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Credit: Steve Gschmeissner / Science Photo Library / Getty Images You’ve all seen the videos—the heart-melting, tear-jerking ones where a deaf child is sitting in a doctor’s office as their cochlear implant is turned on for the first time. Almost immediately, their eyes light up, parents start crying—you start crying. Lawrence R. Lustig, MD, professor and chairman of otolaryngology, head, and neck surgery at Columbia University Medical Center and New York Presbyterian Hospital, has witnessed this remarkable experience many times. That isn’t what happens with the deaf children who received DB-OTO, a gene therapy developed by Regeneron that aims to…

Freeze-drying, also known as lyophilization, is invaluable for stabilizing sensitive compounds like probiotics that need to survive the journey to the gut. Pebley explained that this ancient preservation method removes moisture without damaging cellular structure or nutrients.“And that’s what the Inca Indians did,” Pebley said. “They harvested their vegetables, took them up to Machu Picchu or 22,000 feet. The air is less, it’s somewhat of a vacuum. And over a long period of time, those vegetables freeze-dried and they were shelf-stable then at that temperature and atmosphere, as long as there wasn’t moisture absorbing into them.”He added that OFD Life…

Researchers have developed a new supplement combining iron, prebiotics, and probiotics. In their trials, the formula restored blood iron levels in anemic mice without triggering inflammation or disrupting the balance of the gut microbiota. To treat iron-deficiency anemia, clinicians typically prescribe oral iron supplements. However, these can leave behind excess iron that causes inflammation and an upset stomach, the team highlights.“By advancing biomaterial-based iron delivery, this research offers a transformative approach to address anemia, directly contributing to improved nutrition and long-term public health,” says study co-author Poonam Sagar.Iron deficiency anemia commonly causes tiredness, headaches, or shortness of breath. However, only…

Kamran Abbasi, editor in chiefThe BMJkabbasi{at}bmj.comHow far will you go to promote your medical invention? This is a question for clinical innovators. How far will you go to market the invention? This is a question for corporations whose primary purpose is to keep pleasing their shareholders. The limits of promotion, of course, should be reached when the balance of benefits and harms is no longer favourable. That balance is a judgment, made by people capable of deciphering the evidence and seeking to protect the public—drug and device regulators, for example.What happens when an intervention seems innocuous, the data are equivocal,…

With just one pot, pan or skillet, you can have a delicious dinner on the table without a sink full of dishes. These healthy meals have been saved thousands of times by users on MyRecipes, and now you can save them all to your own curated collection with just one click. From our 5-star High-Protein Lemon Chicken Orzo to our easy 20-Minute Black Bean Soup, save these recipes to try next time you’re in the mood for a delicious dinner that feels effortless. Love these recipes? Join MyRecipes to save them all with one click. It’s so easy—and free!  High-Protein…

Register Now Panelists: Shahram Misaghi, PhD Research Fellow, Cell Line DevelopmentProlific Machines View Bio Panelist Shahram Misaghi, PhD Shahram Misaghi, PhD, is a research fellow at Prolific Machines where he leverages his deep research and biological systems expertise to help shape the optogenetic company’s cell line development (CLD) capabilities. He is a research leader with over two decades of extensive work in biomanufacturing stable and inducible systems, from which he has demonstrated and published the impact of chemical inducible gene expression applications in CHO CLD. Prior to Prolific, he worked in Genentech’s CLD Group for 18 years. He has 52…

Credit: stevanovicigor/ Getty Images Researchers at the University of Zurich have developed a new artificial intelligence-enhanced version of the GRACE (Global Registry of Acute Coronary Events) scoring system that provides a personalized and accurate method for assessing coronary risk of patients with non-ST-elevation acute coronary syndrome (NSTE-ACS). Published in The Lancet Digital Health, the new findings revealed by the development of GRACE 3.0 suggest that current approaches to treatment stratification for NSTE-ACS may be misclassifying patients and could be improved by leveraging individualized treatment effect predictions. “GRACE 3.0 is the most advanced and practical tool yet for treating patients with…

Cancer immunotherapy enhances the body’s natural ability to fight cancer, but it doesn’t work for every patient. Researchers are looking for ways to better predict and improve immunotherapy outcomes.Image credit:©iStock, FatCameraIn 2018, James Allison and Tasuku Honjo received the Nobel Prize in Physiology or Medicine for their co-discovery of molecular “brakes” that could be released to enhance the immune system’s response against cancer. Their recognition helped immunotherapy gain traction and revolutionized cancer treatment. However, patients’ responses to cancer immunotherapy can vary widely, and many factors influence these—from genetics to the consumption of artificial sweeteners. In this article, learn about some…

These quick, high-protein dinners come together in three steps or less, making healthy weeknight cooking simple and stress-free.Each meal packs at least 15 grams of protein from sources like chicken, beans, eggs and salmon to help keep you strong.With flavorful recipes from one-pot orzo to teriyaki stir-fry, this plan keeps dinner exciting and balanced all week long. It’s no secret that many of us are pretty focused on protein. This nutrient is responsible for supporting everything from your muscles to your immune system. And this week’s dinners, which come together in three steps or less, take the guesswork out of…

Here’s what you might eat in a single day on the diabetes exchange diet.Pick Whole Over Refined Grains at BreakfastA typical breakfast might include:A poached eggA serving of fresh fruit, such as half a grapefruitTwo slices of toast with 1 tsp spread and 8-oz glass of skim milkAnother option could be:1 1/2 cup whole-grain, unsweetened breakfast cereal1/2 cup sliced fruit1/4 cup unsalted nuts, like almonds1 cup skim milkGo for Lean Protein at LunchLunch could be:A whole-wheat turkey sandwich3/4 oz of pretzelsA side salad topped with fat-free dressing3/4 cup sliced fruitUse low-sodium, skinless turkey or chicken breast, or drained canned light…