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For years, the humble chicken breast reigned supreme in the world of fitness and healthy eating, often leaving the darker, more flavorful cuts in the shadows. However, the tide is turning. There is a rapidly rising interest in chicken thigh nutrition as home cooks, chefs, and nutrition-conscious eaters alike rediscover the superior taste, texture, and affordability of thighs.  While breasts are lean, they can often be dry and flavorless if not cooked perfectly. Thighs, on the other hand, are forgiving, juicy, and packed with essential nutrients that go beyond just protein. But with that extra flavor comes questions about fat…

Peppermint tea is far more than just a festive holiday beverage or a refreshing palate cleanser. For centuries, this aromatic herbal infusion has been revered not only for its cool, crisp flavor but also for its profound medicinal properties.  As modern science begins to validate traditional wisdom, the benefits of peppermint tea are becoming a cornerstone of natural wellness routines worldwide. From soothing a stubborn stomach ache to sharpening mental focus without the jitters of caffeine, this humble herb offers a versatile toolkit for better health. In this comprehensive guide, we will explore the extensive health benefits of peppermint tea,…

Credit: chaikom/Getty Images Researchers in the engineering and computer science department of Florida Atlantic University (FAU) report they have developed a deep learning model that uses electroencephalography (EEG) to differentiate Alzheimer’s disease (AD) and frontotemporal dementia (FTD), two conditions with similar symptoms but which damage different regions of the brain. The study, published in Biomedical Signal Processing and Control, details how the new method reduces signal noise from EEG readings to boost its accuracy by analyzing both frequency- and time-based brain activity patterns specific to each disease. “What makes our study novel is how we used deep learning to extract…

Findings from a new study led by scientists at Stanford University School of Medicine and their colleagues elsewhere show that a single signaling pathway controls whether immune cells attack or befriend cells that they encounter in the body. By manipulating this pathway, scientists may be able to tweak the immune response to treat a range of diseases, including cancers, autoimmune disorders, and more. Full details are provided in a new Nature paper titled “Erythropoietin receptor on cDC1s dictates immune tolerance.”   The findings build on work published in an earlier study by the same research group that described a role for erythropoietin (EPO)…

Credit: SoumenNath / Stock Photos / Getty Images Precision immunotherapy tailored to patients with sepsis can improve their outcomes compared with placebo treatment, according to a trial conducted at 33 intensive care units in six countries. The approach, outlined in JAMA, could help clinicians design targeted interventions in which sepsis patients are treated according to their distinct immune responses. Personalizing immunotherapy according to immune profile was better at reducing dysfunction in the vital organs of these critically ill patients versus placebo in the ImmunoSep trial. Nearly twice as many patients receiving immunotherapy based on biomarkers achieved the primary endpoint threshold…

In 2022, monkeypox virus (mpox) caused more than 150,000 cases—causing flu-like symptoms and painful rashes and lesions. The outbreak resulted in almost 500 deaths. At the time, vaccines developed to fight smallpox were repurposed to help the most vulnerable patients. But that vaccine—manufactured from a whole, weakened virus—is complicated and costly to make. Now, a major inroad towards a new and more effective way to fight monkeypox virus has been published. A team used the AlphaFold 3 model to identify a viral surface protein—OPG153—as a good target for developing new antibody therapies to treat mpox or for use in a…

Credit: Christoph Burgstedt/Getty Images Results from the Phase III lidERA clinical trial show that giredestrant, an adjuvant therapy for early-stage hormone receptor-positive (HR+), HER2-negative breast cancer, significantly reduced the risk of recurrence compared to standard endocrine therapies after surgery. Presented today at the San Antonio Breast Cancer Symposium (SABCS), these findings could mark the first major shift in adjuvant therapy for breast cancer in over 25 years.  “This is perhaps one of the most important breast cancer advances in recent years for hormone receptor-positive disease,” said Aditya Bardia, MD, MPH, professor of medicine at the University of California, Los Angeles…

Scientists from the Netherlands have tested whether a popular analytical technology can be calibrated without needing to go through the expense of running a bioreactor. The team, from Delft University of Technology (TU Delft), found that their technique for calibrating Raman spectroscopy using single compounds, such as glucose, to calibrate a model performed as well or better than data obtained from real processes. According to Marieke Klijn, PhD, an assistant professor at TU Delft, the new research could help researchers to benefit from analytical technology earlier in process development. “Our team noticed that [academic] papers written by companies or collaborators with…

A protein used in red blood cell formation steers dendritic cells to drive regulatory T cell differentiation.Image credit:©iStock.com, Meletios VerrasThe immune system consists of inflammatory and regulatory T cells (Tregs) that promote or dampen immune activity, respectively. These cells react to specific antigens that specialized cells like dendritic cells present to them. Dendritic cells also provide T cells with directions for what subtype of T cell to become: stimulatory or tolerant. “What had yet to be discovered is the mechanism responsible for inducing or activating Tregs in those circumstances when they are needed to suppress a dangerous immune response,” said…

Comparison of human umbilical cord blood with adult plasma revealed hundreds of metabolites whose abundances were age-dependent. Two different formulas, each a mix of a few metabolites, demonstrated anti-senescence properties in cell cultures and model organisms [1]. Young blood has benefits Previous research has provided evidence that surgically connecting the circulatory systems of young and aged mice, known as parabiosis, in which older animals receive blood from young animals, can lead to reversal of age-associated deterioration in the older animal [2]. Going one step further (or rather, one step younger) is to investigate the properties of human umbilical cord blood…