Browsing: Genome

Northwestern researchers unveil the most detailed 3D genome maps, revealing how DNA folding regulates genes and disease risk. For decades,…

Timothy Hearn, principal investigatorDepartment of Genomic Medicine, University of Cambridge, Cambridge, UKtjh70{at}cam.ac.ukWe welcome Sheldon and Wright’s emphasis on social determinants…

General methodsDNA amplification was conducted by PCR using Phusion U Green Multiplex PCR Master Mix (ThermoFisher Scientific) or Q5 Hot…

Credit: vchal/ Getty Images Pregnancy loss may occur in as many as 25 percent of all pregnancies, mostly during the…

Credit: Rost-9D/Getty Images Separate studies led by scientists at Dartmouth Hitchcock Medical Center (DMHC) and Queens University offer some clarity…

3D genome mapping reveals how noncoding DNA elements, such as enhancers, interact with distant genes to regulate expression.Image credit:©iStock, Perkasa RambeDrug…

Before cells can divide by mitosis, they first need to replicate all of their chromosomes, so that each of the…

Credit: Science Photo Library – ROGER HARRIS/Getty Images Offering whole genome sequencing (WGS) to women with breast cancer could open…

For decades, gene-editing science has been limited to making small, precise edits to human DNA, akin to correcting typos in…

Robertsonian chromosomes (ROB) are a type of structurally variant chromosome that is created when two chromosomes fuse together to form…