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Cholesterol is the waxy, fat-like substance made by your liver and essential for making hormones and digesting fatty foods.HDL is often called the “good cholesterol” and requires a higher number for better heart health.Health experts say the simple activity to start today to raise your HDL is to increase your cardio.  Cholesterol is the waxy, fat-like substance made by your liver. It is involved in important processes such as making cell membranes and hormones and digesting fatty foods. Too much cholesterol can lead to plaque in your arteries and eventually heart disease or stroke. But not all cholesterol is the…

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This study complied with all relevant local ethical regulations. Approval for the use of ICF patients’ fibroblasts was obtained after informed consent from all patients or their families (for minors), in agreement with the Helsinki Declaration (CNIL authorization—908256; 14 October 2008)41,66.Cell culture and drugsCells were maintained at 37 °C in a humidified incubator at 5% CO2. Cell lines with DOX-inducible constructs were cultured with 10% tetracycline-free FBS (Biowest). DLD-1 cells were cultured in DMEM–GlutaMAX medium (Gibco) supplemented with 10% FBS. hTERT RPE-1 cells were cultured in DMEM/F-12 GlutaMAX medium (Gibco) containing 10% FBS and 0.123% sodium bicarbonate. HCT116 cells were cultured…

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DNA methylation is a key epigenome component that helps dictate how genes are expressed, contributing to normal cell and tissue differentiation during development, as well as the process of biological aging. However, aberrant DNA methylation is involved in many different diseases, including cancer, neurological disorders, and autoimmune disease. In this article, explore what DNA methylation is and how it affects gene expression, techniques for DNA methylation sequencing, and the effect of DNA methylation on human health.DNA methylation controls gene expression without altering the underlying DNA sequence.iStock, agsandrewWhat Is DNA Methylation?DNA methylation is a type of epigenetic DNA modification that affects…

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A nutritious black bean and rice bowl with leftovers and pantry staples is a favorite Friday meal.Preparing the ingredients is quick and easy, allowing dinner to be on the table within 45 minutes.I like adding chopped avocado, onions and a drizzle of lime juice for extra flavor. I love to cook, but sometimes answering the question of what’s for dinner can be stressful—especially during the week, when deadlines and other commitments take priority. And when I’m hungry at the end of the day and don’t have a dinner plan in place, that’s when I’ll raid the fridge for random ingredients…

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Your doctor will recommend fertility preservation options depending on your gender, age, and reason for wanting to preserve your fertility.Egg FreezingSome women choose to freeze their eggs, also called egg cryopreservation, to delay having children or when a disease has damaged their ovaries. Walter says this process is similar to in vitro fertilization (IVF) treatment for infertility. It starts with taking hormone medications that stimulate the ovaries to grow and produce several eggs (this is called ovarian stimulation). Once the eggs have matured, the doctor removes them during an outpatient procedure. The eggs are stored in liquid nitrogen tanks until…

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In one of my favorite parenting books, Hunt Gather Parent, author Michaeleen Doucleff, Ph.D., states, “What if we think of (children) as illogical, newbie citizens trying to figure out the proper behavior? What if we assume their motivations are kind and good, and it’s just that their execution needs some improvement?”

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