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Credit: LSOphoto/Getty Images Men and women with severe asthma (SA) have innate differences in immune cells along their airways that could impact on treatment with biologics, a study has shown. The findings, Science Translational Medicine, highlight the impact of not taking sex into account in studies, the researchers say. Deep phenotyping revealed sex differences in precursors to different types of innate lymphoid cells (ILCs) at mucosal surfaces, such as the mouth and airways. “This study emphasizes the need to recognize the phenotypic heterogeneity of ILCs in a clinical setting and highlights that examination of clinical cohorts at a population level,…
The ocean is a reservoir of nutrients; however, not everyone has equitable access to them. The World Trade Organization (WTO) recently reached an agreement on Fisheries Subsidies to prevent fish depletion and protect fishing communities’ livelihoods. By cutting subsidies, the landmark move curbs government support for illegal fishing and the exploitation of stocks and protects marine life. Nutrition Insight speaks to an expert to explore how the deal could influence the nutrition industry and food security — particularly as fish remains a key component of many healthy diets.Nicole Franz, research scholar at the Center for Ocean Solutions at Stanford University, US,…
Ina Garten’s Chicken in a Pot with Orzo is a perfect meal for fall.It includes whole chicken, veggies like carrots and leeks, orzo pasta and fresh herbs.Pair this meal with a refreshing salad for a complete dinner that serves four. Cooking a delicious, fragrant dinner can be a soothing activity, but doing the dishes can be a real pain. That’s where the appeal of the one-pot dinner, whether it’s a delicious vegetable soup or creamy pasta dish, comes into play—and it’s no surprise that Ina Garten has added a tasty recipe to the one-pot genre. Getty Images We love Ina’s…
Susan Monarez was fired from her role as director of the US Centers for Disease Control and Prevention after refusing to strip staff members of their jobs.Credit: Alyssa Schukar for NatureWhen Susan Monarez took the helm of the beleaguered US Centers for Disease Control and Prevention (CDC) in late July, she had her work cut out for her. Public trust in the agency had dropped considerably since the start of the COVID-19 pandemic. And US health secretary Robert F. Kennedy Jr, who oversees the CDC, had called the agency a “cesspool of corruption” that needed to be fundamentally rebuilt.Less than…
Longevity biotech seeks to broaden its therapeutic capabilities with cellular reprogramming and delivery technologies. Longevity-focused biotech Klotho Neurosciences revealed it has issued a Letter of Intent to acquire “select assets” from Turn Biotechnologies, a biotech specializing in cellular reprogramming and mRNA-based therapies. While the announcement disclosed that Klotho would gain access to Turn’s epigenetic reprogramming platform and RNA delivery technology, it did not provide clarity on which of Turn’s development programs would be included in the acquisition. To date, Klotho Neuro had largely built its strategy around the klotho gene, first identified for its role in regulating aging and protecting…
Money on your mind, Pisces? As this Aries full moon moves through your second house of money, possessions, and financial security, this is a great opportunity for you to focus on and prioritize your finances. If you’ve been spending frivolously, or in ways that aren’t in your best interest, for example, you’re being asked to shape up.
Anocca senior bioengineer Jonas Frey analyses data from an automated liquid-handling robot in one of the company’s research and development laboratories.Credit: AnoccaThe meaning behind our monikerAnocca, a biotechnology firm in Södertälje, Sweden, develops precision T-cell immunotherapies to recognize cancer targets. It was co-founded by New Zealander Reagan Jarvis, a physician and biochemist who is now the company’s chief executive, and Mikael Blomqvist, a Swedish entrepreneur who sits on the board of directors. Jarvis describes how they chose a name that, to them, felt memorable and distinctive, but “not too sciencey”. This is the fourth article in a six-part series about…
Researchers at the La Jolla Institute for Immunology (LJI) and Columbia University Irving Medical Center have uncovered evidence that amyotrophic lateral sclerosis (ALS) may be an autoimmune disease. The team discovered that inflammatory immune cells, called CD4+ T cells, mistakenly target certain proteins that are part of the nervous system in people with ALS. “This is the first study to clearly demonstrate that in people with ALS, there is an autoimmune reaction that targets specific proteins associated with the disease,” says LJI Professor Alessandro Sette, PhD, who co-led the study with Professor David Sulzer, PhD, of the Columbia University Irving…
Michael Chen, PhD Cofounder and Chief Executive Officer NucleraFor Michael Chen, the path from academia to biotech entrepreneurship began with a protein that refused to cooperate. His laboratory struggles, coupled with those of his fellow classmates, became the spark for Nuclera, the biotechnology company that they founded to make proteins more accessible for better research and drug discovery. Today, Chen serves as the transatlantic company’s chief executive officer, leading a team focused on the eProtein Discovery™ platform, designed to streamline protein synthesis and characterization.What makes Nuclera unique?Proteins are comprised of 20 or more amino acids, and each amino acid sequence…
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