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Large, specialized cells in the stomach can quickly reprogram themselves to be small and proliferative by “throwing up,” rather than digesting, unwanted materials.Image credit:©iStock, calvindexterWhen the stomach gets injured, the large, enzyme-secreting cells in its lining, called chief cells, can quickly reprogram themselves to become small, proliferative cells to repair the damaged tissue. Scientists once thought that this dramatic downsizing involved the destruction of the cells’ components through lysosomes, organelles that act as cells’ garbage cans.Jeffrey Brown is a gastroenterologist at Washington University. He studies cellular processes that can turn normal tissue in the foregut cancerous.Jeffrey BrownBut recently, a group…
Factor makes it easy to eat nutrient-dense, protein-packed meals when your schedule’s packed and your fridge is empty. The meals are fresh, flavorful, and way more affordable than takeout, but flexitarians may wish for more high-protein, plant-based options. If you’re craving convenience without sacrificing quality, Factor’s worth adding to your routine. Plus, new customers can save $130 on their first box right now.
During workouts, your muscles use and produce energy through a series of aerobic and anaerobic processes. When oxygen flows constantly through the working muscles, waste byproducts formed as part of muscle metabolism are removed efficiently. However, when oxygen is limited, the byproducts accumulate. Lactic acid is one such product, and it contributes to the “burn” felt during intense workouts. Lactic acid occurs as part of the overall muscle energy output, but too much creates a highly acidic environment. Safe exercise habits and diet can act as lactic acid buffers in the muscles. Read more: Muscle Fatigue & Soreness from Lactic…
Manipulation of DNA. Concept of advancing technology. Adjusting the nut on the screw. [ktsimage/ iStock/ Getty Images Plus] Adding the DNA-repair–targeting drug niraparib to standard hormone therapy early in treatment may significantly delay disease progression for men with metastatic castration-sensitive prostate cancer (mCSPC) carrying homologous recombination repair (HRR) gene alterations, according to new results published in Nature Medicine from the Phase III AMPLITUDE trial. New strategy for an old challenge For decades, the mainstay treatment for mCSPC has been androgen deprivation therapy (ADT)—cutting off the hormones that fuel tumor growth. But while many patients initially respond, relapse is nearly inevitable.…
Hint: It’s a crowd favorite.
This dressing contains gut-friendly ingredients thanks to probiotic-rich strained (Greek-style) yogurt, lemon and honey.It’s quick to prepare and adds perfect flavor to salads, plus it can be used as a dip for veggies.Dressings containing fat help your body absorb vitamins and minerals from the vegetables more effectively. When I was growing up in Iowa, if I was eating salad, it was primarily as a vehicle for bottled dressing. Preferably ranch. I didn’t have a strong preference about what else was in said salad; as long as that creamy, herby dressing was invited to the party, I’d be there. However, now I…
Key takeaways According to Mintel, beauty products will evolve into diagnostic tools, reflecting inner health and merging with wellness tech.Emotional wellness will drive sensory-first product design, with immersive experiences becoming central to beauty routines.Consumers will favour authenticity over perfection, embracing flawed, expressive, and emotionally rich beauty narratives.The market intelligence firm Mintel has today unveiled its annual global beauty trends report, and according to the business, consumers in the coming years will expect serums and supplements to double as wellness diagnostics. Simultaneously, the beauty experience will evolve from delivering visible results to regulating mood and evoking emotion, while imperfection will become…
Nuovo Pasta Pumpkin & Bats Ravioli is back at Costco, featuring festive pumpkin and bat shapes.The rich filling blends mozzarella, Asiago, Parmesan and ricotta for a creamy, comforting flavor.Be sure to stock up each fall to enjoy the ravioli for Halloween and beyond. I’m an avid Costco shopper. I make the 40-minute round-trip visit at least twice a month for lots of things (it’s the best place to buy frozen fruit and cheese, in my opinion). But I also love surveying the aisles for great seasonal items. And one of my favorites is finally back in stock—Nuovo Pasta Pumpkin &…
Representing de Bruijn graphsAccording to the formal definition of a de Bruijn graph, every pair of k-mers (short contiguous subsequences of length k) with an overlap of k − 1 characters are connected with a directed edge. It can be seen that in the de Bruijn graph, the edges can always be derived from the nodes alone, and hence, it is sufficient to store only the k-mer set. These k-mers are used as elementary indexing tokens in MetaGraph.MetaGraph provides several data structures for storing k-mer sets, which are used as a basis to implement different representations of the de Bruijn graph abstraction.…
Amid disputes over pay and training places, the narrative of an exodus of UK doctors has taken hold—but do the data back this up? Elisabeth Mahase investigatesYears of industrial action1 and numerous surveys23 have shown widespread dissatisfaction among doctors in the UK, with concerns spanning pay, working conditions, and access to and quality of training.4The BMA has warned that this “toxic cocktail” is making emigration an attractive option to doctors, and a General Medical Council (GMC) survey over the summer suggested that a third of doctors were looking to leave the UK medical profession.5But while the number of UK doctors…