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Tagomics Ltd., a pioneering biomarker discovery and diagnostics company, today announced the publication of a peer-reviewed study in Cell Reports Methods, underpinning its epigenomic profiling technology, Active-Seq, the basis of Tagomics’ ActivaceTM platform. The paper, titled ‘Genome-wide profiling of unmodified DNA using methyltransferase-directed tagging and enrichment’, built on research from the University of Birmingham, describes Tagomics’ enzymatic approach to epigenomic profiling that targets unmethylated DNA for enrichment, and its application to biomarker identification and disease profiling in colorectal cancer patients. Current gold standard approaches for assessing genome-wide DNA methylation levels are poorly suited to the challenge of working in liquid…

You’ll only need one pot for dinner tonight. These vegetarian recipes combine lots of delicious foods like leafy greens, veggies, legumes and whole grains into one-pot dishes anyone is sure to enjoy. Plus, anti-inflammatory ingredients like carrots, chard and lentils can help you combat pesky symptoms of chronic inflammation like joint pain, muscle aches and mental fog. Try veggie-packed dinners like our Marry Me White Bean Soup and our High-Fiber Butternut Squash & Black Bean Enchilada Skillet for a meal that can help you feel your best. Love any of these recipes? Join MyRecipes to save, search and organize your…

The WHO reveals that food taxes are an evidence-based and effective way to promote healthy diets. The new policy brief argues that current food taxes are too narrow, often targeting just one nutrient like sugar. Since sugar is only a small part of food prices, companies can change recipes, or people can swap products to avoid taxes, which weakens their impact. The WHO advocates a holistic approach to food taxes, using the nutrient profile model (NPM). This would also enable synergies and enhance policy impacts altogether.“Modelling studies have shown that NPM-based food taxes can be more effective in curbing excess…

Cooking for two? These healthy recipes are ready in 30 minutes or less, so you’ll have a perfectly-portioned dinner on the table in half an hour. Even if you’re doing dinner solo, these dishes are a great option to make when you want leftovers to bring to work or school the next day. Recipes like our high-protein Balsamic Chicken Thighs with Arugula-Tomato Salad or our 5-star Sweet Potato & Black Bean Chili for Two are healthy and delicious dinners that won’t take up space in your fridge. Love any of these recipes? Join MyRecipes to save, search and organize your…

Juan VA Franco, family physician1, Timothy J Wilt, professor of internal medicine and public health2, Philipp Dahm, professor of urology31Institute of General Practice, Centre for Health and Society, Medical Faculty, Heinrich Heine University Düsseldorf, Düsseldorf, Germany2Minneapolis VA Center for Care Delivery and Outcomes Research, Section of General Medicine and the University of Minnesota Schools of Medicine and Public Health, MN, USA3Minneapolis VA Healthcare System, Section of Urology and the University of Minnesota Schools of Medicine, Department of Urology, MN, USACorrespondence to: J V A Franco juan.franco{at}med.uni-duesseldorf.dePractice does not reflect evidence or guidelinesTesting for prostate specific antigen (PSA) remains controversial, as…

Sample collectionTwo epithelial brushes (2–3 cm2) from the bladder top (dome) and the bladder floor (trigone) were obtained from 53 people without known bladder pathology and no history of bladder cancer upon autopsy (average 4 days post-mortem) at the University of Washington. Next of kin consented to autopsies and research on leftover specimens. The study of de-identified collected specimens and linked clinical history from the deceased donors was reviewed and deemed not human subjects research by the University of Washington Institutional Review Board (STUDY00016707; IRB Federal Wide Assurance number, FWA 00006878). We obtained the following relevant clinical information for all donors: age,…

Ludlow, A. D., Boyd, M. M., Ye, J., Peik, E. & Schmidt, P. O. Optical atomic clocks. Rev. Mod. Phys. 87, 637–701 (2015).Article  ADS  CAS  Google Scholar  Ushijima, I., Takamoto, M., Das, M., Ohkubo, T. & Katori, H. Cryogenic optical lattice clocks. Nat. Photon. 9, 185–189 (2015).Article  ADS  CAS  Google Scholar  Oelker, E. et al. Demonstration of 4.8 × 10−17 stability at 1 s for two independent optical clocks. Nat. Photon. 13, 714–719 (2019).Article  ADS  CAS  Google Scholar  Schioppo, M. et al. Ultrastable optical clock with two cold-atom ensembles. Nat. Photon. 11, 48–52 (2017).Article  ADS  CAS  Google Scholar  Li, J. et al. A…

Credit: FG Trade/Getty Images The first large-scale study to look at gene expression in brain tissue from African American donors diagnosed with Alzheimer’s disease has identified key differences and similarities between genetic drivers of diseases among Black and White patients. Published today in the Alzheimer’s & Dementia journal, results from the study could help scientists design treatments for this neurodegenerative disease that are effective across people of all ancestries.  In the U.S., the prevalence of Alzheimer’s is approximately two times higher among African Americans than among people with European ancestry. This difference is partly due to reduced access to healthcare…

Besides hearing about some of the latest omics research from both academia and industry, the annual meeting of the American Society of Human Genetics (ASHG) is also the perfect opportunity to learn about some of the latest technologies and partnerships. And this year’s meeting is no exception.  In the lead up to the convening, which will run from October 14-18 in Boston, MA, SPT Labtech, a developer of laboratory automation and liquid handling solutions, and Agilent, a developer of analytical and clinical laboratory technologies, announced the availability of automated target enrichment protocols on SPT Labtech’s firefly®+ platform.  These protocols support…

There is a lot of confusing and conflicting information regarding alcohol and health. This study suggests that any amount of regular alcohol use increases the risk of dementia.If you feel you can’t cope without alcohol, seek help from a health professional. Though we’ve previously reported about alcohol’s potential health benefits, like improving mood or supporting heart health, more and more research suggests that drinking alcohol has far more negative consequences than benefits.  In fact, evidence has surfaced questioning some of these previous findings and alcohol’s supposed benefits. For example, in January 2025, the U.S. Surgeon General issued an urgent warning about…