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RESEARCH BRIEFINGS 26 November 2025 Soil produced by the gradual breakdown of rock forms the planet’s thin but crucial ‘skin’. Analyses of a tectonically active landscape along the San Andreas fault aim to address a long-standing question in geomorphology and landscape evolution: what sets the pace at which rock transforms to soil?
MindImmune targets clinical trials of drug that blocks the harmful recruitment of peripheral immune cells into the brain. US biotech MindImmune Therapeutics has secured a $10.2 million extension to its Series A financing, bringing the total round to $30 million as targets first-in-human trials of its immune-system focused approach to neurodegeneration. The proceeds will be used primarily to move the Cambridge, MA-based company’s lead drug candidate into Phase 1 clinical trials in Alzheimer’s disease. For years, drug developers have focused on the role of amyloid and tau proteins in neurodegenerative disease, but MindImmune is looking elsewhere for answers. The company…
Precipitation-based purification could help make therapeutic mAbs more accessible, according to the Gates Foundation, which has awarded $3.1 million to a team using the approach as part of an effort to cut the cost of such drugs to $10 per gram. The grant will support scientists at Rensselaer Polytechnic Institute (RPI) in New York who are working on a low-cost alternative to the affinity-based purification methods used in the production of monoclonal antibodies (mAbs). Affinity-based purification accounts for a significant proportion of costs, according to Todd Przybycien, PhD, professor, project leader, and head of RPI’s chemical and biological engineering department.…
Most holiday leftovers last 2–4 days, so eat or freeze everything by Monday.Refrigerate leftovers within 2 hours and keep your fridge below 40°F for safety.Many dishes freeze well for up to 4 months—just label, date and reheat thoroughly. For many Americans, a few days of turkey sandwiches, mashed potatoes and pumpkin pie after Thanksgiving is an annual tradition. Using up every bit of those leftovers isn’t just delicious—it’s also a great way to stretch your grocery budget and reduce food waste. But how long can you safely keep holiday leftovers in the fridge? And what’s the best way to extend…
Every Sunday, I sit down with my planner and map out my entire week—meals, meetings, workouts…all of it. I love a plan. And typically, that plan includes three to four gym sessions, plus a couple active recovery days and, of course, a standing pickleball game.
“As a nurse and a woman who has struggled with weight loss and a slow metabolism her whole adult life, trying Lumen was eye-opening and validating. Combining modern technology with time-tested nutrition science, it provides a unique approach to understanding and managing your bodily functions. Of course, as with any lifestyle change, making a habit in a short amount of time can be tricky.”
Nature, Published online: 26 November 2025; doi:10.1038/d41586-025-03451-4Fossils newly discovered in Ethiopia indicate that previously unidentified foot bones belong to the ancient human relative Australopithecus deyiremeda.
Credit: Tonpor Kasa/Getty Images Scientists at the University of Geneva (UNIGE) and the Geneva University Hospital (HUG) have engineered a new CAR T cell therapy approach that can destroy glioblastoma cells. The new lab-engineered therapy, details of which are published in the Journal for ImmunoTherapy for Cancer, targets Tenascin-C (TNC), a protein secreted in the extracellular matrix by glioblastoma cells that is found within the glioblastoma tumor microenvironment. In preclinical trials, these CAR T cells induced tumor regression showing their potential as a new method to address this hard-to-treat brain cancer. “Glioblastoma presents as a mass in the brain, consisting…
Potential Risks of the No-Bread, No-Dairy, No-Meat, and No-Sugar DietDairy, bread, meat, and sugar are key parts of many people’s diets. If you don’t replace them carefully, you may face health challenges, including unhealthy or unsustainable weight loss and nutrient deficiencies.Here are some reasons it might be risky to eliminate these food groups.BreadWhile white bread may increase your risk of weight gain, whole-grain bread may help you manage your weight, research suggests.[1]Whole grains provide fiber, minerals, and vitamins that are essential for your health. Refined flours — used in white breads, pizza bases, and so on — are nutrient-poor in…
Need a meal that is easy and delicious to end your day? Look no further! These cozy and comforting dinners come together in just one pot or skillet, making them easy and simple to prepare. Plus, these dishes contain at least 20% of two or more of vital nutrients like vitamin A, vitamin C, vitamin E and zinc, which can help support your immune system. Try options like our White Bean Skillet and our High-Protein Balsamic Chicken Orzo for a hearty meal that will keep you feeling your best. White Bean Skillet Photographer: Jen Causey, Food Stylist: Jennifer Wendorf, Prop…