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Bracco Imaging and Limula, a life science tools company specializing in automated cell and gene therapy manufacturing solutions, launched a R&D project in collaboration with Nicola Vannini, PhD, who specializes in T-cell metabolism at the University of Fribourg, Switzerland. “We see tremendous potential in innovative approaches to some of the key cell manipulation steps required to deliver improved patient outcomes,” noted Vannini. “My team is looking forward to evaluating the impact of these new technologies on the fitness of the cell products.” The complex manufacturing of cell and gene therapies remains a bottleneck to their widespread adoption in the clinic.…
Credit: ChrisChrisW/Getty Images A study looking at the potential impact of common industrial and agricultural chemicals on the human gut microbiome showed around one in six chemicals slowed the growth of at least one microbe found in the gut. Previous research shows this kind of effect on the gut microbiome could reduce the amount of beneficial bacteria in the gut that help us to digest our food and maintain good overall health and promote the growth of strains resistant to the chemicals and to antibiotics. As reported in Nature Microbiology, the researchers tested 1076 chemicals that could enter human bodies…
Abbott recalled three million glucose sensors over inaccurate low readings.FreeStyle Libre 3 and 3 Plus sensors caused 736 severe events, including seven deaths worldwide.Users should check their sensor’s serial number and request a free replacement if affected. Abbott just announced a “medical device correction” for approximately three million glucose sensor monitors in the U.S., according to a company announcement. This is due to the affected sensors providing inaccurate low glucose readings, which can lead to life-threatening complications. The affected Abbott sensors are the FreeStyle Libre 3 and FreeStyle Libre 3 Plus sensors distributed to those with type 1, type 2…
Researchers found that fighters with cognitive impairments had a higher glymphatic index, which deteriorated significantly with more knockouts.Image credit:©iStock.com, EyeEm Mobile GmbHUnder the glow of the arena lights, the two combatants square off. For professional fighters, such as boxers and mixed martial artists, traumatic brain injuries are an occupational hazard. But repeated head trauma, even ones that don’t result in a knockout, can pack a punch against the brain and are a risk factor for neuro-degenerative and psychiatric conditions.In the brain, the glymphatic system acts like the brain’s plumbing and garbage disposal, clearing out waste products. However, worsened function of…
In a deadlift, for example, the foot becomes an anchor. When you press through the middle of your foot and allow the toes to spread, the entire chain of muscles, from the arches to the glutes, activates more efficiently. As those muscles begin to engage, you’ll even start to feel fatigue in your feet, a sign that your foundation is finally being challenged and strengthened.
The study reported that taking 100mg of Tongkat Ali daily for 12 weeks has significantly reduced symptoms of menopause — especially in areas related to physical and sexual health — based on the Menopause-Specific Quality of Life (MENQOL) questionnaire. Tongkat Ali is usually studied for its aphrodisiac effects in men. The current study is said to be the first-of-its-kind that assesses its effects in alleviating menopausal symptoms, the study researchers from Universiti Kebangsaan Malaysia and Biotropics Malaysia wrote in the World Journal of Clinical Cases. A total of 138 women aged 40 to 55, mostly from the Malay ethnicity, were…
NXT USA has received independent third-party testing to back the claims of its patented blend of tender okra pods (Abelmoschus esculentus) and winter cherry (Withania somnifera), Digexin, in supporting digestive health. This enables brands to use “compliant, ready-to-use claim language” for finished products in accordance with the supplement’s recommended use in the US. Digexin is “neither a probiotic nor a laxative,” but claims to ease physical discomfort related to an upset stomach within seven days. It simultaneously relieves various symptoms often associated with occasional constipation, including occasional gastrointestinal discomfort, gas, and bloating.Human research conducted on Digexin produced clinical evidence supporting…
People with high cholesterol who eat more antioxidants may have a lower risk of death.Vitamin E showed the strongest protective effect among all the antioxidants studied.The study suggests that lowering chronic inflammation is important for overall health. If you’re one of the tens of millions of Americans who have elevated or borderline-elevated cholesterol, you’ve probably heard about it from your doctor. And for good reason: Cholesterol is a really important health metric to watch because it’s a major risk factor for cardiovascular disease, type 2 diabetes and stroke. While medications can help control cholesterol levels, the foods you eat are…
Conferences offer researchers from under-represented backgrounds a chance to network.Credit: Dave Kotinsky/GettySeveral US conferences that bring together scientists from under-represented groups have seen their attendance levels drop this year, in the wake of funding cuts and directives from the administration of US President Donald Trump targeting diversity, equity and inclusion (DEI) initiatives.Such conferences typically provide crucial networking opportunities for scientists from marginalized backgrounds, including Black, Latino and Indigenous researchers. Fewer people attending this year means fewer chances for students and scientists to advance their careers, says Allen Pierre-Louis, a physicist and PhD student at Duke University in Durham, North Carolina.…
Credit: STEVE GSCHMEISSNER/Getty Images University of Cambridge researchers have developed a machine learning algorithm that facilitates accurate spatial quantification of tumor tissue on digital pathology images, potentially enabling personalized treatment decisions guided by both what the tumor looks like and what its biology reveals. The tool, named SMMILe (Superpatch-based Measurable Multiple Instance Learning), not only matches or exceeds the performance of current state-of-the-art whole-slide image (WSI) tissue classification tools for the detection of cancer cells in tumor biopsies and surgical sections, but also predicts where the tumor lesions are located and the proportion of regions with different levels of aggressiveness.…