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When Swedish inventor Alfred Nobel created his prize, which has been bestowed since 1901, he knew no human could run faster than a lion or swim farther than a dolphin. Our dominance as a species arose not because we were the strongest or the fastest, but because of our ingenuity — our ability to imagine, design and build.Are groundbreaking science discoveries becoming harder to find?Today, human ingenuity is expressed through the machines we create. Almost every big scientific breakthrough of the past 50 years, from detecting gravitational waves to sequencing the human genome and mapping the structure of proteins with…

Up & Comers Illumina Illumina may be the longtime leader in next-generation sequencing, but it isn’t quite as established in the spatial field. That’s something the company expects to address next year, when it plans to commercially release a spatial transcriptomics technology it unveiled in February at the 2025 Advances in Genome Biology and Technology (AGBT) General Meeting. Compatible with Illumina’s NextSeq and NovaSeq sequenc- ers and using a new multimodal analysis platform, the company’s spatial technology is designed to let researchers examine the spatial proximity of millions of cells per experiment, using what Illumina says is a capture area…

Garner’s go-to enchiladas use poached chicken, canned soup, and lots of Monterey Jack.The mild, creamy casserole freezes well and feeds a crowd—perfect for sharing.Jennifer’s mom encourages tailoring spice and richness to your personal taste. You might know Jennifer Garner from her performances in 13 Going on 30 or Alias—or you might know her as the sometimes-host of “Pretend Cooking Show” on social media. Garner recently shared another episode of her casual, at-home cooking adventures on Instagram, and this time, it’s a family affair. While on vacation in Nantucket, Massachusetts, Garner and her mom got together to make some nontraditional but…

We’ve pulled together some easy weight-loss meals to make getting dinner on the table a breeze on those busy nights. These are no-fuss recipes that take just 30 minutes or less to prepare. Plus, each dish has fewer than 575 calories and at least 6 grams of fiber and/or 15 grams of protein per serving, so you can meet your weight loss nutrition goals and still have a flavorful, filling meal tonight. Recipes like our Marry Me White Bean Soup or our Broccoli-Cheddar Butter Beans are highly-rated recipes you’ll return to again and again. Love any of these recipes? Join MyRecipes to…

Whole-genome sequencing (WGS) has revolutionized the field of genomics, enabling scientists to explore the complete genetic makeup of individuals with unprecedented detail. By providing a comprehensive view of the genome, WGS has become a critical tool in research, disease diagnosis, and personalized medicine. However, the accuracy of WGS depends not only on the sequencing technology itself but also on library quality. Greg Endress Vice President of Innovations CovarisIn this Innovation Spotlight, Greg Endress, vice president of innovations at Covaris, explains how emerging tools and methods help researchers improve library preparation and achieve more accurate sequencing results. How are scientists currently…

The “What you need to know” box of this Practice Pointer by Rebecca Burch and Eve Rittenberg (BMJ 2025;390:e085564, doi:10.1136/bmj-2025-085564) originally stated that ditans were serotonin receptor antagonists. The online article has now been corrected to say that ditans are serotonin receptor agonists.

What Are Affirmations?Affirmations, also called positive affirmations, are phrases that, when repeated regularly, can change negative thoughts and behavior patterns.[1]They can be said aloud or to yourself. These statements are usually intended to help shift thinking from negative to positive, motivate an action, reduce stress, persevere through difficult times, and increase self-confidence and well-being.“Affirmations help build and improve your self-esteem. They can also act as a way of challenging and replacing your negative and anxious thinking when it comes to stress, depression, physical pain, and anxiety,” says Lee Phillips, LCSW, EdD, a psychotherapist and sex and couples therapist certified by…

Credit: Kateryna Kon/Science Photo Library/Getty Images Research and development teams across academia and industry have been awarded millions of dollars by a U.S. federal agency specializing in health innovation to create at-home screening kits for cancer. The Advanced Research Projects Agency for Health (ARPAH) is funding the development of broadly accessible kits that can detect more than 30 cancers at their earliest stages, when the chances of survival are best. ARPAH’s Platform Optimizing SynBio for Early Intervention and Detection in Oncology (POSEIDON) aims to fundamentally change cancer screening by developing first-in-class, over the counter Multi-Cancer Early Detection (MCED) tests. The…

Vaccine selectively targets toxic forms of amyloid-beta that impair synaptic function and contribute to cognitive decline. Swedish biotech Alzinova has received Fast Track designation from the US FDA for its vaccine targeting Alzheimer’s disease. The news comes hot on the heels of the company securing FDA approval of its Investigational New Drug (IND) application, allowing it to proceed with a Phase 2 clinical trial in the United States. The vaccine, called ALZ-101, is designed to stimulate the immune system to produce antibodies that selectively target toxic amyloid-beta oligomers – soluble, prefibrillar forms of amyloid-beta that are believed to play a…

CEFI (from the French, Comité Européen des Fabricants d’Inuline) consists of Beneo, Cosucra, and Sensus and is a non-profit organization representing the world’s major chicory inulin producers. The association cooperates on regulatory topics related to health, nutrition, and sustainability in the EU and beyond. The International Probiotics Association, founded in 1999, expanded its scope in 2023 to include prebiotics, postbiotics, and synbiotics, and this has been followed by publications and position statements over the past couple of years. Earlier this year, IPA adopted the ISAPP definition of prebiotics, in a move that the association described as signifying “IPA’s commitment to…