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Researchers led by a team at INSERM and King’s College London have shown how stretching the skin stimulates immune cells and increases the skin’s ability to absorb large molecules, including those present in vaccines. Using a device that applies suction pressure to stretch the skin, the researchers reported that skin stretching activated a local immune response and increased skin permeability without tissue damage via the opening of hair follicles. They also reported that applying vaccines topically while stretching the skin resulted in more effective immunization than subcutaneously injecting the vaccine in mice. “Just stretching the skin was more effective than…

Julie Gould 00:01Hello and welcome to Working scientist, a Nature Careers podcast. I’m Julie Gould.This is the second episode of our career planning series. Each episode concludes with the sponsored slot from the International Science Council, with support of the China Association for Science and Technology.The ISC is exploring how early and mid-career researchers can navigate their careers in a constantly evolving scientific landscape through conversations with emerging and established scientists.In the first episode of this series, we heard from career coaches and guidance practitioners what career planning is.It is taking a strategic view of your career experiences, learning from…

The new report from the Federal Institute for Risk Assessment (BfR) suggests the new 20 µg/day limit—a big drop from EFSA’s Tolerable Upper Intake Level of 100 µg/day (4,000 IU)—as a result of health concerns related to intermittent ‘bolus’ dosing. The German body is said to be “pushing for the same approach across Europe” as the European Commission has not yet set harmonized legal maximum levels for vitamin D in supplements.Daily supplementation is the standard recommendation across most European guidelines, but there are some products available providing ‘bolus doses’ of up to 50,000 IU, marketed to be taken once a…

Taiwanese probiotic and postbiotic developer Glac Biotech has secured regulatory approval in the US for its core probiotic strain CP-9 (Bifidobacterium lactis CCTCC M 2014588), scientifically backed for its role in gut health and immune regulation. The US FDA deems the ingredient Generally Recognized as Safe (GRAS). Glac Biotech is the only probiotic raw material manufacturer in Taiwan to hold multiple FDA GRAS approvals, following the recognition of its Lactobacillus rhamnosus MP108 in 2023.According to the FDA filing, CP-9 is authorized for use at levels up to 1 billion colony-forming units (CFUs) per serving in a wide range of food…

Credit: the rads/Getty Images Lung cancer remains the leading cause of cancer-related deaths worldwide, claiming more lives each year than breast, prostate, and colon cancers combined. Screening high-risk individuals with low-dose CT scans has been shown to reduce mortality, but the approach comes with a drawback: high false-positive rates. Many benign pulmonary nodules—small round or oval growths in the lungs—are mistakenly flagged as suspicious, leading to unnecessary procedures, heightened patient anxiety, and increased healthcare costs.A new study in Radiology reports that an artificial intelligence (AI) deep learning tool could help solve this problem. By analyzing CT scans, the algorithm more…

Few people are on their feet more than nurses. With shifts that span the entire day, these essential workers are constantly on the go, helping patients for hours at a time.  Standing for hours on end, these nurses need shoes with ample cushion and support. Healthcare providers also frequently have to replace their sneakers, since they’re put through the paces day in and day out. Nurses seeking a balance between comfort and cost are purchasing these Zove running shoes. They’re only $24 but compare to expensive brands’ $150 shoes, according to reviewers. In fact, one user said they “bought two…

The rate of Alzheimer’s diagnosis has declined steadily in recent decades, but as baby boomers age, the number of new cases continues to rise. The top risk factor for dementia is age, and by 2030 more than one in five Americans will be 65 or older. That means the prevalence of Alzheimer’s in the U.S. could exceed 13.8 million people by 2060.If current trends continue, many of them will have no place to go. Save Our Seniors, a collaboration of the American Health Care Association and the National Center for Assisted Living, estimates that more than 770 nursing homes have…

Nature, Published online: 17 September 2025; doi:10.1038/d41586-025-02704-6Soft devices made by rolling up rubber-like sheets patterned with 2D electronics can monitor, stimulate and navigate deep tissue in animal models.

A research effort led by scientists from the Keck School of Medicine at the University of Southern California (USC) has led to the development of more mature and complex lab-grown kidney progenitor organoids. Building on previous work where they constructed organoids composed of nephrons as well as organoids resembling collecting ducts, the team now reports that they have combined both types of organoids to form new mouse and human structures dubbed “assembloids.”  Full details of the work are published in a new Cell Stem Cell paper titled “Spatially patterned kidney assembloids recapitulate progenitor self-assembly and enable high-fidelity in vivo disease…

This postdoc is turning fields into data-rich digital twins to track crop growth and find sustainable management practices for farmers.Image credit:Prateek Singh, ©iStock, JJ GouinQ | Write a brief introduction to yourself including the lab you work in and your research background. My name is Mukta Sharma. I am a research associate in the Basso Digital Agronomy lab at Michigan State University. We focus on finding sustainable management practices for farmers of US Midwest for major crops like corn, wheat, and soybeans using SALUS crop simulation models, remote sensing, and field collected data.Q | How did you first get interested…