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An mRNA vaccine suppressed neovascularization—a condition caused by age-related macular degeneration (AMD), a leading cause of vision loss for elderly people—in the retina of mouse models. The vaccine can be delivered intramuscularly and offers a more comfortable and easier-to-administer alternative for treating AMD and other neovascular eye diseases. This research is published in Vaccine in the paper, “mRNA vaccination mitigates pathological retinochoroidal neovascularization in animal models.” AMD is one of the leading causes of vision loss in people over 60 years; the condition affects nearly 200 million people worldwide. One form of the disease, known as wet AMD, is caused…

Like counting sheep at bedtime, Countable PCR empowers scientists to accurately count nucleic acid molecules one by one.Image credit:©ISTOCK, Sudowoodo DNA and RNA are central to laboratory and clinical research, where quantifying their abundance is key to applications such as gene expression analysis, cell and gene therapy development, and circulating tumor DNA detection. To obtain these measurements, researchers and clinicians use several methods, including quantitative PCR, digital PCR, and next-generation sequencing. However, these approaches provide only estimated values based on ambiguous amplification curves, complicated statistical approximations, or complex computational reconstructions. This uncertainty reduces scientists’ confidence in the resulting measurements.To improve…

Be the first to rate & review! Sweet beets get a flavor boost from roasted garlic in this simple side dish. As the beets roast in the oven, a whole head of garlic roasts alongside them. Mashed with a touch of melted butter and fresh herbs, the garlic coats each bite with savory flavor. You can make this recipe with red beets, golden beets or a colorful mix for a vibrant presentation. Easy enough for weeknight cooking but special enough for a holiday spread, this recipe is a delicious way to showcase the earthy root vegetable. Published on September 30,…

Credit: Mohammed Haneefa Nizamudeen / iStock / Getty Images Plus A new international study led by Mayo Clinic researchers has identified a genetic factor that may explain why some patients with colorectal cancer that has spread to the liver experience more severe liver damage after chemotherapy. In their study, published in The Lancet eBioMedicine, the team showed the a single nucleotide polymorphism (SNP) in the PNPLA3 gene is associated with a heightened risk of chemotherapy-associated liver injury (CALI) in patients receiving neoadjuvant chemotherapy for colorectal cancer liver metastases (CRLM). “This is the first study to clearly show that a genetic…

The study identified 60 metabolites and the metabolic patterns associated with vitamin D deficiency (VDD) in early pregnancy, providing new proof of vitamin D’s beneficial effect on pregnant women’s lipid levels and offering insights into the underlying mechanisms. Published in Nutrients, the study identified metabolite changes unreported in earlier investigations. Specifically, VDD was linked with upregulated benzenoids, organic acids and organic oxygen compounds, suggesting it may disturb aromatic compound metabolism and broader energy-related pathways.“This study provides new metabolomic evidence for the linkage between vitamin D and maternal lipid levels during pregnancy, along with clues about the mechanisms,” the report stated.Vitamin…

Inflammation and high blood sugar often travel together. Choosing healthy, low-carb drinks may help manage both of these issues.Green tea, golden milk, coffee, dairy milk and 100% veggie juice are all great choices. Inflammation is the wellness buzzword of the moment—and for good reason. Chronic inflammation can increase your odds of developing a variety of illnesses like heart disease, cancer and type 2 diabetes. What’s more, for people with diabetes, ongoing inflammation can also make managing diabetes difficult, as inflammation makes it harder for the body’s cells to use insulin.  While eating plenty of anti-inflammatory foods is key for curbing inflammation,…

As the global nutrition and wellness landscape continues to evolve, 2026 looks to be a year defined by nutrition innovations across a vast range of categories. However, some trends stand out from the rest, both in their veracity and potential market opportunities. Consumers continue to seek products that deliver tangible health benefits, align with ethical and environmental values, and offer convenient, science-backed solutions for daily well-being.From next-generation functional ingredients and plant-forward formulations to personalized solutions and adaptive nutrition, brands must respond to the demands for smarter and more holistic approaches to health.Ahead of our upcoming webinar, “Top Nutrition Trends 2026,”…

A 2-in-1 inhaler treatment is more effective than salbutamol for preventing asthma attacks in children aged 5 to 15 and is similarly safe, a randomised controlled trial has reported.1A combined treatment of the inhaled corticosteroid budesonide and the fast acting bronchodilator formoterol reduced children’s asthma attacks by an average of 45% compared with the commonly used salbutamol inhaler, the study published in the Lancet found.Experts said that the study, the first to investigate the use of a 2-in-1 inhaler as the sole reliever therapy for children aged 5 to 15, could prompt a change in clinical practice for the condition…

From TikTok videos touting mouth tape and weighted blankets, to magazines ranking insomnia-curbing pillows, sleep advice is everywhere. And it’s no wonder. People all over the world complain of insomnia and not getting enough sleep, driving a market for sleep aids worth more than US$100 billion annually.But scientists warn that online hacks and pricey tools aren’t always effective. And failed attempts to remedy the situation could have negative effects, says Andrew McHill, a circadian scientist at Oregon Health & Science University in Portland. “It could discourage people from finding help, and things could get worse,” he says.How the brain wakes…

Engineer John Logie Baird used ventriloquist dummies in early experiments of his invention: the television.Credit: Hulton-Deutsch Collection/Corbis via GettyLong before modern technology, the principle of the common good existed. It was not born with society itself, but later, with an awareness that if it were neglected, a society might collapse.Principles that promote social cohesion and well-being are found in most cultures. Early examples include the millennia-old Code of Hammurabi, which punished certain liars with a humiliating haircut1, and ancient Biblical law, which required landowners to leave part of their harvest for orphans, widows, foreigners and poor people.Supportive? Addictive? Abusive? How…