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In what the White House is calling a historic step to lower drug costs, President Donald Trump announced new agreements with pharmaceutical manufacturers Eli Lilly and Novo Nordisk to slash prices and expand coverage of GLP-1 medications, including Ozempic, Wegovy, Zepbound, and Mounjaro.These changes come as part of the administration’s “Most-Favored-Nation” (MFN) policy, which the White House says is designed to ensure Americans pay no more than patients in other developed nations for the same drugs.[1]How the New Pricing WorksUnder the plan, monthly cash-pay prices will drop significantly when patients purchase the medication through a new federal portal called TrumpRx.gov.The…

Start your day with an anti-inflammatory breakfast like our Egg, Tomato & Feta Pita to support healthy aging.The dish offers nutrients like protein and fiber to preserve lean muscle mass and reduce inflammation as you age. This balanced meal comes together quickly, making it perfect for busy mornings. Inflammation can be tricky—it often develops quietly, without the obvious warning signs of other health issues. And while it’s easy to chalk up aches and pains to getting older, those symptoms aren’t always inevitable. The good news? Aging doesn’t have to mean discomfort. With the right foods, you can support your body from…

A new genetic engineering approach helped gene-edited plants grow faster. The researchers modified tomato plants, as well as soybean and a relative of tobacco.Image credit:© iStock.com, Katarina MolnarovaGene editing of plants enabled the production of more nutritionally rich rice and fortified tomatoes. But these innovations have often come about only through long, painstaking work. This process usually begins not with a flower or a tuber, but with a single plant cell. Researchers modify the cell’s DNA and then grow it into a plant. If it goes well, scientists can regenerate a plant from a cell in a few months; species…

Winter will be here before we know it, so we’re stocking up on cold-weather essentials while pieces are on sale. Luckily, REI just lowered prices on everything we’ll need to stay active and warm as temperatures drop, including Brooks running shoes, Vuori leggings, Columbia jackets and Smartwool socks. The best part? These end-of-fall, beginning-of-winter must-haves are discounted by up to 50% for a limited time in the brand’s clearance section.    Best REI Sales to Shop Ahead of Winter  Brooks Ghost Max 2 Running Shoes  REI The first step to staying motivated as the holidays approach and the weather gets colder…

Kamran Abbasi, editor in chiefThe BMJkabbasi{at}bmj.comThe climate crisis—remember that? I appreciate that our attention is being distracted elsewhere, but our greatest existential threat, other than Donald Trump’s ego, is ever spiralling rapidly out of control. The climate crisis no longer seems to matter (doi:10.1136/bmj.r2309), because politicians and corporations don’t want it to.1Has a newspaper, for example, ever devoted as much space to the climate crisis as to a discredited royal formerly known as prince? Will we ever care as much about the alarming statistics on global heating (doi:10.1136/bmj-2025-084675 doi:10.1136/bmj-2025-086218)23 as we do about Celebrity Traitors? Are we “faithfuls,” or are…

Ebinger, C. J. & Sleep, N. H. Cenozoic magmatism throughout East Africa resulting from impact of a single plume. Nature 395, 788–791 (1998).ADS  CAS  Google Scholar  Lin, S.-C., Kuo, B.-Y., Chiao, L.-Y. & van Keken, P. E. Thermal plume models and melt generation in East Africa: a dynamic modeling approach. Earth Planet. Sci. Lett. 237, 175–192 (2005).ADS  CAS  Google Scholar  Steinberger, B., Bredow, E., Lebedev, S., Schaeffer, A. & Torsvik, T. H. Widespread volcanism in the Greenland–North Atlantic region explained by the Iceland plume. Nat. Geosci. 12, 61–68 (2019).ADS  CAS  Google Scholar  George, R., Rogers, N. & Kelley, S. Earliest…

The trial, published in Dermatology and Therapy, tested Ritual’s HyaCera formulation in a demographically diverse cohort. The research was funded by the product manufacturer, Ritual, with partial financial contribution from the hyaluronic acid supplier, Kewpie. Study highlights whole-body skin improvementsThe study enrolled 63 healthy adults between the ages of 26 and 64, and the cohort was randomly assigned to receive either the supplement or a placebo once daily for 12 weeks. Skin changes were measured at multiple points using a combination of imaging technology, dermatologist evaluations and participant feedback.Participants in the supplement group reported significant reductions in crow’s feet wrinkles…

A new review compiles current insights into the various ways gut bacteria directly and indirectly influence sleep-wake cycles. The evidence indicates that gut microbiota dysbiosis (imbalance) both results from and contributes to sleep disturbances, which the authors warn can create vicious cycles that perpetuate poor sleep and associated health problems. The study points to microbiota-targeted interventions in pre-, pro-, and synbiotics as a “promising frontier” to address the global burden of sleep, with potential added benefits in brain health, metabolic function, and quality of life. Although sleep disorders affect millions worldwide, the full complexity of sleep regulation is not fully understood.…

Brain specimensHemispheres from five individuals (including half of the cerebrum, cerebellum and brainstem), were used in this study, following informed consent to use the tissue for research and the ethical approval for research by the National Research Ethics Service Committee London – Central. All hemispheres were fixed in 10% neutral buffered formalin (Fig. 1a). The laterality and demographics are summarized in Supplementary Table 1; the donors were neurologically normal, but one case had an undiagnosed, asymptomatic tumour (diameter roughly 10 mm) in the white matter, adjacent to the pars opercularis. This tumour did not pose issues in any of the processing…

Aspartame may influence brain health over time, potentially affecting neurotransmitters, mood and headaches, but more research is needed.A daily diet soda could impact the gut-brain connection, which may play a role in cravings, hunger cues and more.Enjoying diet soda occasionally is likely fine for most people, but choose water or other brain-supporting beverages more often. That crisp, bubbly sip of a diet soda can feel like a perfect afternoon pick-me-up or a satisfying mealtime companion. Since it contains zero sugar and zero calories, it seems like a harmless choice, especially compared to its sugary counterparts. But what does a daily…