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MethodsThis systematic review is reported according to the Transparent Reporting of multivariable prediction models for Individual Prognosis or Diagnosis for Systematic Reviews and Meta-Analyses (TRIPOD-SRMA) guideline16 (see supplementary table 1) and the reporting guidelines of the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) (see supplementary table 2), including the extensions for abstracts and literature searches (PRISMA-S) (see supplementary tables 3 and 4).1718 The protocol is available online. The protocol underwent some amendments. At the time of protocol registration, we planned to include only models with at least three predictors. During the screening phase, we opted to track models…

NeuroString—a high-density soft bioelectronic fiber for multimodal sensing and stimulation—is as thin as a human hair. This fiber tip has 32 channels, built for long-term mouse brain implantation to monitor neural activity over months. [Muhammad Khatib] When Muhammad Khatib, PhD, a Palestinian raised in Israel, now working at Stanford University as a postdoc, described his research to Inside Precision Medicine, there was a peaceful, restrained urgency behind his words. “I care a lot about human suffering,” Khatib said. “I want to use my expertise and skills to find ways to minimize it.” That mission has propelled Khatib from his hometown…

Researchers have analyzed Taylor Swift’s accent in interviews.Credit: Gareth Cattermole/TAS24/Getty Images for TAS Rights ManagementResearchers have confirmed what Taylor Swift fans have long suspected: the music megastar’s dialect and pitch have shifted throughout her career.In the early stages of Swift’s music career, while she was living near Nashville, Tennessee, her speech had the hallmarks of a southern US accent. When she released her pop album Red in 2012, the southern twang had faded, suggest researchers who have analysed her voice1. It changed again when she moved to New York City, they say.A person’s dialect is typically associated with the region…

The company promoted its branded ingredient with an exhibition stand at the Allianz Arena in Munich during the opening game of the German football league earlier this month, showcasing German brand Natsana’s K2VITAL-containing Natural Elements range.“This initiative is part of Balchem’s latest marketing strategy, which aims to raise consumer awareness of the health benefits vitamin K2 has to offer, bridging the gap between B2B and B2C markets,” the firm said.Balchem announced its partnership with FC Bayern Women earlier this year to educate consumers about the importance of vitamin K2 and communicate the quality standards associated with K2VITAL. “Women’s sports are…

New research reveals how different tissues age at different rates, opening possibilities for targeted healthspan interventions. Aging is neither uniform nor orderly, yet most biological clocks attempt to distill it into a single figure – neat, marketable and often misleading. A study led by researchers at Yale University and now reported in Nature Aging proposes an alternative: a single blood test capable of estimating biological age across multiple organ systems, revealing that our hearts, kidneys, brains and lungs often march to very different rhythms. Earlier work using proteomic panels had hinted at such organ-level differences, but required costly multi-assay testing;…

New clinical research supports that consuming Arla Foods Ingredients’ Lacprodan ISO.WaterShake before meals can help control blood sugar in pregnant women with gestational diabetes mellitus (GDM). The ingredient is a 100% whey protein isolate for clear beverages, which is formulated to remove unpleasant aftertastes in hydrating sports drinks and flavored waters. Arla Foods Ingredients partnered with the Danish Aarhus University and the Steno Diabetes Center to investigate the effects of whey protein on GDM.The study supports that 20 g of Lacprodan ISO.WaterShake before a meal reduces post-meal blood glucose peaks by -1 mmol/L (-18 mg/dl) in those with GDM and…

Catalent opened its new global corporate headquarters in Tampa, FL. Earlier this year, the company announced it would relocate from its previous headquarters in Somerset, NJ, and open a corporate office in Bridgewater, NJ, and a new corporate headquarters in Tampa. The move to Tampa reflects a strategic expansion in Florida, where the company has a long-standing presence through its 500,000-sq-ft site in St. Petersburg, which has more than 630 employees and serves as the company’s primary softgel development and manufacturing facility in North America, according to Alessandro Maselli, president and CEO. “For nearly half a century, we have enjoyed a…

A Mediterranean diet plus supplements were linked to better cholesterol levels in peri- and menopausal women.Study participants benefited from taking omega-3 fatty acid and plant sterol supplements.Results are promising but early—larger, longer studies are still needed for confirmation. A small pilot study suggests that pairing a Mediterranean diet with supplements containing phytosterols and omega-3 fatty acids may help improve cholesterol and reduce body fat in menopausal women. The research published in Frontiers in Nutrition, followed menopausal and perimenopausal women who adapted a Mediterranean-style eating plan and added two daily supplements. One was a phytosterol-based formula containing bergamot, prickly pear extract…

What screams fall more than butternut squash? This collection highlights this healthy winter squash in comforting soups, satisfying salads, creamy pasta and more. Try dishes like our Melting Butternut Squash with Maple Butter for a flavorful and nutritious side dish, or make our Spinach & Artichoke–Stuffed Butternut Squash in just 15 minutes of active time for a hearty dinner that brings out the best in this delicious vegetable. Love any of these recipes? Join MyRecipes to save, search and organize your EatingWell recipes all in one place. It’s free! Melting Butternut Squash with Maple Butter Photographer: Jen Causey, Food Stylist:…

Advances in recombinant technologies and validation standards equip researchers with confidence in biomarker discovery, detection, and translation.©iStock, quantic69Biomarkers found within the human body can help reveal valuable insights into health and disease. In the realm of cancer research and oncology, tumor biomarkers can support early detection, prognostic stratification, and therapeutic guidance; however, establishing a potential cancer biomarker as a robust enough indicator for widespread adoption can be a challenging endeavor.1 Scientists must overcome several common roadblocks, including validation in clinically relevant samples, on the path to transforming an initial laboratory finding into a widely accepted research or clinical tool.2 Recombinant…