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A brain scan of a person with Huntington’s disease, which causes a loss of brain volume as neurons are killed off by the accumulation of a mutant protein.Credit: Zephyr/Science Photo LibraryA one-time gene therapy can markedly slow the progression of Huntington’s disease, potentially paving the way for the first ever treatment to alter the course of this rare, inherited brain disorder.In a small trial of 29 people who were in the early stages of Huntington’s-related decline, participants who received a high dose of the therapy directly into their brains saw the disease slow by 75% over three years, compared with…

Neptune is the planet of illusion, dreams, and spirituality, and while those areas of our life are important, they’re extremely abstract and difficult to pin down. That’s the nature of Pisces, too, so earthly communication just doesn’t cut it for them.

Authors whose work has been retracted often build larger networks than do those without retractions, a study found.Credit: Halfpoint/iStock via GettyRetractions can have profound effects on researchers’ careers, sometimes in unexpected ways, a study that tracked the career trajectories of thousands of authors has found. The range of experiences that authors go through raises questions about whether this mechanism — an important part of the scientific process — is working as intended, says co-author Shahan Ali Memon, an information scientist at the University of Washington in Seattle. “Retractions serve a crucial role in maintaining the credibility of scientific evidence, but…

Tomatoes are loved in the U.S., but drought and climate change threaten their supply.Hydroponics and vertical farming could use up to 90% less water while producing quality tomatoes.High costs and labor needs limit growth, but greenhouses could shape the future of farming. From ketchup on burgers to the sauce on pizza, tomatoes find their way into many of America’s favorite foods. In fact, tomatoes are one of the most-eaten vegetables in the U.S., second only to potatoes. The average American eats more than 30 pounds of them each year. Because they’re packed with the antioxidant lycopene, eating tomatoes regularly can…

Nearly 1.4 million Oster French Door Countertop Ovens recalled after 95 burn reports.The mini ovens were sold at Costco, Walmart, Amazon and more.Contact the company for a repair kit if you have a recalled oven on hand. A recall was just announced on various countertop and air fryer oven models, according to the U.S. Consumer Product Safety Commission (CPSC). This follows multiple reports of burn injuries. Approximately 1,394,195 Oster French Door Countertop Ovens were recalled across the U.S. and Canada. The mini ovens with one the following model numbers were affected: TSSTTVFDXL, TSSTTVFDDG, TSSTTVFDMAF, TSSTTVFDDGDS, TSSTTVFDDAF-033, TSSTTVFDXLPP-033 and TSSTTVFDDAF. These…

View eBook   Biomanufacturing is entering a new era, driven by urgent demands for lower drug costs, faster development timelines, and more sustainable operations. The traditional batch-based models that once defined monoclonal antibody (mAb) production are no longer sufficient to meet the growing complexity of today’s therapeutic pipeline or the global need for affordable access. Process intensification (PI) is emerging as a transformative response. Rather than viewing PI as a single technology or step, industry leaders are increasingly embracing it as a holistic, stepwise strategy to reimagine the entire biomanufacturing process, from upstream scale-up to downstream purification and beyond. PI…

This isn’t your regular scale.

When you sleep, your tongue and surrounding throat muscles relax, which helps air flow to your lungs.If you have OSA, though, your airway is narrow. So when your tongue and surrounding throat tissues relax, sleep apnea can temporarily block the flow of air and cause brief pauses in breathing.[1]How does sleep position come into play? Lying on your back, for example, can cause your tongue and throat tissues to collapse further, making it even harder for air to flow to your lungs, says Stephen Carstensen, DDS, a dental sleep specialist who treats sleep-related breathing disorders in Bellevue, Washington. This is…

A porous sponge system streamlines T cell activation and transduction into a single step, reducing workflow complexity while maintaining efficiency without chemical enhancers or other transduction-enhancing methods.Image credit:©iStock, luismmolinaViruses are effective tools for delivering genetic material into cells, and scientists have taken advantage of viral transduction in numerous ways, such as constructing chimeric antigen receptor (CAR) T cells for cancer therapy. However, traditional methods of T cell transduction are often error prone, time consuming, and require large amounts of material.In May 2025, Takara Bio USA rolled out the Lenti‑X T‑Cell Transduction Sponge to address these cellular engineering pain points. The company…

A crime laboratory officer removes material from the house of the prime suspect in the Gilgo Beach killings.Credit: Jeenah Moon/AP Photo/AlamyA judge in New York rejected a request on 23 September to disqualify the use of cutting-edge DNA sequencing as evidence in a case against an alleged serial killer. The ruling paves the way for a type of DNA analysis known as whole-genome sequencing — used to decipher ancient DNA in fossilized remains, for example — to be admitted as evidence in US criminal trials.“This is a big step forward for the use of DNA evidence, because it will allow…