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Credit: Steve Gschmeissner/Science Photo Library Cancer immunotherapies, such as immune checkpoint inhibitors (ICIs), are effective against many types of cancer. However, these treatments don’t work well for some tumors, including ovarian cancer (OC). MIT researchers have now designed polymer-coated nanoparticles (NPs) that can deliver the immune-stimulating molecule IL-12 directly to ovarian tumors. Preclinical studies showed that when given alongside immune checkpoint inhibitor therapy, IL-12 helped the immune system launch an attack on cancer cells. Working with a mouse model of ovarian cancer, the researchers demonstrated that the combination treatment could eliminate metastatic tumors in more than 80% of animals. When…

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Evident announced its sixth annual Image of the Year competition is now open for entries through January 30, 2026. The contest recognizes the best in scientific imaging worldwide—it’s a celebration of art, science, and technical mastery. Building momentum every year, previous winners have been featured in major global news outlets and respected scientific trade publications. Evident invites participants to join them in illuminating the unseen by sharing the remarkable discoveries they’ve made under the microscope. Contestants may enter by uploading up to three images, with a description of the equipment used, at Evidentscientific.com/en/landing/ioty-six-annual. Winners will be selected by a jury…

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Sam’s Club offers a fully cooked Thanksgiving feast for 10 people under $100.The 2025 menu adds new sides like green beans with cranberries and garlic herb corn.Orders open November 1 with pickup, delivery and in-store sampling options available. Planning a delicious Thanksgiving dinner that won’t break the bank? We hear you. That’s why we’re loving meal deals from our favorite grocery stores, from Aldi to Walmart. Most recently putting their hat in the ring is Sam’s Club, who is offering a feast for under $100. The best part about their selection is that it’s a fully pre-cooked dinner that requires…

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Doctors have urged Florida policymakers to reject plans to end childhood vaccine mandates, with others claiming they are being silenced on the matter by their institutions.On 3 September, Florida Surgeon General Joseph Ladapo announced that “the Florida health department is going to be working to end all vaccine mandates in Florida law.” He said, “Who am I, as a government or anyone else, to tell you what you should put in your body?”The announcement builds on the decision by Florida Governor Ron DeSantis during the covid-19 pandemic to reject vaccine and mask mandates for schools and workplaces.Florida is scheduled to…

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Sometimes, the cold, dark days of winter have you craving a cozy blanket and the couch — not the gym. But getting daily movement all year long is important for overall health, especially if you’re prone to the winter blues or low energy during this season.That’s where winter workouts come into play — the types that are ideal for snowy or rainy weather. “Workouts that elevate your heart rate will help you stay warm and work up a nice sweat,” says Jess Evans, a certified USA Boxing coach and trainer with the virtual boxing gym FightCamp.Read on for tips on…

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Stay warm and cozy with these quick vegetarian soup recipes that you can whip up in 30 minutes. These flavorful soups run the gamut from minestrone to creamy vegetable soups. Any of them would make a healthy, comforting dinner with a salad or a piece of crusty bread on the side. Recipes like our Easy Green Tortellini Soup and our Vegetarian Lasagna Soup are so delicious that you’ll want to make them every night of the week. You may even want to cook up a double batch. Love these recipes? Join MyRecipes to save them all with one click. It’s so easy—and…

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Credit: Blablo101 / iStock / Getty Images Plus It’s been less than six months since the news of Baby KJ broke, a watershed moment for precision medicine with the first successful demonstration of a personalized in vivo gene-editing therapeutic. But for Becca Ahrens-Nicklas, MD, PhD, the physician who cared for KJ, and Kiran Musunuru, MD, PhD, the cardiologist and gene-editing researcher who designed the therapy, that single success was the requisite first domino to fall in the journey to developing approved gene-editing therapies for the countless other individuals with monogenic inherited diseases. What unfolded at the Children’s Hospital of Philadelphia…

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