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Proteins are most well-known for their intricate structures. The α-helices and β-sheets that form from interactions between sidechains create distinct shapes that, along with the specific amino acid sequences themselves, allow these molecules to perform unique functions in cells. “Most proteins use all 20 amino acids—alanine, valine, methionine—they use all of them. So it’s like a card deck,” said Steven McKnight a molecular biologist at the University of Texas Southwestern Medical Center. Incorporating all or most of these amino acids creates complexity in the polypeptide chain that allows proteins to fold into their unique structuresHowever, some proteins contain regions, called…

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Gene Feder, professor1, Elizabeth A Cook, senior lecturer2, Sally McManus, professor21Centre for Academic Primary Care, Department of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK2Violence and Society Centre, University of London, London, UKgene.feder{at}bristol.ac.ukThe Terminally Ill Adults (End of Life) Bill is approaching its second reading in the UK House of Lords. If passed, it will allow people who are terminally ill and expected to die within six months to request assistance to end their lives.1 We believe that the safeguards in the bill need to be strengthened to prevent coercion in the context of domestic abuse.Despite requests…

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Even if you’ve never had a severe allergic reaction, that doesn’t mean you’ll never need to worry about anaphylaxis or anaphylactic shock. “People can develop severe, life-threatening allergies at any age,” says Randhawa. “Adult-onset food allergies, for example, are becoming more recognized, and reactions can be just as serious as those that start in childhood.”Similarly, just because allergic reactions have been mild for you in the past doesn’t mean they’ll continue to be. “Some people have unpredictable reactions — mild one time, severe the next,” says Randhawa. “However, once you’ve had a severe reaction, you’re at higher risk for future…

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This side dish is simple enough for a weeknight dinner, but also impressive for a holiday meal.Butternut squash provides fiber and potassium to support heart health. The maple butter is so delicious, you’ll want to pair it with other vegetables. This Melting Butternut Squash with Maple Butter lives up to its name—caramelized on the outside, buttery-soft on the inside and rich with warm, sweet flavors. The real magic lies in the “melting” technique: after the squash is roasted at high heat to build color and flavor, it’s finished with a splash of broth in the baking dish. This final step allows…

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Experts discussed these challenges as well as opportunities for change in a meeting ahead of the 73rd International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA) held last week in Naples.Ashwagandha top of the agendaDeepak Mundkinajeddu, head of research and development at the Italian sustainable manufacturer Natural Remedies Ltd, explained how global warming is a problem for both water- and heat-loving botanicals, specifically ashwagandha and bacopa.“The two plants have a contrasting need in agroclimatic conditions for growth,” he said. “Ashwagandha thrives in semi-arid to dry subtropical regions of India, while bacopa is a…

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Seeing as though September is my birthday month, I think it’s time to treat myself to some new workout gear. I have a few pairs of great walking sneakers, but I’ve been rotating through the same two shirts and pants for my workouts. I exercise at least four times a week, so I’ve been doing load after load of laundry just to have clean leggings for my next walk. Now is a great time to finally refresh my wardrobe with pieces from Lululemon’s “We Made Too Much” section, an overstock page that includes the brand’s most popular lines for less. …

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