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From his spot in the long, orderly queue, Balch could just see the clinic’s large double doors. One intermittently swung open as nurses and national guardsmen ushered the next person inside. The queue then inched forwards like a great lazy caterpillar to fill the vacated space.Balch kneaded his pockets. His turn would be a while yet.Identical clinics had opened worldwide following the parasite’s discovery — a biological oddity colloquially dubbed ‘the Slug’, despite news broadcasts highlighting the microscopic creature’s dendritic shape. How they’d spotted the Slug, Balch couldn’t explain. But he understood why it mattered.Apparently, the Slug had been randomly…
Recent studies highlight a concerning rise in infant gut imbalance, marked by reduced microbial diversity, especially of beneficial bacteria like Bifidobacterium infantis, and increased gut inflammation.With infant gut health moving into the nutrition spotlight, Lallemand Health Solutions and dsm-firmenich say much remains to be discovered. The joint webinar is entitled “Pioneering Partnership: How dsm-firmenich & Lallemand unlock infant microbiome via synbiotics.” Company experts will share the latest research on infant gut health, exploring dysbiosis in early life and the potential of targeted nutritional strategies to support a balanced microbiota. Ahead of the webinar, Nutrition Insight speaks with Valentine Barassé, product manager…
As therapeutic antibodies evolve, the industry is moving away from a one-size-fits-all chromatography approach. With an increasing share of non-traditional monoclonal antibodies (mAbs)—including fragments and multispecifics—entering clinical and commercial phases, manufacturers face new challenges in purification. “Today’s therapeutic-antibody landscape is diversifying,” said Niklas Jungnelius, process modeling leader at Cytiva, during his talk at the BioProcess International Conference in Boston. “These molecules often require other or additional affinities compared to what standard protein A resins can offer and therefore drive demand for a diverse mAb affinity-resin toolbox.” Even traditional mAbs may require adjustments depending on processing conditions, such as pH sensitivity. The shift…
Company advances candidate targeting senescent cells into US study with potential applications beyond dermatology. Rubedo Life Sciences has announced that the US Food and Drug Administration has cleared its Investigational New Drug application for RLS-1496, a selective modulator of glutathione peroxidase 4 (GPX4). The company will now move into a Phase 1b/2a trial in patients with actinic keratosis, beginning in the fourth quarter of 2025. This follows the start of a European trial earlier this year, in which RLS-1496 is being tested in plaque psoriasis, atopic dermatitis and photoaged skin, with results expected around the same time. The new clearance…
A new study suggests 44% of people with diabetes don’t know they have diabetes.The data found that people in sub-Saharan Africa were especially less likely to know their diabetes status.Stay on top of your diabetes risk with physical activity, healthy eating and health care check-ups. In 2023, an estimated 561 million people were living with diabetes, most of whom had type 2 diabetes. Managing diabetes is a lifelong process that can help reduce the risk of serious complications like kidney disease, vision loss and even amputations. The process often involves making lifestyle changes, taking medications to control blood sugar and…
FUJIFILM Biosciences, a global leader in the innovation and manufacture of cell culture solutions for the Life Science market, today announced the commercial launch of BalanCD HEK293 Perfusion A. Designed to expand and augment the company’s portfolio of gene therapy application solutions, BalanCD HEK293 Perfusion A uses suspension HEK293 cells and perfusion technology to provide reliable, efficient, and scalable production of viral vectors for development of gene therapies.HEK293 cells are well established for gene therapy applications in upstream bioprocessing, offering reliable growth rates, high transfection success and expression of cellular factors needed for virus replication. BalanCD HEK293 Perfusion A further…
Tony Delamothe, retired deputy editor, The BMJLondonDavid Isaacs was considered the father of paediatric infectious diseases in Australia and New Zealand12 but he is probably best known in his adopted country for speaking out about the detention of children in Australia’s offshore refugee camps.Isaacs had already set up the Health Assessment for Refugee Kids (HARK) clinic with colleagues in 2005 in response to the needs of refugee children arriving in the country when the Australian government began cracking down on asylum seekers who arrived by boat. They were sent for “offshore processing” on remote islands, including Nauru, a tiny country…
Credit: andresr / Getty Images Screening non-smokers for lung cancer could be a step closer following the results of the Female Asian Nonsmoker Screening Study (FANSS), which highlight the potential value of low dose computed tomography (LDCT) screening in a high-risk population.Lung cancer in individuals who have never smoked (LCINS) is growing in global incidence and is now the fifth most common cause of cancer-related deaths worldwide. Yet, most cases are diagnosed at advanced or late stages as there are currently no screening guidelines for this population. At present, lung cancer screening in the United States via LDCT chest scans…
Just 10 minutes is all it takes to make one of these highly-rated lunch recipes. Receiving 4- and 5-star ratings, these quick and easy meals are standouts among readers, so we’re confident you’ll love them too. From our refreshing Cucumber Sandwich to our hearty Black Bean–Quinoa Bowl, there’s a delicious lunch option here for everyone. Love any of these recipes? Join MyRecipes to save, search and organize your EatingWell recipes all in one place. It’s free! Cucumber-Hummus Wrap Photographer: Ali Redmond. This cucumber-hummus wrap is a crisp, refreshing lunch packed with veggies. Shredded green cabbage adds a satisfying crunch, while the creamy…
Nature, Published online: 17 September 2025; doi:10.1038/d41586-025-02820-3Repetitive head impacts trigger neuronal loss and disrupt blood vessels and immune cells long before the accumulation of neurotoxic tau protein.