Browsing: targeting

In Aging, researchers have described how they removed visceral fat from older male mice by targeting the metabolic regulatory protein…

Credit: KATERYNA KON/SCIENCE PHOTO LIBRARY/Getty Images Researchers in Japan at Okayama University and Tohoku University have found a way to…

A 3D virtual model of the PKMYT1–PROTAC–CRBN ternary complex depicting how Insilico Medicine’s bifunctional proteolysis-targeting chimera (PROTAC) D16-M1P2 (shown in…

Prostate cancer (PC)—a major global health challenge— presents a wide spectrum of outcomes, from slow-growing tumors to aggressive metastatic disease.…

Mouse proceduresNPp53 mice were maintained on a mixed C57BL/6-129Sv background and have been previously described7. Tamoxifen induction was performed in…

MindImmune targets clinical trials of drug that blocks the harmful recruitment of peripheral immune cells into the brain. US biotech…

General Control enters Novo Nordisk’s Co-Creation Greenhouse to advance multiplex epigenetic editing for complex chronic disease. General Control, a previously…

AGC Biologics and Repair Bio partner to develop an mRNA therapy that shrinks arterial plaques and reduces heart attack risk.…

“The Hallmarks of Aging provide some guidance on how to design interventions and how to discover novel ingredients to target…

Credit: 7activestudio/ Getty Images Researchers at the University of Texas MD Anderson Cancer Center report that heat shock protein 90…