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Bella Devaleenal Daniel, scientist1, Chandrasekaran Padmapriyadarsini, director1, Sidhartha Giri, scientist2, Paran Sarimita Winarni, vice chair and TB survivor31ICMR National Institute for Research in Tuberculosis, Chennai, India2ICMR Regional Medical Research Centre, Bhubaneshwar, India3Pejuang Tangguh (PETA), Jakarta, IndonesiaCorrespondence to: BD Daniel belladevalleenal.d{at}icmr.gov.inWhat you need to knowUniversal drug susceptibility testing is key for early diagnosis of drug resistant tuberculosis (TB) and should be offered to all people with bacteriologically confirmed TB; rapid molecular diagnostic tests used as an initial di(eagnostic investigation can simultaneously detect Mycobacterium tuberculosis and drug susceptibility early.Treatment of people with multidrug resistant TB or rifampicin resistant TB with shorter oral…
Changes in the political climate of the United States are spilling into scientific research. While many past administrations, of both parties, supported and funded science funding and education, the current administration has enacted cuts to currently funded research upwards of 40% and the proposed budget for the 2026 fiscal year shows a 39.3% cut to NIH funding. While this may not be initially concerning to most people who may ask how this could possibly impact their daily lives—it is a pressing concern when one considers the broader impacts of reduced research funding. “Recently, when asked to assess how large NIH…
Nature, Published online: 25 September 2025; doi:10.1038/d41586-025-03019-2The chemical make-up of crystals that formed from magma hint at an increase in the number of meteorites battering Earth’s surface.
Credit: bymuratdeniz / iStock / Getty Images Plus Jonathan D. Grinstein, PhD, North American Editor of Inside Precision Medicine, hosts a new series called Behind the Breakthroughs that features the people shaping the future of medicine. With each episode, Jonathan gives listeners access to his guests’ motivational tales and visions for this emerging, game-changing field. Shana Kelley, PhD, is unafraid to tackle ambitious scientific challenges—concepts that might seem drawn from science fiction. For example, she envisions technologies that could monitor immune system activity in patients in real time, much like a glucose monitor tracks blood sugar levels. Transforming such a…
A few years ago, researchers accidentally discovered short peptides that could self-assemble into net-like structures in the presence of bacteria. Now, by tweaking the peptides’ sequence, they could control how well these nets trap and kill bacteria.Image credit:Wei Meng ChenThe World Health Organization estimates that antibiotic resistant infections kill more than a million people worldwide every year, so many researchers are actively looking for new ways to combat it.Rachel Ee (right), a biotechnologist at the National University of Singapore, designs antimicrobial peptides to combat antibiotic resistance. In a recent study led by her graduate student Wei Meng Chen (left), Ee’s…
Gordon Ramsay toasts oats, nuts and seeds to deepen flavor in overnight oats.A sweet, buttery spice mix adds warmth and flavor to every bite.The final texture is creamy and pudding-like, with optional fresh toppings. Overnight oats are one of those breakfasts that can have infinite permutations, so you’d never get bored of your hearty, whole grain breakfast—as long as you’re a fan of creamy oats. If you love a cool bowl (or jar) of oats in the a.m., it’s a great option for breakfast because you can make it ahead and pack plenty of protein and nutrients. And if you’re…
Is soda bad for you? Drinking soda every day could negatively impact your health.Side effects from drinking to much soda include indigestion, jitters, mood swings and a need for sugary foods.Consider sipping on a kombucha, seltzer water or a sparkling tea instead of soda. Soda, like all things, can be enjoyed in moderation. And while it’s pretty common knowledge that soda isn’t the greatest for your health, what really happens to your body when you drink soda? You may have seen various videos online showing how soda can be used to clean pennies, create soda-bottle volcanoes when paired with Mentos…
Bin Peng, attending physician, Songmei Geng, chief physicianDepartment of Dermatology, Xi’an Jiaotong University Second Affiliated Hospital, ChinaCorrespondence to: S Geng gengsongmei73{at}163.comThis woman in her late teens presented to the dermatology department with a one month history of a pea sized nodule on her chin. The lesion was characterised by superficial ulceration, surrounding skin depression (figure), and no associated pain or itching. She reported no history of trauma or medical history, and took …
Researchers at Hospital Santa Maria and other institutions in Portugal conducted a literature search and meta-analysis of 14 clinical trials to evaluate the effects of omega-3 supplementation on cognitive decline. The results revealed modest but consistent improvements, which “are unlikely to be due to chance alone and represent a genuine therapeutic effect,” the researchers wrote. The results also suggested a threshold effect rather than a dose-response relationship. “These findings support n3-PUFA supplementation as a complementary approach to lifestyle-based strategies for cognitive health, including diet, physical activity, sleep optimization and cognitive training,” they wrote.Commenting on the study, Dr. Kaitlin Roke, director…
Colossal Biosciences as a company name was picked to engage children, says chief executive Ben Lamm.Credit: Colossal BiosciencesThe meaning behind our monikerColossal Biosciences, in Dallas, Texas, describes itself as the world’s first de-extinction company. It aims to revive lost species using CRISPR gene-editing technology, including the mammoth (Mammuthus spp.). It attracted controversy when it announced it has ‘de-extincted’ the dire wolf (Aenocyon dirus), a large-bodied wolf species that last roamed North America during the ice age that ended some 11,500 years ago. Its co-founders are technology entrepreneur Ben Lamm, Colossal’s chief executive, and George Church, the company’s genetics adviser, who…