DNA & Genetics CRISPR Screens Pinpoint Genetic Tweaks That Improve CAR T Therapies for Multiple MyelomaBy adminSeptember 25, 20250 Scientists from Mass General Brigham and the Broad Institute of MIT and Harvard have used CRISPR screens to identify genetic…
DNA & Genetics CRISPR Reveals EML4-ALK Variants Drive Distinct Lung Tumor Growth in MiceBy adminSeptember 24, 20250 Not all genetic fusions are created equal. In a new Cancer Discovery study, titled “EML4-ALK variant-specific genetic interactions shape lung…
DNA & Genetics CRISPR Activation Restores SCN2A Loss, Improves Neurodevelopmental Outcomes in MiceBy adminSeptember 19, 20250 Children who are born with a single functioning copy of the SCN2A gene develop a condition called SCN2A haploinsufficiency, one…
DNA & Genetics CRISPR Mouth-Swab Test Could Transform Tuberculosis ScreeningBy adminSeptember 17, 20250 More than 10 million people develop tuberculosis (TB) each year, yet about 40% go undiagnosed. The main culprit is reliance…
