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Credit: JUAN GAERTNER/ Science Photo Library / Getty Images Researchers at the University of Cambridge, U.K., have developed a two-part “prodrug” system that can activate the immune system through the Stimulator of Interferon Genes (STING) pathway, allowing it to fight cancer without causing harm to healthy tissues. Published in the journal Nature Chemistry with the title “Tumor-specific STING agonist synthesis via a two-component prodrug system,” the research focuses on a specific pathway in our cells, called the STING pathway, that acts as an internal alarm system. It activates the human innate immune system when the body is attacked by pathogens,…
The probiotic strain, marketed as Gyntima Balance outside the United States, improved the microbial balance, shifting from troublesome Community State Types associated with dysbiosis toward Lactobacillus-dominated vaginotypes.“This is a crucial distinction: The product doesn’t just alter the composition slightly, it promotes a complete change in the type of vaginal microbiota to one that is clinically recognized as healthy,” Dr. Marta Pérez, lead researcher and R&D manager at AB-Biotics, told NutraIngredients.“This result provides robust clinical evidence for the efficacy of a specifically selected oral probiotic for vaginal health. It validates the oral-gut-vagina axis by confirming that the probiotic can survive gastrointestinal…
Reusable water bottles, especially plastic bottles or those with small parts, can breed bacteria. Bacteria may adhere better to plastic materials and multiply faster in certain environments.An expert recommends rinsing water bottles daily and doing a deeper clean every two to three days. If a reusable water bottle is your go-to for staying hydrated, you’re probably refilling it several times per day—at the gym, while running errands or between work calls. But how often do you actually stop to clean it? We asked a microbiologist and food safety expert about the ins and outs of washing your water bottle—you may need…
Mechanical strain, such as that experienced while rubbing cream onto skin, makes skin more permeable, alters immune pathways, and opens possibilities for non-invasive drug delivery.Image credit:©iStock, RidofranzAs the outermost layer of the body, the skin is under a constant barrage of stimuli, ranging from the benign application of sunscreen to harmful puncture wounds. Sustained mechanical stress due to injury or inflammation triggers the immune defense of the skin.1 In the case of skin stretching, cell adhesion molecules in the epidermis sense this stimulus, leading to cell proliferation, secretion of growth factors, and production of inflammatory modulators.2 For instance, continuous skin…
Sues, H.-D. Functional morphology of the dome in pachycephalosaurid dinosaurs. N. Jb. Geol. Palaontol. Mh. 8, 459–472 (1978). Google Scholar Snively, E. & Theodor, J. M. Common functional correlates of head-strike behavior in the pachycephalosaur Stegoceras validum (Ornithischia, Dinosauria) and combative artiodactyls. PLoS ONE 6, e21422 (2011).Article ADS CAS PubMed PubMed Central Google Scholar Peterson, J. E., Dischler, C. & Longrich, N. R. Distributions of cranial pathologies provide evidence for head-butting in dome-headed dinosaurs (Pachycephalosauridae). PLoS ONE 8, e68620 (2013).Article ADS CAS PubMed PubMed Central Google Scholar Evans, D. C., Schott, R. K., Larson, D. W., Brown, C. M. &…
Functional probiotic pioneer, BioGrowing is spotlighting targeted biotic innovations like its Flora-Focus strains to aid in Helicobacter pylori infections and support the vaginal microbiome, immune health, and weight management.Nutrition Insight sits down with Yuan Feng, Ph.D., an academic scientist at BioGrowing, to discuss the company’s current offerings, future R&D, and how its offerings speak to emerging global trends and consumer demand for natural health solutions.The company is showcasing its probiotic solutions at Vitafoods Asia 2025 (September 17–19) in Bangkok, Thailand, at Hall 7, stand# R36.Can you tell us about some of BioGrowing’s flagship strains and solutions?Feng: I would like to introduce…
Without calorie restriction, we might add.
Practice meditation, deep breathing, and mindfulness exercises to reduce stress and promote relaxation and proper tone in the vagus nerve, which helps us stay relaxed10. Engage in yoga, tai chi, or qigong to combine physical activity with stress reduction. Along those lines, prioritize getting adequate, quality sleep to allow for rest and restoration of the gut-brain axis.
Alzheimer’s disease has proved to be a tricky target, and researchers and drug developers have been pursuing effective treatments for decades. Debates rage over the disorder’s underlying causes, and various approaches have faced one hurdle after another. But the field has reached a turning point. Over the past four years the U.S. Food and Drug Administration has approved several therapies that address some of the condition’s potential biological roots rather than merely mitigating symptoms—a key scientific milestone. Despite the advances, however, there is still a long list of open questions and so much work to be done.The brains of people…
Former Senior Beauty & Lifestyle EditorJamie Schneider is the former Senior Beauty Editor at mindbodygreen. She has a B.A. in Organizational Studies and English from the University of Michigan, and her work has appeared in Coveteur, The Chill Times, and Wyld Skincare.