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AbstractObjective To assess the quality, biases, and validity of evidence on maternal paracetamol (acetaminophen) use during pregnancy and the risk of autism spectrum disorder (referred to as autism) and attention deficit/hyperactivity disorder (ADHD) in offspring.Design Umbrella review of systematic reviews.Data sources Medline, Embase, PsycINFO, and the Cochrane Database of Systematic Reviews, along with grey literature, Epistemonikos, and the reference lists of included studies (inception to 30 September 2025).Inclusion criteria Systematic reviews of randomised trials and cohort, case-control, or cross sectional studies that reported maternal paracetamol use during pregnancy and the diagnosis of autism or ADHD in offspring. Details of the…
The link between a sedentary lifestyle and an increased risk of Alzheimer’s disease is becoming clearer.Being active benefits your sleep, mood, heart health and inflammation, helping to reduce your risk of Alzheimer’s. A brain-healthy diet, mental engagement and social connection also help to keep your mind healthy. We all want to stay sharp as we age, and for that reason, many of us include tried-and-true habits, like eating berries and limiting alcohol, to support our brain health. But what if a simple, everyday habit—something many of us do without a second thought—could be quietly putting our brains at risk? It’s a…
Doing less cardio and eating more fats are two “bad” things that can help reduce visceral fat.Eating healthy fats and consuming enough calories supports long-term fat loss.Getting enough rest and lowering stress are also effective things to do for visceral fat loss. Visceral fat is that vexing, stubborn fat that hangs out around your abdomen and doesn’t seem to budge. Unlike subcutaneous fat, which you can see and pinch, you can’t actually feel visceral fat. This fat doesn’t just make your abdomen bigger; it can also cause health issues. Research suggests that having higher levels of visceral fat increases the risk…
Protein is essential for strengthening the immune system, as it works with key immunity-boosting micronutrients, such as vitamins A, C, and E, selenium, and zinc, says Julie Cunningham, RD, a certified diabetes care and education specialist based in Hendersonville, North Carolina.With that in mind, consider the humble chickpea, a plant-based protein source that’s also a powerhouse when it comes to zinc. A standard 1-cup serving has 0.9 milligrams (mg) of zinc.[2] For context, men should aim for 11 mg of zinc daily, and women should get 8 mg.[3]Zinc can help strengthen the immune system to ward off infectious disease. The reverse is…
Generative AI biotech unveils portfolio of novel cardiometabolic candidates aimed at tackling the biology of aging. Insilico Medicine has announced a new wave of cardiometabolic programs discovered through its proprietary generative AI platform, Pharma.AI, positioning metabolic optimization as a cornerstone of longevity-focused medicine. Revealed at BIO-Europe 2025, the expanded portfolio includes eight oral small molecules designed to target established and moderately novel pathways involved in inflammation, insulin sensitivity and energy metabolism. These include oral GLP-1 receptor agonists (GLP-1RAs) with improved safety and pharmacokinetics, a selective NLRP3 inhibitor for inflammatory and neurodegenerative disease, and candidates directed at NR3C1, GIPR, Amylin, APJ…
After entering China via cross-border e-commerce in 2018, the brand reached cumulative sales of USD100m in the market last year.According to Derek Liu, CEO of Noromega, the expansion of sales channels, particularly livestreaming platforms, was the main contributor to the brand’s rapid growth in China. “We wanted to expand to as many sales channels as possible because the Chinese market is so big, and there are so many different channels, such as e-commerce platforms like Tmall and social commerce platforms like Douyin,” Liu told NutraIngredients at Vitafoods Asia 2025 in Bangkok. “In China, we have around 150 staff working in…
After a busy day, there’s nothing better than coming home to a dinner that’s already done—and smells incredible. These highly-rated vegetarian slow cooker recipes are full of nourishing produce, making them delicious options whether you’re fully vegetarian or just looking to incorporate meatless meals in your diet. Try options like our Slow-Cooker Sun-Dried Tomato and Spinach Pasta Bake or our Slow-Cooker Three-Bean Chili Mac for a satisfying meal that comes together easily. Love any of these recipes? Join MyRecipes to save, search and organize your EatingWell recipes all in one place. It’s free! Slow-Cooker Sun-Dried Tomato and Spinach Pasta Bake…
Thanksgiving is all about the food: turkey, ham, stuffing, cranberry sauce, mashed potatoes, mac and cheese, sweet potatoes, roasted veggies and pumpkin pie … OK, we’ll stop making you drool. But clearly we’re counting down the days to enjoy our favorite comfort meal of the year and days’ worth of delicious leftovers. For the hosts out there, the holiday can be a little stressful as you finish up cooking and your family is hovering around the kitchen. One of our favorite ways to distract hungry guests (besides the football game) is to put out a humble snack for munching. You…
Investors in Recursion (NASDAQ: RXRX) seemed only mildly fazed by Wednesday’s series of company announcements. The artificial intelligence (AI)-based drug developer’s stock barely moved on Wednesday, then dropped on Thursday, after reporting mixed third-quarter results, setting the stage for future pipeline announcements, and announcing a change at the top. Recursion finished the third quarter with a net loss of $162.253 million, 69% higher than the $95.841 million net loss in Q3 2024, driven by higher R&D and business costs. But the company’s earnings per share (EPS) of negative 36 cents beat analyst consensus forecasts of a slightly worse negative 37…
Historic vote heralds one of the largest ever public investments in neuroscience and neurodegenerative disease research. This week, voters in Texas overwhelmingly approved a ballot measure that allocates a staggering $3 billion in state funds to brain health research over the next decade. With more than two-thirds of voters in favor, the approval of “Proposition 14” reportedly represents the largest state-level financial commitment to neurodegenerative disease research in US history. The measure will support the Dementia Prevention and Research Institute of Texas (DPRIT), a fund created earlier this year designed to accelerate discoveries in neuroscience and neurodegenerative diseases such as…