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Late last year, a viral study revealed that nearly half of US tap water contains PFAS (also known as “forever chemicals”). And, while that may just sound like a buzzy headline, these contaminants have actually been linked to serious health issues, such as cancer, liver damage, and immune system disruptions. 

uniQure reported positive topline data from the pivotal Phase I/II study of AMT-130 for the treatment of Huntington’s disease. The study met its prespecified primary endpoint, with high-dose AMT-130 demonstrating a statistically significant slowing of disease progression as measured by the composite Unified Huntington’s Disease Rating Scale (cUHDRS*) at 36 months compared to a propensity score-matched external control, according to the company. The study also met a key secondary endpoint by achieving statistically significant slowing of disease progression as measured by Total Functional Capacity (TFC) at 36 months compared to a propensity score-matched external control. Neuronal inclusions in Huntington’s disease,…

Are you feeling tired, run-down, or drained? Trying to pinpoint the exact cause behind those feelings may feel just as fatiguing. Yes, sleep and hydration should be the first two things you look at and evaluate, but if those habits are buttoned up, then it’s time to look elsewhere.

Teamwork and hands-on learning underpins NMITE’s pedagogy ethos.Credit: NMITEEight hundred years ago, a group of scholars walked out of the University of Oxford after a bitter and violent dispute with local townspeople. At a fork in the road, the scholars might have turned left and founded a university in Hereford, a cathedral city 106 kilometres away. Instead, they turned right and established the University of Cambridge, triggering an academic rivalry between the two institutions that endures to this day.The future of universities“It’s a fun ‘what if’,” said Jesse Norman of this apocryphal story about a university that might have been.Norman,…

Credit: jxfzsy/Getty Images A study by the Molecular Oncology Research Center (CPOM) at Hospital de Amor in Barretos, Brazil, has identified distinct immune signatures in pediatric germ cell tumors (GCTs) that may guide the development of more targeted and less toxic treatments for children. Published in Frontiers in Immunology, the research analyzed the expression of about 800 immune-related genes and identified the types and behaviors of immune cells present in different GCT subtypes. “Germ cell tumors can occur in adults as well as children and adolescents. In the pediatric population, they’re very rare, accounting for about three percent of tumors.…

Circulating tumor cells were first described in 1869 by Thomas Ashworth, an Australian pathologist who observed them in a peripheral blood sample taken from a patient with metastatic cancer.1 They have since been detected in a range of tumor types, including breast, prostate, colorectal, ovarian, lung, liver, gastric, and pancreatic cancers, as well as melanoma.2Researchers and clinicians can use circulating tumor cells to study cancer in a non-invasive way, gaining valuable insights into the biology of tumors. In this article, we explore what these cells are, the challenges associated with studying them, and how they enable scientists to diagnose cancer…

Court sports demand quick moves, jumping and shuffling, raising risk of injury with the wrong shoes. Podiatrists recommend the ASICS Gel-Resolution X as the top shoe for tennis and pickleball. Choose shoes with shock absorption, lateral stability and traction for court play. If you’ve ever enjoyed a tennis or pickleball match, you know they demand quick bursts and rapid direction changes. Whether you’re sprinting after a shot, shuffling side-to-side or jumping for a serve, your feet are always in motion. That’s why shoes for these sports call for lateral support, stability and traction to help prevent slips or ankle rolls.…

Blackberries are a delicious yet nutritious fruit to snack on. So while you might not think that there are any downsides to eating them, you might be surprised to learn about a few disadvantages that may occur if you munch on too many. Here’s what you need to know. Changes in Urine Color Typically, urine color should range from clear to pale golden-yellow, according to Mayo Clinic . But if you look down at the toilet after a trip to the bathroom and notice a different color, it may cause some concern. When you eat too many blackberries, it can…

No outdoor adventure should be undertaken without the proper gear, especially now that fall is here. Luckily, REI has everything you need to stay active and warm year-round, and at prices you can’t help but appreciate. For a limited time, I found a Stanley water bottle, Vuori joggers, Brooks running shoes and more on sale for up to 33% off. Score these cold-weather exercise essentials before they sell out.   7 Best REI Deals Right Now  Brooks Ghost Max 2 Road-Running Shoes, $121, was $150  Hoka Mach X 2 Road-Running Shoes, $153, was $190  Stanley IceFlow AeroLight Water Bottle, $26, was…

Hundreds of GP surgeries in England are not fit for purpose and cannot meet growing patient demand, the BMA has warned.A BMA survey of almost 2000 GPs and practice managers revealed widespread concern about the physical state of surgeries in England.1Participating practices reported problems such as mould growing in waiting rooms, cracked walls in treatment rooms, and inadequate space for staff to work in. Only half of respondents (50%) said that their premises were suitable for present use, while 83% believed that their surgery could not meet future demand.Over 80% of respondents reported not having enough space for additional staff,…