? It’s easy to track which papers result from a grant, but much harder to follow how research has broader societal impacts on policies, medicines or products.“Those are much more exciting [impacts], and provide greater public good,” says Dashun Wang, director of the Center for Science of Science and Innovation at Northwestern University in Evanston,…

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When the pioneering artificial intelligence (AI) firm Google DeepMind announced almost two years ago that it had used a deep-learning AI technique to discover 2.2 million new crystalline materials, it seemed to herald a thrilling new era of accelerated materials research1.Composed of elements from across the periodic table, the materials in the trove included 52,000 simulations of layered compounds similar to the wonder material graphene, 528 potential lithium-ion conductors that might be used to improve rechargeable batteries, and much more.Researchers built an ‘AI Scientist’ — what can it do?But the effort — and similar ones that followed, involving the technology…

Scientists headed by a team at the University of Cambridge, University College London, the Francis Crick Institute, and Polytechnique Montréal have, for the first time, directly visualized and quantified the protein clusters that are believed to trigger Parkinson’s disease (PD). The team developed an imaging technique, Advanced Sensing of Aggregates–Parkinson’s Disease (ASA–PD), that allowed them to see, count, and compare in post-mortem brain tissue the protein assemblies, known as oligomers, which are proposed as early drivers of pathogenesis of Parkinson’s disease. The new development, one of the team noted, is “like being able to see stars in broad daylight.” Describing…