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In a market where consumers increasingly expect supplements to deliver measurable benefits, transparent and responsible marketing is essential. At their core, dietary supplements claims are regulated health-related claims, and they must be properly substantiated.Here, Phyllis Marcus, vice president of BBB National Programs’ National Advertising Division, discusses the key dietary supplement case decisions of 2025 and what marketers should take away from them. NI: What stood out in NAD’s supplement case decisions this year? Phyllis Marcus: In 2025, we reviewed a wide variety of supplement claims. For example, in the recent CataKor NAD+ case, NAD evaluated claims that the product could…

A 1985 squash casserole recipe turned out to be a hit at a holiday dinner.The dish is simple, creamy, and uses pantry-friendly ingredients like soup and stuffing mix.It’s flexible too—try frozen squash or mix in bacon for added flavor and protein. Two of my great loves are shopping at thrift stores and trying out vintage recipes, so any time I get to combine the two hobbies it’s a win in my book. Recently, I came upon the motherlode: a pile of vintage cookbooks on sale for 49 cents each at a local thrift store. Needless to say, I bought them…

Some Lactobacillus species are thought to be beneficial to the eye.Credit: SCIMAT/Science Photo LibraryScience is full of happy little accidents, as Anthony St Leger and his research team have learnt. They were trying to study the microorganisms that live on the surfaces of the eyes of mice, but were having trouble getting the bacteria to grow in the laboratory. Then, there was a moment of serendipity. “We were culturing bacteria and we forgot a plate in a chamber,” explains St Leger, an ocular immunologist at the University of Pittsburgh in Pennsylvania.Nature Outlook: The human microbiomeWhen the team discovered the plate…

Doctor-founded women’s health supplement brand Perelel has netted a US$27 million investment to boost its clinically proven products designed to support women throughout their entire hormonal lifecycle. The recent investment round includes Prelude Growth Partners alongside existing investors Unilever Ventures, Willow Growth Partners, and Selva Ventures.“This moment validates what we’ve built over the past five years: a business that proves women trust and return to brands that invest in clinical rigor and medically backed solutions,” says Victoria Thain Gioia, Perelel co-founder and CEO.Gioia, alongside her co-founders Alex Taylor and Dr. Banafsheh Bayati, leveraged this proactive funding to replace early angel…

“I just can’t make it tonight. You have fun without me.” Across much of the animal kingdom, when infection strikes, social contact shuts down. A study headed by researchers at The Picower Institute for Learning and Memory of MIT has now detailed how the immune and central nervous systems implement this sickness behavior. The scientists and their collaborators used multiple methods to demonstrate causally that interleukin-1 beta (IL-1β) directly modulates activity of IL-1 receptor 1 (IL-1R1)-expressing neurons in the brain’s dorsal raphe nucleus (DRN), activating connections with the intermediate lateral septum to shut down social behavior. “Our findings show that…

Long shot Phase 3 trial finds semaglutide did not deliver a statistically significant reduction in Alzheimer’s progression. Pharma giant Novo Nordisk’s effort to repurpose semaglutide (better known as diabetes and weight loss drugs Ozempic and Wegovy) for early-stage Alzheimer’s has concluded with two large Phase 3 studies failing to show a measurable effect on disease progression. Despite clearly being a long shot for the company, the results are a setback for one of the most closely watched programs exploring GLP-1–based therapies beyond metabolic disease. Ever since we first suggested back in 2023 that GLP-1 therapies may turn out to be…

The Mediterranean diet delivers key health benefits that support your heart, brain and weight management.The dish includes roasted salmon and salsa made of corn, red bell pepper and scallions cilantro.These Roasted Salmon Tacos provide protein, omega-3 fatty acids, fiber and phytonutrients. When I think about making dinner, I usually start by asking myself three questions. “What do I want to eat?” “What does my family want to eat?” And the last question: “How much time do I have?” Because I have a solid foundation in nutrition (I’m a registered dietitian) and cooking (I’m a trained chef and recipe developer), I…

Timothy Hearn, principal investigatorDepartment of Genomic Medicine, University of Cambridge, Cambridge, UKtjh70{at}cam.ac.ukWe welcome Sheldon and Wright’s emphasis on social determinants of health rather than screening,1 but universal newborn whole genome sequencing (WGS) should be seen as an evolution of the heel prick programme, rather than a costly detour into genomics for its own sake. Biochemical screening already tests nine conditions; adding WGS widens that net to >200 treatable disorders and creates a …

COP30 left many countries disappointed because no new road maps were created to help nations transition away from fossil fuels.Credit: Wagner Meier/GettyTen years after the Paris agreement was adopted, world leaders left the United Nations COP30 climate summit in Belém, Brazil, with an outcome that kept the process alive but does little to stave off the perils of global warming. Many scientists walked away dismayed and disappointed.Despite years of commitments and research that have laid the groundwork for action, the climate summit of achieved “essentially nothing”, says Johan Rockström, director of the Potsdam Institute for Climate Impact Research in Germany.But,…

Chinese senior woman looking outside. Exposure to famine in utero can have a lifelong impact on the risk of catching infectious diseases, according to a study investigating the repercussions of a major food crisis in mid-twentieth century China. The research into the Great Chinese Famine, which lasted from around 1958 to 1962, also showed that this vulnerability passed down through generations. The findings demonstrate the lifelong effects of prenatal famine exposure on the body and suggest adequate prenatal nutrition could reduce the burden of infectious diseases through generations. “Our study highlights the long-term and intergenerational impacts of large-scale societal shocks…