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Researchers increasingly seek a quick, efficient, and cost-effective solution to genome sequencing that helps them overcome workflow bottlenecks and resource constraints.Image credit:©iStock, PobytovDNA sequencing technology has become a laboratory staple, helping scientists advance genomics research by leaps and bounds. However, analyzing vast amounts of genetic material often leads to bottlenecks that can impede downstream workflows and data acquisition.Ultima Genomics’ UG 100 Solaris™ is a high-throughput sequencer that helps researchers overcome speed and efficiency setbacks. “Solaris technology provides the opportunity to do a sequencing run that produces over 10 billion sequencing reads,” said Jay Therrien, Ultima Genomics’ chief commercial officer. “When we…

3 Vitamin Deficiencies That Cause NosebleedsNot getting enough of these key essential vitamins can lead to a variety of physical health symptoms, including weakened blood vessels and nosebleeds.1. Vitamin KVitamin K is an enzyme that is important for blood clotting (the process of stopping the flow of blood by clot formation), which is critical for healing damaged blood vessels. If you have a vitamin K deficiency, it might be difficult to stop bleeding from ruptured vessels, including nosebleeds.Besides increased risk of nosebleeds, other signs of vitamin K deficiency include easily bruised skin and muscles, bloody stool, and pale skin. Foods…

Sugar substitutes add sweetness with little effect on blood sugar, helping manage blood sugar levels.Natural options like stevia, monk fruit and allulose are low-calorie and gentle on blood sugar.Artificial sweeteners like sucralose and aspartame can be safe in moderation but may affect gut health. Blood sugar is a hot topic in the nutrition world—and for good reason. About 100 million Americans have prediabetes, which means they have elevated blood sugar levels that are not quite high enough to be classified as diabetes. Another 38 million people in the U.S. are living with diabetes. Whether you’re managing a diagnosis or aiming…

Working out is so important for our physical and mental health. A “good” workout looks different for everyone, and can range anywhere from a hot yoga class to running a marathon. No matter how you choose to move your body, it’s imperative that you set yourself up for success with the proper gear. Fortunately, we found exercise essentials on sale at Athleta. From “buttery” soft leggings to sweat-wicking shirts, pieces start at just $12.   Best Athleta Workout Clothes and Accessories on Sale  All About Tipping Large Belt Bag  Athleta A belt bag is a convenient way to keep track of…

Founded by entrepreneur Balazs Farkas-Jenser, Vivorum is built on the philosophy that sleep is the foundation of mental wellbeing and physical regeneration.With this in mind, ‘Cellular Renewal’ includes ingredients that not only support cellular health and beauty from within but also those which address sleep latency, night awakenings, mood and stress. “We only have one product at this stage, but our philosophy and our approach reach beyond that,” Farkas-Jenser told NutraIngredients. “We’re fixing the fundamentals, including sleep, mood and longevity on a cellular level, enabling the body to use the biological pathways that enable healthy cell regeneration.”The cellular supplement marketCellular…

Expression of ncAA bearing proteinsChemically competent E. coli K12 cells were co-transformed with pBAD_POI (encoding the POI with a C-terminal H6 tag) and pEVOL_PylRS (encoding two copies of the PylRS variant and tRNACUA). After recovery in 1 ml SOC medium for 1 h at 37 °C, cells were cultured in 5 ml of 2-YT medium supplemented with ampicillin (100 µg ml−1) and chloramphenicol (50 µg ml−1) and grown overnight at 37 °C. The overnight culture was then diluted to an OD600 of 0.05 in either 2-YT or AI media52 supplemented with ampicillin (100 µg ml−1), chloramphenicol (50 µg ml−1) and ncAA. Cells grown in 2-YT medium were grown to an OD600 of 0.6…

Leakey, L. B. New fossil skull from Olduvai. Nature 184, 491–493 (1959).Article  ADS  Google Scholar  Leakey, L. B., Tobias, P. V. & Napier, J. R. A new species of the genus Homo from the Olduvai Gorge. Nature 202, 7–9 (1964).Article  ADS  CAS  PubMed  Google Scholar  Tocheri, M. W., Orr, C. M., Jacofsky, M. C. & Marzke, M. W. The evolutionary history of the hominin hand since the last common ancestor of Pan and Homo. J. Anat. 212, 544–562 (2008).Article  PubMed  PubMed Central  Google Scholar  Plummer, T. W. et al. Expanded geographic distribution and dietary strategies of the earliest Oldowan hominins…

Researchers at King’s College London, UK, have published the “first-ever” evidence-based dietary guidelines for adults with chronic constipation. It includes kiwifruits, rye bread, high-mineral-content water, and supplements like psyllium fiber, magnesium oxide, and certain probiotic strains. The more common and widely recommended approaches to this bowel issue are too generic — eat high-fiber diets — or lack strong evidence of effectiveness for senna supplements, a type of laxative, note the researchers. Additionally, they critique common clinical guidelines for being limited and sometimes outdated with dietary recommendations, which typically focus on increasing dietary fiber and fluid intake.The guidelines published in the Journal…

New research led by scientists from the RIKEN Center for Brain Science points to astrocytes as the brain cells responsible for long-term learning and memory. In a new Nature paper, they demonstrate how emotionally intense experiences like fear in mice make their mark on small groups of astrocytes for several days, allowing them to re-engage when the mice recall the experience. Full details are provided in the paper titled “The astrocytic ensemble acts as a multiday trace to stabilize memory.” According to the paper, the team led by Jun Nagai, PhD, a principal investigator at RIKEN, investigated the activity of…

McGill study shows digital cognitive exercises can rejuvenate brain chemistry linked to memory and attention. For years, the idea that a digital ‘brain game’ could do more than mildly entertain or pass the time between Wordle rounds has been met with polite skepticism. Yet a new study from McGill University’s Montreal Neurological Institute – The Neuro – has revealed that targeted, computer-based brain exercises can do something no medication has yet achieved: restore the brain’s acetylcholine system, which underpins attention, memory and learning, to a level typically seen in people a decade younger. The INHANCE clinical trial, published in JMIR…