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uniQure’s “game changing” data announced in September, which showed significant slowing of Huntington’s disease (HD) progression in patients treated with its gene therapy candidate AMT-130, may not be enough to secure FDA approval. We also discuss Recursion’s pivotal leadership transitions, as Najat Khan, PhD, chief R&D officer and chief commercial officer, is set to take over as the company’s CEO effective January 1. The AI drug developer has made big bets filling the biology data gap and recently announced a “Google Map of the brain” to advance neurodegenerative disease targets. In open-source AI for drug discovery, the release of the…

Monthly GLP-1 costs will drop to $350 or less under TrumpRx starting in 2026.Medicare patients may pay as little as $50/month for Wegovy and Zepbound.GLP-1 drugs are one part of a healthy lifestyle, not a quick fix for weight loss. The Trump Administration has just announced price agreements with pharmaceutical companies Novo Nordisk and Eli Lilly that will make some GLP-1s more affordable for Americans, including people enrolled in Medicare. The increased accessibility of these drugs, like Ozempic, may see further downward shifts in adult obesity rates. Here’s what to know. According to the Gallup National Health and Well-Being Index,…

A trust has axed free tea and coffee for its staff in an attempt to save money.University Hospital Southampton NHS Foundation Trust confirmed that it has stopped providing milk, tea, and coffee for most staff in order to save £50 000 a year. This follows an announcement in May that the trust was cutting 750 jobs from its workforce of around 13 000 to save £110m from its £1.3bn turnover.The decision was made as part of wider requirements for the trust to live within its financial means, it said.The BMJ understands that the trust initially planned to pause free refreshments for all…

Credit: Nanoclustering / Science Photo Library / Getty Images The process of variable translation of mRNAs through alternative start codon selection produces multiple protein variants with distinct cellular destinations and has been associated with mitochondrial function and rare diseases. Investigators at the Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology, and Boston Children’s Hospital identified that alternative start codons can determine a protein’s localization to the mitochondria or its retention in the cytosol and nucleus. This mechanism, detailed in a Molecular Cell research article, has medical implications, as rare disease variants can selectively impair one isoform while leaving another…

The event, spanning two full days at the Park Plaza Victoria London, will cover a range of scientific and business topics related to the booming opportunity for nutrition to extend healthspan. Companies in the room include Nestlé, L’Oréal, The Vitamin Shoppe, Thorne, PepsiCo, Estée Lauder, GNC, Avea, the Buck Institute for Research on Aging, the National University of Singapore, Elysium Health, Danone and many more.Nutra Healthspan Summit program The summit opens on Wednesday, Nov. 12, with registration at 8:30 a.m. Morning sessions starting at 9:00 a.m. will explore the state of the market and unpack the 12 hallmarks of aging.…

And considering your ruling planet, Mercury, is retrograding in the relationship sector of your chart this month, slowing down is exactly what you need right now. Uranus, the planet of change, is retrograde in your first house of self until November 7, and then it backspins into Taurus and your 12th house of endings for the rest of this month. Plus, the planet of luck goes retrograde in your second house of self worth on November 11.

As the gummy supplement market continues its rapid expansion, many formulators face a persistent challenge — how to deliver optimal absorption of minerals without compromising taste or texture. By leveraging micronized citrate salts of magnesium and calcium, Jungbunzlauer says it can help brands create gummies that are smooth, flavorful, and highly bioavailable.Ahead of the company’s upcoming webinar, titled “Better gummies, better absorption: formulating gummies with organic mineral salts,” Nutrition Insight sits down with Emily Orr, Jungbunzlauer’s senior food scientist in application development and speaker at the webinar.Orr explains how the company’s next-generation ingredients allow brands to balance functionality with sensory…

RESEARCH HIGHLIGHT 07 November 2025 Dimming of the starlight from RZ Piscium reveals that 24 unseen bodies are whizzing around the star.

Colon cancer is the fourth leading cause of cancer deaths in the U.S.Eating an anti-inflammatory diet is linked with a 16% lower risk of colon cancer in a new study.Anti-inflammatory foods like fermented dairy, produce and healthy fats may help lower risk. Colorectal cancer (CRC), cancer of the rectum and/or colon (large intestine), is common. In fact, it’s the fourth most common type of cancer, and the fourth leading cause of cancer-related deaths in the U.S. Researchers are continually looking for lifestyle behaviors that influence cancer, including colorectal cancer. One of these behaviors is what we eat and how it…

Credit: Tumeggy / Science Photo Library / Getty Images The advent of mRNA vaccination, ignited by the COVID-19 pandemic, has sparked research to build the next generation of vaccine. Specifically, to address limitations of current mRNA vaccines—such as increasing vaccine potency and reducing toxicity. Now, a new delivery LNP, developed through sequential combinatorial chemistry and rational design, and based on a class of degradable, cyclic amino ionizable lipids, has been developed at MIT. The novel LNP could make mRNA vaccines more effective and potentially lower the cost per vaccine dose. In mouse studies, the researchers showed that an mRNA influenza…