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Relish trays have graduated from Grandma’s go-to appetizer to a modern crowd-pleaser.  Unlike charcuterie boards, which spotlight cured meats, relish trays lean into crisp produce for a lighter spread. Think of them as a no-cook canvas: bright pickles, raw or blanched veggies, a swipe of creamy dip, plus a few wedges of sharp cheese and whole-grain crackers. Everything can be prepped quickly or ahead of time, then arranged just before guests arrive, so you get maximum flavor with minimal fuss. Whether you’re hosting a game-day gathering or adding color to your holiday buffet, recipes like our Chopped Waldorf Salad Dip…

Fluorescent microscope image of the proximal tubule, the part of the kidney that’s most affected by ceramides. [Luis Cedeño-Rosario] Serious damage to short-term kidney function, known as acute kidney injury (AKI) can be fatal and also increase the risk of irreversible chronic kidney disease. It may be triggered by stressors ranging from sepsis to heart surgery, and affects more than half of ICU patients. Researchers at University of Utah Health (U of U Health) have now reported the results of preclinical in vitro experiments and studies in live mice suggesting that AKI is triggered by fatty molecules called ceramides, which…

Ree Drummond preps nearly every dish ahead to ease stress on Thanksgiving Day.Her holiday menu includes classics like turkey, stuffing and two kinds of pie.Wednesday is the busiest prep day—including casseroles, pies and turkey brining. For those of us hosting Thanksgiving dinner (or any of the events surrounding it), it can be really difficult to come up with a “game plan.” You have to decide not only what dishes you’re making (or assigning out), but how much of everything to make. Unless you have a multi-oven kitchen with infinite burners, you need to come up with an order of operations…

Baxter, S. M. et al. Centers for Mendelian Genomics: a decade of facilitating gene discovery. Genet. Med. 24, 784–797 (2022).CAS  PubMed  PubMed Central  Google Scholar  Taylor, J. C. et al. Factors influencing success of clinical genome sequencing across a broad spectrum of disorders. Nat. Genet. 47, 717–726 (2015).CAS  PubMed  PubMed Central  Google Scholar  Wright, C. F. et al. Genomic diagnosis of rare pediatric disease in the United Kingdom and Ireland. N. Engl. J. Med. 388, 1559–1571 (2023).CAS  PubMed  PubMed Central  Google Scholar  Rimmer, A. et al. Integrating mapping-, assembly- and haplotype-based approaches for calling variants in clinical sequencing applications. Nat.…

Sponsored By: This Inside Precision Medicine podcast explores how advances in DNA methylation research are transforming diabetes care. The discussion with Charlotte Ling covers motivations for focusing on methylation as valuable prognosticator of disease, the advantages of methylation risk scores (MRS) compared to polygenic risk scores (PRS), and novel gene associations linked to cardiovascular complications in diabetes. She articulates the validation needs across diverse populations, the influence of lifestyle on methylation stability, and strategies for translating these biomarkers into clinical tools. Finally, she reflects on evolving technologies, future applications of methylation biomarkers, and the potential.  

This is particularly evident in the growing research surrounding the gut microbiome composition needed to optimize development during the first 1,000 days of life by identifying the missing microbes in modern baby biomes.Beyond the tried-and-trues like calcium and vitamins C and D, the science is also investigating a broader range of bioactives to address digestive health, sleep, mood and behavior, weight management, eye health and allergies, and there is a marked and growing interest in products for cognitive function, focus and memory.Below a round-up of some of the latest science, exploring ingredients from protective biotic strains targeting conditions like child…

A recent study investigated the nutritional consumption of pasteurized dairy products and brownies enriched with flour made from mealworms (Tenebrio molitor). It is the first to offer a tasting of these products in the Mediterranean region to determine how well they are accepted in this cultural and culinary setting. The research team highlights “very positive” results, particularly for the brownies. Mealworm hydrolysate improved their texture, making them softer and more elastic.“This shows that, with the right formulation, products with insect protein can be attractive to consumers and have a place in our cuisine,” say the researchers.In addition to significantly improving…

Breitbart, M., Thompson, L. R., Suttle, C. A. & Sullivan, M. B. Exploring the vast diversity of marine viruses. Oceanography 20, 135–139 (2007).Article  Google Scholar  Gao, E.-B., Huang, Y. & Ning, D. Metabolic genes within cyanophage genomes: implications for diversity and evolution. Genes 7, 80 (2016).Article  PubMed  PubMed Central  Google Scholar  Puxty, R. J., Millard, A. D., Evans, D. J. & Scanlan, D. J. Shedding new light on viral photosynthesis. Photosynth. Res. 126, 71–97 (2015).Article  CAS  PubMed  Google Scholar  Zimmerman, A. E. et al. Metabolic and biogeochemical consequences of viral infection in aquatic ecosystems. Nat. Rev. Microbiol. 18, 21–34 (2020).Article …

England is facing one of the toughest ever winters in its history as an early wave of flu sweeps the nation, health officials warn.Flu rates have started climbing much sooner than usual this year,1 driven largely by cases in young adults and schoolchildren.2 And experts warn that the H3N2 strain, currently dominant in cases in England, mutated seven times over the summer, making it more severe than normal.Amid growing concern that hospitals will be overwhelmed this winter, health officials have urged all eligible groups, including people over 65, people with certain long term conditions, pregnant women, and children, to get…

The turkey may take centerstage on Thanksgiving but chefs say the real magic is in the gravy.For the best gravy chefs say using the neck and giblets is a must and roasting provides a deep, rich flavor.Chefs share other gravy-making secrets like using a wine, miso, fresh herbs and even tips for thickening. Thanksgiving dinner is all about that juicy, golden brown roasted turkey. But for many households, it’s the one time of time of year they cook an entire bird, so it’s not surprising many struggle to get it right.  A turkey is very easy to overcook. Luckily, a…