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Credit: Steinack & Gaisl / ERS A cutting-edge bronchoscopy technique, guided by a robotic arm and a specialized cone-beam CT (CBCT) scanner, outperforms traditional diagnostic methods when it comes to small, hard-to-reach tumors found in the periphery of the lungs. These findings from an ongoing clinical trial at University Hospital Zürich were presented on Sunday at the European Respiratory Society (ERS) Congress. “Robotic-assisted bronchoscopy with CBCT achieved a diagnostic yield more than three times higher than conventional bronchoscopy,” said Carolin Steinack, MD, senior physician and head of the Interventional Lung Center at University Hospital Zürich. “In clinical practice, this technology…

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For large language models (LLMs) like ChatGPT, accuracy often means complexity. To be able to make good predictions, ChatGPT must deeply understand the concepts and features that are associated with each word—but how it gets to this point is typically a black box. Similarly, protein language models (PLMs), which are LLMs used by protein scientists, are dense with information. Scientists often have a hard time understanding how these models solve problems, and as a result, they struggle to judge the reliability of the models’ predictions. Bonnie Berger is a mathematician and computer scientist at the Massachusetts Institute of Technology. She’s…

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Differences in biology may make weight loss easier for men than women.Men tend to have more muscle mass and higher testosterone levels, plus faster metabolisms.Women’s monthly hormonal shifts may increase appetite and cravings and promote fat storage. If you’re a woman who’s ever tried to lose weight alongside your male partner, then you’ve probably had the all too common experience of watching him drop five to 10 pounds in the first few weeks. Meanwhile, you’ve gained three pounds. The frustration is real. But it’s not your imagination. Science has found that it may actually be easier for men to lose…

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The Ministry of Food and Drug Safety (MFDS) said on Tuesday (Sep 23) that the warning “in rare cases, it may cause harm to the liver, and alcohol consumption should be avoided during intake” will be added to Garcinia cambogia products. This is the second time that MFDS has implemented controls on Garcinia cambogia products in this year alone. Since January, the regulator has stopped companies from formulating Garcinia cambogia extract with other ingredients that similarly have body fat reduction functions. The recommended daily intake of Garcinia cambogia extract was also reduced from 750-2,800 mg/day to 750-1,500 mg/day. The MFDS…

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“Define what wellness means to you. Prioritize activities that make you feel better, not activities you think you should be doing because an influencer told you to. It could be as simple as going for a walk, sitting in a park, and getting 15 minutes of sun. Wellness routines don’t have to be elaborate and expensive. The simpler they are, the more likely you are to do them,” says Elaine Proulx, a health and wellness coach and owner of ESP Wellness.

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DataTable 1 summarises the characteristics of the training data. Of the 480 651 individuals included, 7168 (1.5%) had MALO diagnosed during follow-up. The median follow-up was 27.7 (interquartile range 22.6-32.2) years, corresponding to 12.3 million person years of follow-up. Figure 1 describes the observed MALO events in the training data. A total of 7168 MALO events occurred during follow-up, of which 1331 (19%) occurred during the first 10 years, giving a cumulative incidence at 10 years of 0.27% (95% confidence interval 0.26% to 0.29%).Fig 1 Graphical summary of major adverse liver outcomes (MALO) in training data. Top: histogram of distribution of…

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Oceans churned with lava. Air filled thick with smoke. Asteroids stormed down incessantly. Life during the Hadean Eon four billion years ago was a struggle, and yet that was when it began.1,2 With no fossil record dating this far back, biochemists ruminating over life’s inception have tried to reconstruct its origin story in the laboratory. While so much remains unknowable about life’s deep history, most trust that it kicked off with a timeless polymer—one that organisms continue to use today: ribonucleic acid (RNA).3Cells of the modern world are seemingly too complex to have appeared spontaneously. “You use nucleic acids to…

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Trader Joe’s Chicken Burrito Bowl is a top fiber-packed pick by dietitians.It has 9 grams of fiber and 22 grams of high-quality protein, making it filling and nutritious.When choosing frozen meals, pick ones high in fiber, plants and lean proteins. If “frozen TV dinner” makes you think of unhealthy, compartmentalized packages of food, it’s time to update that image. Nowadays, many frozen dinners are made with whole-food ingredients packed with nutrition—making it feasible to eat healthy on busy nights. Frozen meals with plenty of fiber are especially valuable, as most Americans fall short of the recommended 25 to 38 grams…

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