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New collaboration aims to bring clarity, credibility and cohesion to the fast-growing longevity clinic ecosystem. Longevity.Technology and the International Institute for Longevity (IIOL) have announced a collaboration designed to bring greater structure and transparency to the expanding longevity-clinic landscape. The partnership pairs Longevity.Technology’s work in data curation, market analysis and sector mapping with IIOL’s focus on operational standards, evidence-based practice and industry representation. It arrives at a moment when longevity clinics are proliferating globally and when clinics, investors and patients alike are seeking clearer indications of quality, scope and scientific rigor. The initiative sits alongside Longevity Clinics World (LCW) –…
Credit: vaaseenaa/Getty Images Gut bacteria metabolize nutrients from plants with known health benefits differently in healthy and diseased people, according to research that could help create health-promoting diets tailored for a particular individual. Large-scale systematic mapping showed that gut microbial enzymes were able to biotransform hundreds of dietary, plant-derived food compounds—or phytonutrients—according to the study in Nature Microbiology. However, this metabolic potential varied according to the health of a person and suggested that biotransformational potential was affected by disease. It also underscored the central role of gut microbiota in mediating the health effects of diet, reported Lu Zhang, PhD, from…
Avance Biosciences opened its new Potency and Cell-Based Assay Center of Excellence, a purpose-built facility designed to expand and centralize the company’s capabilities in potency and functional cell-based assays under GMP compliance. Located in Houston, the Center supports clients across the development and manufacturing of biologics, RNA therapeutics, vaccines, and cell and gene therapies, according to company officials, who add that the Center is equipped with advanced instrumentation and led by experienced cell biologists and assay development specialists. Key service offerings include: Custom potency assay development tailored to product mechanisms of action Fit-for-purpose potency assay qualification and/or validation in accordance with…
Curiosity comes alive when citizen scientists help map microbes, track wildlife, and uncover the unexpected.Image credit:©iStock.com, Akarawut LohacharoenvanichAcross the globe, citizen scientists are lending their eyes, hands, and curiosity to research. In some of these efforts, volunteers play the role of colorful creatures to study social behavior and disease. In others, they send photos and samples of mysterious household slime to help uncover new microbes. Many citizen scientists head outdoors to catch insects that will enrich global DNA databases, while others contribute vaginal swabs that expand our understanding of what a healthy human microbiome looks like. These initiatives demonstrate the…
Professor John Beard reflects on the societal shifts needed for humanity to capitalize on the healthspan dividend. This week’s release of the second edition of the Global Healthspan Report by Hevolution Foundation marks a pivotal moment for field that is increasingly becoming a key topic of discussion at scientific, corporate and political levels. Built on global surveys, investment analysis, expert interviews and extensive research, the 2025 report shifts the conversation beyond defining healthspan to interrogating how far progress has truly advanced – and what must change to accelerate it. Longevity.Technology: Among the key opinion leaders contributing to the Hevolution report…
Scientists from the University of Maryland School of Medicine (UMSOM) and the University of Alabama at Birmingham’s Heersink School of Medicine say they have identified a bacterial enzyme that may be the reason some people get heart complications with pneumonia, while others do not. Since enzymes create chemical reactions to help bacteria survive, grow, and sometimes attack tissues, the researchers understood this particular enzyme, named zmpB, could become a target for future vaccines or drug therapies. They published their findings in Cell Reports. “About one in five people hospitalized with pneumonia will suffer a life-threatening adverse cardiac event and, even…
With programs targeting Alzheimer’s and Parkinson’s, company targets several major drivers of neurodegenerative disease. US biotech SciNeuro Pharmaceuticals has secured $53 million in new financing to accelerate development of its pipeline of therapies aimed at the underlying biology of neurodegenerative diseases. The Rockville, MD-based biotech has built its strategy around three mechanistic pillars implicated in neurodegenerative disease pathology: neurovascular inflammation, proteinopathy and dysregulated neuro-immune signaling. SciNeuro is building a pipeline that spans small molecules and antisense oligonucleotides targeting Alzheimer’s, Parkinson’s and other CNS diseases. The company says each of its programs is tied to genetically or mechanistically validated pathways, beginning…
Colon cancer. Cancer attacking cell. Colon disease concept Circulating tumor (ct)DNA could be used to identify which patients with stage III colon cancer (CRC) are most likely to benefit from treatment with the cyclooxygenase (COX) inhibitor celecoxib in addition to conventional chemotherapy, say researchers. “These findings are the first to implicate MRD [molecular residual disease], as assessed by ctDNA, as a potential predictor of therapeutic response to adjuvant COX-inhibition in CRC,” write George Zhanh, MD, MPH, (Brigham and Women’s Hospital, Boston, Massachusetts) and study co-authors of in JAMA Oncology. They explain that although ctDNA has a well-established role in predicting…
Cell culture is a ubiquitous technique used in laboratories across a diverse range of fields and sectors. There is a growing need to standardize and streamline workflows, to ensure the reliability and reproducibility of data. Scientists engaged in cell culture research must mitigate the risks associated with inconsistent, underperforming, or unreliable reagents and equipment.Download this infographic to learn about the basics of cell culture essentials, including classic and novel cell culture media, buffers, reagents, filtration devices, and cultureware that streamline and workflows and optimize reliability.
New open-science consortium seeks to quantify joy as a biological input with real and measurable healthspan relevance. Frontier Towers, San Francisco, has become an unexpectedly apt setting for an experiment that edges longevity medicine into new conceptual terrain. A consortium featuring neurotechnology firms, AI platforms, decentralised research groups and what might broadly be termed the city’s evidence-inclined biohacking community has launched what it calls the first attempt to create a unified metric for joy, connection and synchrony. The initiative, known as JoyScore, draws on the growing body of research that positions social and emotional experiences as influential modulators of stress…