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This webinar will be hosted live and available on-demandFriday, February 27th, 202612:30 – 2:00 PM ETImmunology research is rapidly evolving, with emerging technologies such as single-cell approaches, multiplexed imaging methods, multiomic profiling, and computational modeling enabling unprecedented views of the immune system. By applying these innovations, scientists are uncovering functional shifts and patterns in the immune system across health and disease, revealing new insights into how immunity develops and changes over time.In this webinar brought to you by The Scientist, Claire Gustafson will highlight cutting-edge tools and technologies that are advancing immunology research.Topics to be coveredUsing multiomic profiling to chart…

Pancreatic cancer, 3D illustration. [Mohammed Haneefa Nizamudeen/Getty Images] Researchers at Tokyo University of Science have identified a gene that appears to act as a tumor suppressor pancreatic ductal adenocarcinoma (PDAC), the most common form of pancreatic cancer. Their research, published in Cancer Genomics & Proteomics, analyzed large-scale genomic and clinical data sets and found that low expression of the gene CTD nuclear membrane phosphatase 1 (CTDNEP1) was associated with important oncogenic mutations, immune suppression of the tumor microenvironment, and poor patient survival, which point to the potential that the gene plays a role in slowing tumor progression and influencing anti-tumor…

The ISAPP board of directors is pleased to announce the selection of the winner of the 2026 Sanders Award for Advancing Biotic Science: Prof. David Mills PhD, a Distinguished Professor and researcher at University of California, Davis, USA. Through his 30-year career in microbiology, Prof. Mills has been a leader in elucidating the genomics of lactic acid bacteria and bifidobacteria, and has worked diligently to translate scientific insights into practical applications. Early in his career, Prof. Mills led numerous pioneering efforts to sequence lactic acid bacterial genomes and became well known for his work on the wine-associated bacterium Oenococcus oeni…

New research suggests Junevity’s siRNA approach could reverse age-related cellular decline without triggering dedifferentiation or cancer-related pathways. A new paper published in the Proceedings of the National Academy of Sciences appears to validate the cellular reprogramming approach being developed by longevity biotech Junevity. The study describes research conducted at UCSF that led to the foundation of the company, and provides peer-reviewed evidence that aging-related cellular decline can be reversed by repressing a single transcription factor. The findings add credibility to Junevity’s vision of translating cellular rejuvenation into drugs capable of increasing human lifespan and healthspan. The company’s research focuses on…

Agenus closed its previously disclosed $141 million strategic collaboration with Zydus Lifesciences, which is designed to accelerate global development and potential commercialization of Agenus’s botensilimab and balstilimab (BOT+BAL) immunotherapy combination program. The collaboration provides Agenus with strategic capital and committed, long-term biologics manufacturing capacity in the United States to support BOT+BAL clinical development, authorized early access pathways, and commercial supply preparation, noted Garo Armen, PhD, chairman and CEO of Agenus. As part of the collaboration, Agenus has granted Zydus exclusive rights to develop and commercialize BOT and BAL in India and Sri Lanka, with Agenus eligible to receive royalties on…

Scientists revealed how beige fat restrains an enzyme that promotes blood vessel constriction.Image credit:Weslie R. and William H. Janeway, Laboratory of Molecular Metabolism at The Rockefeller UniversityDespite the message many fitness influencers keep trying to push, fats are essential for the body to function properly. Too little and issues with hormone production, vitamin absorption, and nerve function might crop up. But too much fat isn’t good either. Decades of patient data unequivocally show that obesity increases the risk of hypertension, which subsequently raises the likelihood of developing cardiovascular diseases and strokes.1 But not all fat is the same. It’s the…

Credit: Callista Images/Getty Images Researchers at Baylor College of Medicine have developed a new approach to isolating circulating tumor cells (CTCs) from liquid biopsies of patients with triple-negative breast cancer (TNBC). Through the identification of four new cell surface markers specific to TNBC cells, this work could address a major limitation that has historically prevented the use of CTCs in the diagnosis and monitoring of TNBC.  “The new markers detected cells that standard methods missed,” said Chonghui Cheng, MD, PhD, professor of molecular and human genetics at the Lester and Sue Smith Breast Center at the Baylor College of Medicine…

Officials at Cellares said the company has secured a site and signed a long-term lease for a new integrated development and manufacturing organization (IDMO) Smart Factory at Leiden Bio Science Park (LBSP) with Dura Vermeer Commercieel Vastgoed. The facility will serve as Cellares’ European headquarters and expand the company’s global manufacturing network with dedicated regional capacity, adds a company spokesperson. Cell therapy manufacturing is patient-specific and time-sensitive, making regional production capacity increasingly important as programs advance from clinical development toward commercial supply. The new Netherlands hub is designed to provide European drug developers with access to automated manufacturing infrastructure, while…

Credit: Ivan-balvan/Getty Images People with color blindness are more likely to die after being diagnosed with bladder cancer than those with full color vision, researchers have discovered. The investigators suggest that some patients with color vision deficiency (CVD) may not be able to spot blood in their urine, which is an early warning sign of that cancer. The findings suggest that these patients may therefore benefit from extra screening. “The fact that bladder cancer is more prevalent in men, who also have an increased prevalence of CVD, makes such a study potentially important,” commented Masahito Jimbo, PhD, from the University of…

While traditional gel electrophoresis remains foundational in molecular biology, its slow, labor-intensive workflow no longer meets the speed and flexibility required in today’s labs. Motivated by the need for faster, more convenient analysis, scientists developed the FlashGel® System—a ready-to-use solution that significantly reduces hands-on time and delivers results in minutes.Hugh WhiteResearch and DevelopmentTechnical MarketingLonzaIn this Innovation Spotlight, Hugh White from Lonza discusses the system’s advantages, including its precast, optimized gels, and highlights recent updates that introduce greater versatility and extend the gels’ shelf life.In what ways is traditional agarose gel electrophoresis lacking?Traditional agarose gel electrophoresis, while reliable and widely used,…