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Hibernating animals go into a state of torpor wherein they lower their metabolic rate and internal temperature.Image credit:© iStock.com, Edwin_ButterAs leaves fall off the trees and temperatures grow bitingly cold, many animals prepare to hibernate for the winter. During this period, animals enter a state of torpor wherein they reduce their metabolic activity and lower their body temperature, which helps them conserve energy. Organisms can also enter other kinds of dormancy or adaptations to stressful environments that resemble hibernation. While studying these behaviors can teach scientists more about the unique biology of these animals, it can also inform human health…

Folate is a B vitamin that plays a role in many aspects of your health, including your brain. Low folate intake is linked to mood disorders, depression, dementia and neural tube defects during pregnancy.Folate is found in many foods, including leafy greens, beans and some fruits. As one of the most familiar B vitamins, folate plays a significant role in various aspects of your health. From the production of DNA and red blood cells to proper cell division and tissue growth, getting enough of this vital vitamin helps your body function at its best. Folate’s benefits stretch far beyond the cells,…

At the ongoing 20th Conference of the Parties (CoP) to the Convention on the International Trade in Endangered Species of Wild Fauna and Flora (CITES), 185 members gather in Uzbekistan to ensure international trade in wild species is sustainable, legal, and traceable. While trade in wild animals receives considerable public attention, the global wildlife trade monitoring NGO TRAFFIC cautions that wild plants may be overlooked. Based on the most recent data, TRAFFIC reported earlier this year that plant-derived medicinals comprised the largest share of CITES-related seizures (21%) in the EU. Many of these products were seized due to the lack…

Mouse proceduresNPp53 mice were maintained on a mixed C57BL/6-129Sv background and have been previously described7. Tamoxifen induction was performed in mice at 3–5 months of age by oral delivery of tamoxifen (MilliporeSigma; 100 mg kg–1 day–1 in corn oil) for 4 consecutive days as previously described58. The survival time of tumour-bearing mice in this study ranged from 228 to 435 days after tamoxifen induction (Supplementary Table 1). Mice were housed under specific pathogen-free conditions in individually ventilated autoclaved cages with irradiated feed and automated reverse-osmosis watering, under a 12-h dark–12-h light cycle with temperatures at 20–26 °C and humidity between 30 and 70%. All procedures followed…

Liver rejuvenation program produces a ‘lead payload’ as biotech begins its journey towards human clinical trials. After several years of development, longevity biotech NewLimit claims it is nearing its first “clinic-bound” epigenetic reprogramming medicine – a therapeutic payload designed to restore youthful function in hepatocytes (liver cells). In a recent update, head of research Jacob C Kimmel said the company plans to advance its candidate into human clinical studies in the next few years. Co-founded by Coinbase CEO Brian Armstrong, NewLimit was created to develop medicines that increase the number of healthy years in human life by targeting aging itself…

These dessert recipes are flavorful and delicious without any added sugar. Plus, they focus on ingredients that fight inflammation like nuts, berries and cherries so your tasty treat can help relieve symptoms like chronic fatigue  and joint pain. Recipes like our No-Added-Sugar Cherry Crumble and our Chocolate Strawberry Nice Cream are delights that you’ll want to make again and again. No-Added-Sugar Cherry Crumble Photographer: Grant Webster, Food Stylist: Lauren McAnelly, Prop Stylist: Gabriel Greco This no-sugar-added cherry crumble baked in ramekins is a great way to highlight the flavor of cherries in this naturally sweet snack. The crumble topping, made from…

MonkeysTwo adult male rhesus macaques (Macaca mulatta) participated in the experiment. The number of monkeys (2) follows previous work using similar approaches21. Monkeys Si and Ch were between 8 and 11 years old and weighed approximately 12.7 and 10.7 kg, respectively. All of the experimental procedures were approved by the Princeton University Institutional Animal Care and Use Committee (protocol, 3055) and were in accordance with the policies and procedures of the National Institutes of Health.Behavioural taskEach trial began with the monkeys fixating on a dot at the centre of the screen. During a fixation period lasting 500 ms–800 ms, the monkeys were required…

If you ate too much salt, drink water and eat potassium-rich foods to rebalance fluids fast.Get moving—sweating helps flush out excess sodium and reduce water retention.Focus on long-term habits like label reading, cooking at home, and smart snacking. If you’re thinking, “I ate too much salt— now what should I do?” you’re not alone. Whether it was a salty takeout dinner, a handful (or three) of chips or a night of ramen and snacks, sodium has a way of sneaking in. The average American eats about 3,400 milligrams of sodium a day—well above the recommended 2,300 milligrams. The good news?…

Research findings strongly link sleep issues and dementia. In one study of nearly 8,000 adults, people ages 50 to 70 who regularly slept less than six hours per night had a 30 percent higher risk of developing dementia than those who slept the seven hours or more recommended by the Centers for Disease Control and Prevention (CDC).[3]That said, researchers don’t yet know if poor sleep directly causes dementia, says Michelle Jonelis, MD, a board-certified sleep medicine physician at Lifestyle Sleep in Mill Valley, California. In some cases, sleep problems may be an early sign of dementia onset.[4] But scientists have discovered…

Decadal plan for semiconductors. Semiconductor Research Corporation https://www.src.org/about/decadal-plan/ (2021).Generative AI spurs new demand for enterprise SSDs. McKinsey & Company https://www.mckinsey.com/industries/semiconductors/our-insights/generative-ai-spurs-new-demand-for-enterprise-ssds (2024).Yoon, C.-W. The fundamentals of NAND flash memory: technology for tomorrow’s fourth industrial revolution. IEEE Solid State Circuits Mag. 14, 56–65 (2022).Article  Google Scholar  Mohan, V. et al. Modeling power consumption of NAND flash memories using FlashPower. IEEE Trans. Comput. Aided Des. Integr. Circuits Syst. 32, 1031–1044 (2013).Article  ADS  Google Scholar  LeCun, Y., Bengio, Y. & Hinton, G. Deep learning. Nature 521, 436–444 (2015).Article  ADS  CAS  PubMed  Google Scholar  Kim, K. & Park, M. Present and future, challenges of high…