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Many of us think of brain health as something we worry about later, when we start forgetting names or misplacing keys. But new research suggests that the earliest signs of Alzheimer’s and Parkinson’s may show up years before any memory lapses do—and in places you might not expect.

Nature, Published online: 03 November 2025; doi:10.1038/d41586-025-03448-zCells change shape to move efficiently in a range of spatial environments. This response can be informed by the cell’s memory of past deformation.

Member’s Mark Super Greens sold at Sam’s Club are being recalled nationwide.The greens powder is connected to a Salmonella outbreak with 11 illnesses, including 3 hospitalizations.Consumers should discard or return product and contact a doctor if experiencing symptoms. The U.S. Food and Drug Administration (FDA) just announced a recall on greens powder sold at Sam’s Club stores nationwide. This is due to its connection in an active Salmonella outbreak. The Member’s Mark Super Greens dietary supplement powder affected includes organic moringa leaf powder that has been found to be the source of the contamination. All Member’s Mark Super Greens are…

Stocking up on seasonal fall foods is an easy, affordable and nutritious way to reduce inflammation.Excellent options include pumpkin, kale, mushrooms, pears, walnuts and cranberries for their anti-inflammatory properties.For the most benefits, eat plenty of colorful foods and choose whole foods most often. Inflammation seems to be the health buzzword of the year, and it’s finally getting the attention it deserves. While some inflammation is normal—like your body responding to a cut or brief illness—chronic, low grade inflammation can quietly take a toll on your body and contribute to a range of health issues. The good news? Your diet can…

uniQure has acknowledged that what it called “game changing” data in September showing significant slowing of Huntington’s disease (HD) progression in patients treated with its gene therapy candidate AMT-130 may not be enough to secure FDA approval. [uniQure] uniQure acknowledged today that what it called “game changing” data in September showing significant slowing of Huntington’s disease (HD) progression in patients treated with its gene therapy candidate AMT-130 may not be enough to secure FDA approval. In a statement uniQure said that based on a recent pre-Biologics License Application (BLA) meeting with agency officials, the company “believes that the FDA currently no longer…

Scorpio is a sign known for being mysterious, seductive, and even a bit taboo—perfect energy for October as we move through spooky season. And from now until November 21, the sun is moving through the sign of Scorpio, bringing with it a few retrogrades, a Taurus full moon, and more.

Michael Marmot, directorUCL Institute of Health Equity, London, UKPandemic preparedness and response must be rooted in trust, cooperation, and commitment to greater health equity, says Michael MarmotThe covid-19 pandemic brought to mind Albert Camus’s The Plague. In 2020, a colleague and I quoted a reading of Camus that “the pestilence is at once blight and revelation. It brings the hidden truth of a corrupt world to the surface.” Less poetically, but more dramatically, the evidence is clear: pandemics reveal and amplify inequalities in society.1To examine the evidence of this inequality-pandemic cycle and to recommend how to build health security in…

Credit: jadamprostore/Getty Images A novel bioinformatics tool built by researchers at the Wellcome Sanger Institute is able to identify a range of structural genetic variants that are responsible for causing rare diseases using primarily standard short-read whole-genome sequencing data. While long read sequencing is still the “gold standard” for identifying and classifying complex structural variants in the genome, the new tool is able to overcome known limitations of short read sequencing by computationally improving filtering, classification and validation steps to pick up structural variants that would otherwise be missed. Many rare diseases are caused by different types of genetic variants,…

Pancreatic tumors can evade immune detection by displaying a sugar molecule, typically found on healthy cells, on their cell surface.Image credit:©iStock, AegeanBlueStories of wolves disguising themselves as Little Red Riding Hood’s grandmother—or predators hiding in sheep’s clothing—are reminders of how deception can mask danger. Cancer, too, can be a master of disguise, slipping past the body’s defenses undetected. Among them, pancreatic cancer is especially notorious for its stealth, often remaining hidden until it’s far too late.This motivated immunologist and glycobiologist Mohamed Abdel-Mohsen from Northwestern University to investigate pancreatic tumors’ evasion tactics, particularly looking at their use of complex sugars, or…

At the US Environmental Protection Agency, scientists say proposed cuts will gut research. Credit: Eric Lee/Bloomberg via GettyFor 30 years, the US Environmental Protection Agency (EPA) has conducted controlled air-pollution studies at a state-of-the-art facility at the University of North Carolina at Chapel Hill. The facility is equipped to test numerous airborne pollutants, including ozone, diesel, wildfire smoke and chlorine. Data collected in its chambers have been pivotal to establishing stricter air-quality standards for deadly pollutants, and have been instrumental in protecting the health of people in the United States.However, in February, shortly after US President Donald Trump took office,…