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Last April, neuroscientist Sue Grigson received an e-mail from a man detailing his years-long struggle to kick addiction — first to opioids, and then to the very medication meant to help him quit.The man had stumbled on research by Grigson, suggesting that certain anti-obesity medications could help to reduce rats’ addiction to drugs such as heroin and fentanyl. He decided to try quitting again, this time while taking semaglutide, the blockbuster GLP-1 drug better known as Ozempic. “That’s when he wrote to me,” says Grigson, who works at Pennsylvania State University College of Medicine in Hershey. “He said that he…

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As an avid pickleball player who’s logged hundreds of hours on the court—from Duke’s collegiate team to LA’s competitive recreational scene—I understand what makes this sport special. So when I got the chance to sit down with Anna Leigh Waters, the No. 1 pickleball player in the world, I knew I was about to learn something. Not just about pickleball, but about what it takes to be the absolute best.

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I test kitchen gadgets for a living, and though I always have plenty of new gear, I always lean on  a select few items. One of the most essential tools on that list is my Microplane. A fine-toothed zester, this small but mighty tool does so many important things no other tool can: grate produce, whole spices, hard cheeses and more. I’ve always felt this way, but it was validating to know the queen of a well-stocked kitchen, Ina Garten, agrees!  Both Garten and Amy Poehler were talking about this tool during an episode of Poehler’s podcast, Good Hang with…

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A team of scientists at the Institute for Cell Biology (Cancer Research), University of Duisburg-Essen, has developed a simple method for the automated manufacture of induced pluripotent stem cell (iPSC)-derived lung organoids (iPSC-LuOrgs) in a stirred-tank bioreactor equipped with a membrane stirrer. The organoids, formed as miniature structures containing populations of lung cells, could potentially be used to test early-stage experimental drugs more effectively, without the use of animal material. The researchers, headed by Diana Klein, PhD, suggest the new production technology could revolutionize the development of treatments for lung disease. In the future, they suggest, it may even be…

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Study finds blood-derived bacterial metabolites that dampen inflammation and collagen breakdown in lab models. Researchers have uncovered a set of naturally occurring compounds produced by a little-known blood-resident bacterium that can dampen key biological drivers of skin aging in laboratory models. The findings, published in the Journal of Natural Products, hint at a surprising new source of longevity-relevant molecules and open an unexpected line of inquiry into how endogenous chemistry might be harnessed for skin health [1]. The study centers on Paracoccus sanguinis, a microbe isolated from human blood and notable largely because so few researchers have explored the metabolic…

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A combination of obesity and low levels of the nutrient choline could contribute to accelerated brain aging and potentially some early triggers of neurodegenerative diseases such as Alzheimer’s, according to a new study.Choline is well established as one of the most vital nutrients for a healthy body, so a lack of it, together with stresses associated with obesity, might act as warning signs for cognitive decline long before actual symptoms appear, according to researchers led by a team from Arizona State University (ASU).”This research adds to the growing evidence that choline is a valuable marker of metabolic and brain dysfunction…

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Collagen’s role in the United States nutrition market continues to shift as consumers seek multifunctional products that address appearance, mobility and long-term wellness in a single format. Speaking with NutraIngredients at SupplySide Global, Angie Rimel, marketing communications manager for North America at Gelita, outlined how category lines are blurring and why science-backed differentiation is becoming more important for brands navigating this broadened landscape.Collagen’s expanding position in holistic wellness“While collagen peptides have been popular in beauty for years, there is an understanding that these ingredients are more than skin deep…they are foundational for whole body vitality and performance,” Rimel said.This broader…

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With a focus on community-specific risks, this postdoc reveals the molecular roots of pancreatic cancer to guide personalized care.Image credit:The University of Texas at El Paso, ©iStock.com, JezperklauzenQ | Write a brief introduction to yourself including the lab you work in and your research background. I introduce myself as Zahid Rafiq. Currently, I am a postdoctoral fellow and a cancer pharmacologist serving for the School of Pharmacy here at the University of Texas, El Paso (UTEP). I am engaged in advanced pancreatic cancer research under a career transition program funded by the Cancer Prevention and Research Institute of Texas (CPRIT-TREC).…

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I walk approximately 10 miles a week. It’s the only form of cardio I can consistently do, and the only version that feels good for my body, given my chronic inflammation. Since I am sensitive to pain, I gravitate toward cushy, cloud-like sneakers for my walks because they help soften the impact of my steps. The first high cushion shoe I ever fell in love with was the Brooks Ghost Max. The original iteration of this now arguably coveted shoe, I ranted and raved so much that my sister ended up getting a pair of her own.  One year later,…

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Eating at night isn’t “good” or “bad”—it depends on your unique needs and goals.It can aid recovery and curb hunger for some, but cause weight gain or disrupt sleep for others.If you prefer an evening snack, choose one high in protein and fiber. Is the advice “Stop eating after 7 p.m.” a myth or a helpful strategy? The truth is, there’s no universal cutoff time. Whether late-night eating works against you—or fits into your routine—depends on your habits, hunger patterns and health goals. Here’s what registered dietitians say about the potential pros and cons of late-night eating, so you can…

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