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Blackberries are a delicious yet nutritious fruit to snack on. So while you might not think that there are any downsides to eating them, you might be surprised to learn about a few disadvantages that may occur if you munch on too many. Here’s what you need to know. Changes in Urine Color Typically, urine color should range from clear to pale golden-yellow, according to Mayo Clinic . But if you look down at the toilet after a trip to the bathroom and notice a different color, it may cause some concern. When you eat too many blackberries, it can…

No outdoor adventure should be undertaken without the proper gear, especially now that fall is here. Luckily, REI has everything you need to stay active and warm year-round, and at prices you can’t help but appreciate. For a limited time, I found a Stanley water bottle, Vuori joggers, Brooks running shoes and more on sale for up to 33% off. Score these cold-weather exercise essentials before they sell out.   7 Best REI Deals Right Now  Brooks Ghost Max 2 Road-Running Shoes, $121, was $150  Hoka Mach X 2 Road-Running Shoes, $153, was $190  Stanley IceFlow AeroLight Water Bottle, $26, was…

Hundreds of GP surgeries in England are not fit for purpose and cannot meet growing patient demand, the BMA has warned.A BMA survey of almost 2000 GPs and practice managers revealed widespread concern about the physical state of surgeries in England.1Participating practices reported problems such as mould growing in waiting rooms, cracked walls in treatment rooms, and inadequate space for staff to work in. Only half of respondents (50%) said that their premises were suitable for present use, while 83% believed that their surgery could not meet future demand.Over 80% of respondents reported not having enough space for additional staff,…

Nature, Published online: 24 September 2025; doi:10.1038/d41586-025-02593-9Tick-borne encephalitis virus can infect the nervous system and cause life-threatening illness. Finding the cellular gateway it uses could transform prevention and treatment.

RESEARCH BRIEFINGS 24 September 2025 Earth’s most diverse biological entities are the viruses that infect bacteria, called bacteriophages (phages). They are rich resources for discovering proteins and tools for biotechnology, but many phage–bacteria systems resist genetic manipulation. Silencing phage genes in a non-genetic way with short synthetic nucleic acids offers a solution.

Credit: PIXOLOGICSTUDIO /SCIENCE PHOTO LIBRARY/ Getty Images A particular immune system signature present in the antibodies of some people could leave them at increased risk of dengue fever after vaccination, researchers reported. The findings, in Science Translational Medicine, demonstrated how both the quality and quantity of antibodies generated by vaccines can affect their effectiveness. The study found that people with a particular modification in their immunoglobulin (IgG) antibodies were susceptible to reinfection. The research highlights immune factors that could be targeted in future vaccine strategies for both dengue and other diseases. “Overall, these findings emphasize the importance of considering both…

The positive improvements reported in adults were primarily in non-verbal memory and sleep disturbance, with no differences in verbal memory or executive function compared to placebo.“This is the first controlled study demonstrating the cognitive-enhancing and sleep-promoting effects of stand-alone supplementation with tocotrienols,” wrote researchers at Clinical Research Australia, Murdoch University and BGG Americas, which funded the study.Dr. Adrian Lopresti, lead authors and managing director of Clinical Research Australia, told NutraIngredients that there is already some research in the literature to support an association between eating vitamin E-rich foods and having higher blood concentrations of vitamin E with better cognitive health,…

Robertsonian chromosomes (ROB) are a type of structurally variant chromosome that is created when two chromosomes fuse together to form an unusual bond. Found commonly in nature, these chromosomes are present in about 1 in 800 humans, and while carriers may be asymptomatic, ROBs can underlie infertility, and contribute to trisomy. Scientists at the Stowers Institute for Medical Research, led by postdoctoral research associate Leonardo Gomes de Lima, PhD, have now identified the precise location where human chromosomes break and recombine to form Robertsonian chromosomes. Their findings explain how these rearrangements form and remain stable—but also point to how repetitive…

Study highlights functional preservation in patients and signals the potential for pre-symptomatic intervention. For decades Huntington’s disease has stood as both a genetic certainty and a model of accelerated cellular aging; new clinical trial data now show that decline can be delayed. Results released by uniQure demonstrate that AMT-130, an experimental gene therapy delivered in a single neurosurgical session, slowed clinical progression by 75 percent over three years in treated patients [1]. The pivotal Phase I/II study compared treated patients with propensity score-matched external controls from the Enroll-HD dataset. High-dose AMT-130 met its primary endpoint, showing a statistically significant slowing…

Hot air drying — a cheap and relatively easy preservation technique — improves the availability of key nutrients and plant compounds in microgreens that benefit health, according to new food research. When kept fresh, these highly nutritious young seedlings of cruciferous vegetables like radish, broccoli, and kale are highly perishable and lose nutritional value quickly. Microgreens contain nutrients such as vitamins, minerals, and bioactive antioxidants, like polyphenols and glucosinolates.“Microgreens increasingly are popular due to their high concentrations of health-promoting compounds, but their benefits have been limited because they’re highly perishable, lasting only one to two days at room temperature and…