Browsing: targeting

Credit: Pallava Bagla/Getty Images Researchers from the University of Michigan researchers have identified the metabolite itaconate as a potential therapeutic…

Some types of CD8+ T cells (killer T cells) may play a role in the development of multiple sclerosis (MS). This is according to…

Credit: Lars Neumann / iStock / Getty Images Plus Researchers at the University College London (UCL) have identified a central…

Scribe’s CRISPR-based cholesterol reduction therapy is part of a three-pronged approach to combating cardiovascular disease. Genetic medicine biotech Scribe Therapeutics…

In Aging, researchers have described how they removed visceral fat from older male mice by targeting the metabolic regulatory protein…

Credit: KATERYNA KON/SCIENCE PHOTO LIBRARY/Getty Images Researchers in Japan at Okayama University and Tohoku University have found a way to…

A 3D virtual model of the PKMYT1–PROTAC–CRBN ternary complex depicting how Insilico Medicine’s bifunctional proteolysis-targeting chimera (PROTAC) D16-M1P2 (shown in…

Prostate cancer (PC)—a major global health challenge— presents a wide spectrum of outcomes, from slow-growing tumors to aggressive metastatic disease.…

Mouse proceduresNPp53 mice were maintained on a mixed C57BL/6-129Sv background and have been previously described7. Tamoxifen induction was performed in…

MindImmune targets clinical trials of drug that blocks the harmful recruitment of peripheral immune cells into the brain. US biotech…