Author: admin

Credit: jxfzsy / iStock / Getty Images Plus A digital stethoscope enhanced by artificial intelligence (AI) has shown to more than double the sensitivity of a traditional stethoscope when detecting moderate or severe valvular heart disease. These findings were published today in the European Heart Journal – Digital Health. “Valvular heart disease is unfortunately very common among older adults, yet it often goes undetected until symptoms become advanced,” said Rosalie V. McDonough, MD, senior manager of medical affairs at Eko Health. “This means that patients can experience complications and worsening health which could have been prevented with earlier diagnosis.”  More…

The DNA-based vaccine induces antibodies to the HIV antigen (blue) without eliciting antibodies to the DNA particle (gray), whereas the protein-based vaccine generates antibodies to both the HIV antigen (blue) and the protein particle (red). Image created by Grant Knappe (MIT) based on atomic models from MIT (DNA-based vaccine) and Scripps Research (protein-based vaccine). [MIT and Scripps Research] If you zoomed in far enough on a new experimental HIV vaccine, you wouldn’t see the usual protein shell that most vaccines rely on. Instead, you’d find tiny geometric structures folded from strands of DNA—molecular origami designed not to be noticed at…

Credit: ALFRED PASIEKA/SCIENCE PHOTO LIBRARY/ Getty Images An AI tool that can accurately apply information gleaned from unlabeled brain magnetic resonance images (MRIs) to diverse clinical tasks and could transform neurological care. The generalizable foundation model BrainIAC, outlined in Nature Neuroscience, provides a powerful foundation on which to develop imaging-based deep learning tools that could be used in a clinical setting. BrainIAC was able to learn from large, unlabelled data—which are far more widely available than annotated, task-specific datasets—but could also use very limited training data in several clinical settings. It outperformed publicly available foundation models in several areas, from brain…

Ambr founder on how the startup is targeting population health with a prevention platform powered by ‘explainable AI.’ Norwegian healthtech startup Ambr has joined the global race to leverage AI to help move healthcare from its current reactive model to one based on proactive prevention. With age-related and chronic diseases accounting for the vast majority of healthcare spending and hospital deaths, the company’s pitch is that better prediction, clearer explanation and deeper patient engagement can help support doctors in the shift from treating illness to managing long-term health. Ambr’s “explainable AI” platform, which integrates clinical data, biomarkers, lifestyle information and…

Credit: Kateryna Kon/Science Photo Library/Getty Images Widespread vaccination against human papillomavirus (HPV) has already reshaped the prevention landscape for cervical cancer. Now, a new modeling study from the University of Oslo suggests it may be time to rethink one of the most entrenched pillars of cancer prevention: how often vaccinated women need to be screened. In a paper from Annals of Internal Medicine based on a large-scale decision analytic model, researchers show that women who received the HPV vaccine—especially at younger ages—could safely undergo cervical cancer screening far less frequently than current guidelines recommend, without sacrificing health benefits. In some…

Have you noticed how people in their 20s and 30s are increasingly managing health issues once associated with much older generations?  Specialized diets, daily medications, wearable health trackers, and regular visits to specialists like endocrinologists or rheumatologists have become surprisingly common among young adults.  This shift raises an important question: are we exaggerating the problem, or is there truly a rise in chronic illnesses in young adults in the US? Unfortunately, the evidence points to a very real and troubling trend. Chronic illness in young adults is no longer a rare exception—it is becoming a defining public health issue.  Medically,…

When it comes to optimizing your health, fish oil is one of the most researched and recommended supplements in the world. From heart health and cognitive function to reducing inflammation in athletes, the benefits are well-documented. However, the most frequent question clinicians and nutritionists face isn’t whether you should take it, but how much fish oil per day is actually necessary to see results. Dosage is where most people get confused. You might see a bottle labeled “1000 mg,” but that number rarely tells the whole story. The effectiveness of your supplement depends less on the total weight of the…

Since the landmark 2019 approval of Enhertu, the antibody-drug conjugate (ADC) drug that quickly became a blockbuster breast cancer therapy—with global sales surpassing $1.6 billion in 2022—industry investment in ADC technologies has surged. ADCs marry the precision of antibody targeting with the tumor-killing power of cytotoxic drugs, offering a compelling strategy for delivering potent therapies directly to diseased cells. Enhertu chemically links deruxtecan, a topoisomerase I (topo I) inhibitor, to trastuzumab, a monoclonal antibody that selectively binds HER2—a protein essential for normal cell growth but overexpressed in many breast cancers. Topo I inhibitors are highly effective at destroying rapidly dividing…

Credit: Mohammed Haneefa Nizamudeen/Getty Images Lymph node assessment should be expanded in patients undergoing surgery for non-small-cell lung cancer (NSCLC) to more accurately detect hidden systemic disease, suggests research presented at the 2026 Society of Thoracic Surgeons Annual Meeting. The study “represents the largest analysis to date examining the real-world outcomes of patients with varying extents of lymph node dissection,” said study author Christopher Seder, MD, a thoracic surgeon at Rush University Medical Center in Chicago. “Our findings suggest that in clinical node-negative NSCLC, assessment of more than one N1 nodal station, including station 12-14 lymph nodes, is associated with…

Some types of CD8+ T cells (killer T cells) may play a role in the development of multiple sclerosis (MS). This is according to data from a new study published in Nature Immunology. Specifically, scientists found specific T cells that are abundant in people with MS, which also target the Epstein-Barr virus (EBV). They suggest that this points to a possible role for the virus in triggering the immune response seen in the autoimmune disease.    Full details are published in a paper titled “Antigen specificity of clonally enriched CD8+ T cells in multiple sclerosis.” For Joe Sabatino, MD, PhD, senior author on the study and an assistant professor of…