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Confocal imaging allows scientists to study cellular structures and tissues with the help of pinhole apertures, optical sectioning, and image reconstruction.©iStock, AndreasKermannSince its inception, confocal microscopy has enabled scientists to visualize and analyze fixed and live cells, as well as subcellular structures, with greater precision and clarity than conventional microscopy. This article explores the history of confocal microscopy, as well as its working principles, types of confocal techniques, major experimental considerations, and wide-ranging confocal microscopy applications.What Is Confocal Microscopy?Confocal microscopy is a specialized fluorescence imaging technique that scientists use to acquire images at greater resolution than conventional microscopy.1 In addition…
Healthy Weight–Gain Serving SuggestionsIn general, you need only 200 to 500 extra calories daily for safe weight gain, says Stephanie Kay, a registered holistic nutritionist in Ottawa, Ontario, Canada.A 1-cup serving of oatmeal made with water and topped with 1 tbsp of peanut butter provides roughly 250 calories. So, eating this as a snack in addition to the number of calories your body uses for energy each day might be enough to help you reach your goals.If you want to get 200 to 500 more calories than you’d typically need per day, but you’re not sure what total number to aim…
Melatonin did not make the cut.
Great chicken soup balances rich broth, tender chicken and flavorful extras.These celebrity recipes vary widely in style, complexity and cooking time.Bobby Flay’s dumpling soup was the crowd favorite for its texture and heartiness. Last weekend, I invited a group of friends (from three different families) over for a chicken soup tasting party, which I had dubbed “The Great Chicken Soup Showdown” in my head. Armed with scorecards and spoons, we sampled five celebrity chicken soup recipes side by side, and the results were surprising. This was also the moment I realized I probably own more soup bowls than is normal. …
Registered Dietitian NutritionistMolly Knudsen, M.S., RDN is a Registered Dietician Nutritionist with a bachelor’s degree in nutrition from Texas Christian University and a master’s in nutrition interventions, communication, and behavior change from Tufts University. She lives in Newport Beach, California, and enjoys connecting people to the food they eat and how it influences health and wellbeing.
All about the gut-skin-brain axis.
A GP who was convicted of attempted murder after posing as a community nurse to inject his mother’s partner with a toxin has been struck off the UK medical register.Thomas Kwan, 54, sent Patrick O’Hara false NHS letters pretending to set up an appointment for a covid-19 booster, a medical practitioners tribunal heard. Kwan feared that O’Hara could stand in the way of inheriting his mother’s home in Newcastle after her death.In January 2024, wearing a disguise and speaking in a fake accent, Kwan injected O’Hara with the highly toxic fumigant pesticide iodomethane, causing pain that Kwan …
Credit: Mohammed Haneefa Nizamudeen / iStock / Getty Images Plus When Aaron Phillips, PhD, was in graduate school, a lab member who became a close friend had a spinal cord injury (SCI). “He shared with me the serious blood pressure instability he faced every day,” Phillips told Inside Precision Medicine. “His experience sparked my curiosity and motivated me to develop and utilize my skills to understand and solve this problem.” Blood pressure instability is a hidden but debilitating consequence of SCI, causing daily dizziness, blurred vision, fatigue, and fainting episodes triggered by standing, eating, or even light exertion. These hypotensive…
The new study compared the bioavailability of Lipo CoQ-10 from Specnova using its LipoVantage technology against placebo and standard CoQ10. “The liposomal formulation of CoQ-10 had a 31.3% higher Cmax and a 22.6% higher AUC0-24 over 24 h compared with the standard formulation (p < 0.001), indicating a remarkable improvement in absorption efficiency,” wrote researchers from Increnovo LLC (USA), Radiant Research Services Pvt. Ltd. (India), Atatürk University (Türkiye), Specnova LLC (USA), Medstar Specialty Hospital (India), and Texas Tech University (USA) in Frontiers in Nutrition. “These results are consistent with previous research showing that liposomal encapsulation improves the bioavailability of nutrients by increasing solubility,…
I never realized just how often plastic comes up in the kitchen—it’s pretty much everywhere. Unfortunately, I believe it’s unavoidable, and I’ve come to terms with that. While it may be difficult to completely remove plastic from my kitchen or food storage, I am all for figuring out how to reduce microplastics wherever I can. Luckily, I found six replacements that are both easy to swap and inexpensive. All of these kitchen swaps are under $20, with some even starting as low as $7. Swap Plastic Utensils for Wooden Utensils OXO Good Grips Wooden Corner Spoon Amazon I love cooking…