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Credit: blueskies9/Fotolia Only certain healthy, older people could stave off cancer using low-dose aspirin (LDA), according to a secondary analysis of a large clinical trial that flags those who might benefit. Primary results from the trial did not show that 100 mg per day enteric-coated aspirin prevented cancer over the course of five years among its nearly 20,000 participants. But the extended analysis, published in JAMA Oncology, suggests there were benefits for older people and those who were non-smokers, had a family history of cancer, or a lower body mass index. Others who benefited included participants with the age-related phenomenon…

Candida albicans occurs naturally in the human microbiome and usually remains harmless. Under certain conditions, however, it can transform from its yeast form into thread-like hyphae and cause infections that can have fatal consequences, especially in immunocompromised patients. In this hyphal form, C. albicans produces the toxin candidalysin, a protein that directly attacks host cells. Now, new research reveals that C. albicans not only uses the toxin candidalysin to cause infections, but also to colonize the oral mucosa inconspicuously—but only in finely balanced amounts. Too little toxin prevents oral colonization, too much triggers the immune system and leads to an inflammatory…

DNA is the raw material of modern medicine yet is the only part of drug development not accessible at the lab bench. DNA synthesis, the first step in most biological workflows including gene synthesis, PCR primer design, next-generation sequencing (NGS) panel creation, and gene expression studies, is often outsourced. This is largely due to the historical complexity and technical challenges associated with synthesizing DNA. As a result, ordering and delivery delays create bottlenecks that slow down innovation. Xavier Godron, MEng Cofounder and Chief Technology Officer DNA ScriptDNA Script has developed a benchtop enzymatic DNA synthesis (EDS) system that enables rapid,…

They can thank their ruling planet, Mercury, for that, which is the planet of communication and information. Their Mercurial mind makes them especially adept at explaining thoughts, feelings, or concepts in a way that’s actually understandable, and often witty or charming to boot.

Fewer than one in 20 adults with high blood pressure use salt substitutes to cut sodium.Uncontrolled blood pressure can harm your heart, brain and kidneys over time.Salt substitutes are easy to find in stores but remain an underused tool for BP control Salt substitutes may be an easy way to cut back on sodium, but a new study shows that Americans rarely use them. The findings, presented at the American Heart Association’s Hypertension Scientific Sessions, raise questions about why such a simple dietary swap remains uncommon—and whether health professionals should be talking about it more often with patients. Hypertension, or…

As for the taste, well, it’s slightly sweet and salty, yet sort of bland, which makes it easy to add to dishes without altering the flavor. The real hurdle, if you’re not a fan of curdled cheese, is the texture. It’s equally lumpy, bumpy, and creamy, making it quite polarizing. But if the texture doesn’t weird you out, the taste itself can be rather enjoyable.

Unexpected US intervention has led to a declaration to tackle non-communicable diseases (NCDs) failing to be approved at the United Nations.During the fourth high level meeting on NCDs and mental health at the UN General Assembly in New York on 25 September, dozens of statements were read by member state representatives supporting the declaration.1But as the US health and human services secretary Robert F Kennedy spoke he said the US rejected it. He claimed that the UN had exceeded its role, by going, for example, too far in recommending taxes on unhealthy products. He also criticised it for its stance…

Symptoms of Hereditary AngioedemaSwelling is the common theme in all HAE episodes. But different parts of your body may be affected. Your signs and symptoms might depend on the type of attack you have.Subcutaneous AttacksThese attacks affect areas of the skin, usually on the face, hands, feet, or genitals. Your skin will swell and may turn red, but it usually doesn’t itch. Sometimes a skin attack causes temporary disfigurement. The swelling can make it hard to perform simple activities like walking or holding a pen. Subcutaneous attacks are often mistaken for allergic reactions.[1][2]Abdominal AttacksAbdominal attacks involve swelling in the intestinal…

GlycanAge’s Gordan Lauc on individuality, biology’s hidden signatures, and why epigenetic clocks may redefine how we measure aging. The Global Longevity Summit 2025, hosted by A4M, will bring together researchers, clinicians and entrepreneurs in Geneva next month to debate how emerging science can be applied in practice. Central to the agenda are questions of measurement – how we assess biological aging, how we translate these tools into clinics and how individual variation can guide more effective interventions. The meeting also reflects a wider shift in healthcare, as policy makers and practitioners begin to confront the societal and economic challenges of…

You have full access to this article via your institution. Hello Nature readers, would you like to get this Briefing in your inbox free every day? Sign up here.Maria Branyas Morera had been verified as the oldest living person when she died last year at age 117.Credit: Xavier Dengra (Public Domain)A healthy diet and a bit of genetic luck helped Maria Branyas Morera live to the grand old age of 117. Before she died, researchers found that Branyas had genetic variants known to protect against cardiovascular disease, and none that increased risk of deleterious conditions such as Alzheimer’s. Blood tests…